Dietary antioxidants significantly attenuate hyperoxia-induced acute inflammatory lung injury by enhancing macrophage function via reducing the accumulation of airway HMGB1 V Patel, K Dial, J Wu, AG Gauthier, W Wu, M Lin, MG Espey, DD Thomas, ... International journal of molecular sciences 21 (3), 977, 2020 | 93 | 2020 |
The role of HMGB1, a nuclear damage-associated molecular pattern molecule, in the pathogenesis of lung diseases M Wang, A Gauthier, LA Daley, K Dial, J Wu, J Woo, M Lin, C Ashby, ... Antioxidants & Redox Signaling 31 (13), 954-993, 2019 | 79 | 2019 |
The α7 nicotinic acetylcholine receptor agonist, GTS-21, attenuates hyperoxia-induced acute inflammatory lung injury by alleviating the accumulation of HMGB1 in the airways and … RA Sitapara, AG Gauthier, SI Valdés-Ferrer, M Lin, V Patel, M Wang, ... Molecular Medicine 26, 1-12, 2020 | 40 | 2020 |
Cell cycle re-entry and arrest in G2/M phase induces senescence and fibrosis in Fuchs Endothelial Corneal Dystrophy TL White, N Deshpande, V Kumar, AG Gauthier, UV Jurkunas Free Radical Biology and Medicine 164, 34-43, 2021 | 27 | 2021 |
From nicotine to the cholinergic anti-inflammatory reflex–Can nicotine alleviate the dysregulated inflammation in COVID-19? AG Gauthier, M Lin, J Wu, TP Kennedy, LA Daley, CR Ashby Jr, ... Journal of Immunotoxicology 18 (1), 23-29, 2021 | 27 | 2021 |
Dual effects of supplemental oxygen on pulmonary infection, inflammatory lung injury, and neuromodulation in aging and COVID-19 M Lin, MT Stewart, S Zefi, KV Mateti, A Gauthier, B Sharma, LR Martinez, ... Free Radical Biology and Medicine 190, 247-263, 2022 | 16 | 2022 |
The nitric oxide donor,(Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl) amino] diazen-1-ium-1, 2-diolate (DETA-NONOate/D-NO), increases survival by attenuating hyperoxia-compromised … A Gore, AG Gauthier, M Lin, V Patel, DD Thomas, CR Ashby Jr, LL Mantell Biochemical pharmacology 176, 113817, 2020 | 15 | 2020 |
Cultivated autologous limbal epithelial cell (CALEC) transplantation: Development of manufacturing process and clinical evaluation of feasibility and safety UV Jurkunas, J Yin, LK Johns, S Li, H Negre, KL Shaw, L Samarakoon, ... Science Advances 9 (33), eadg6470, 2023 | 14 | 2023 |
The positive allosteric modulation of alpha7-nicotinic cholinergic receptors by GAT107 increases bacterial lung clearance in hyperoxic mice by decreasing oxidative stress in … AG Gauthier, J Wu, M Lin, R Sitapara, A Kulkarni, GA Thakur, EE Schmidt, ... Antioxidants 10 (1), 135, 2021 | 11 | 2021 |
The α7 nicotinic acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function RA Sitapara, AG Gauthier, VS Patel, M Lin, M Zur, CR Ashby Jr, ... Molecular Medicine 26, 1, 2020 | 9 | 2020 |
2-O, 3-O desulfated heparin (ODSH) increases bacterial clearance and attenuates lung injury in cystic fibrosis by restoring HMGB1-compromised macrophage function M Wang, AG Gauthier, TP Kennedy, H Wang, UK Velagapudi, TT Talele, ... Molecular Medicine 27, 1-17, 2021 | 6 | 2021 |
GAT107-mediated α7 nicotinic acetylcholine receptor signaling attenuates inflammatory lung injury and mortality in a mouse model of ventilator-associated pneumonia by … AG Gauthier, M Lin, S Zefi, A Kulkarni, GA Thakur, CR Ashby Jr, ... Redox Biology 60, 102614, 2023 | 5 | 2023 |
GTS-21, an α7nAChR agonist, increases pulmonary bacterial clearance in mice by restoring hyperoxia-compromised macrophage function RA Sitapara, AG Gauthier, VS Patel, M Lin, M Zur, CR Ashby, LL Mantell Molecular Medicine 26, 1-13, 2020 | 5 | 2020 |
A Standardized Botanical Composition Mitigated Acute Inflammatory Lung Injury and Reduced Mortality through Extracellular HMGB1 Reduction M Yimam, T Horm, A O’Neal, P Jiao, M Hong, L Brownell, Q Jia, M Lin, ... Molecules 28 (18), 6560, 2023 | 3 | 2023 |
FDA-Approved Excipient N, N-Dimethylacetamide Attenuates Inflammatory Bowel Disease in In Vitro and In Vivo Models JB Koya, T Shen, G Lu, A Gauthier, L Mantell, CR Ashby Jr, SE Reznik Fortune journal of health sciences 5, 499, 2022 | 1 | 2022 |
Correction to: GTS-21, an α7nAChR agonist, increases pulmonary bacterial clearance in mice by restoring hyperoxia-compromised macrophage function RA Sitapara, AG Gauthier, VS Patel, M Lin, M Zur, CR Ashby Jr, ... Molecular Medicine 27, 2021 | 1 | 2021 |
The Positive Allosteric Modulation of alpha7-Nicotinic Cholinergic Receptors by GAT107 Increases Bacterial Lung Clearance in Hyperoxic Mice by Decreasing Oxidative Stress in … AG Gauthier, J Wu, M Lin, R Sitapara, A Kulkarni, GA Thakur, EE Schmidt, ... s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2021 | 1 | 2021 |
Hyperoxia-induced macrophage dysfunction and acute lung injury are attenuated by modulation of α7nAChR via reduced HMGB1 hyperacetylation and release A Gauthier, R Sitapara, GS Thakur, L Mantell Free radical biology and medicine 120, S88, 2018 | 1 | 2018 |
CRA, Mantell LL.(2020) Dietary Antioxidants Significantly Attenuate Hyperoxia-Induced Acute Inflammatory Lung Injury by Enhancing Macrophage Function via Reducing the … V Patel, K Dial, J Wu, AG Gauthier, W Wu, M Lin, MG Espey, ... Int J Mol Sci 21 (3), 0 | 1 | |
Modulation of ATM enhances DNA repair in G2/M phase of cell cycle and averts senescence in Fuchs endothelial corneal dystrophy S Ashraf, N Deshpande, Q Cheung, JB Asabere, RJ Wong, AG Gauthier, ... Communications Biology 7 (1), 1482, 2024 | | 2024 |