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Alex Gauthier
Alex Gauthier
Gradient
在 gradientcorp.com 的电子邮件经过验证
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引用次数
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Dietary antioxidants significantly attenuate hyperoxia-induced acute inflammatory lung injury by enhancing macrophage function via reducing the accumulation of airway HMGB1
V Patel, K Dial, J Wu, AG Gauthier, W Wu, M Lin, MG Espey, DD Thomas, ...
International journal of molecular sciences 21 (3), 977, 2020
932020
The role of HMGB1, a nuclear damage-associated molecular pattern molecule, in the pathogenesis of lung diseases
M Wang, A Gauthier, LA Daley, K Dial, J Wu, J Woo, M Lin, C Ashby, ...
Antioxidants & Redox Signaling 31 (13), 954-993, 2019
792019
The α7 nicotinic acetylcholine receptor agonist, GTS-21, attenuates hyperoxia-induced acute inflammatory lung injury by alleviating the accumulation of HMGB1 in the airways and …
RA Sitapara, AG Gauthier, SI Valdés-Ferrer, M Lin, V Patel, M Wang, ...
Molecular Medicine 26, 1-12, 2020
402020
Cell cycle re-entry and arrest in G2/M phase induces senescence and fibrosis in Fuchs Endothelial Corneal Dystrophy
TL White, N Deshpande, V Kumar, AG Gauthier, UV Jurkunas
Free Radical Biology and Medicine 164, 34-43, 2021
272021
From nicotine to the cholinergic anti-inflammatory reflex–Can nicotine alleviate the dysregulated inflammation in COVID-19?
AG Gauthier, M Lin, J Wu, TP Kennedy, LA Daley, CR Ashby Jr, ...
Journal of Immunotoxicology 18 (1), 23-29, 2021
272021
Dual effects of supplemental oxygen on pulmonary infection, inflammatory lung injury, and neuromodulation in aging and COVID-19
M Lin, MT Stewart, S Zefi, KV Mateti, A Gauthier, B Sharma, LR Martinez, ...
Free Radical Biology and Medicine 190, 247-263, 2022
162022
The nitric oxide donor,(Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl) amino] diazen-1-ium-1, 2-diolate (DETA-NONOate/D-NO), increases survival by attenuating hyperoxia-compromised …
A Gore, AG Gauthier, M Lin, V Patel, DD Thomas, CR Ashby Jr, LL Mantell
Biochemical pharmacology 176, 113817, 2020
152020
Cultivated autologous limbal epithelial cell (CALEC) transplantation: Development of manufacturing process and clinical evaluation of feasibility and safety
UV Jurkunas, J Yin, LK Johns, S Li, H Negre, KL Shaw, L Samarakoon, ...
Science Advances 9 (33), eadg6470, 2023
142023
The positive allosteric modulation of alpha7-nicotinic cholinergic receptors by GAT107 increases bacterial lung clearance in hyperoxic mice by decreasing oxidative stress in …
AG Gauthier, J Wu, M Lin, R Sitapara, A Kulkarni, GA Thakur, EE Schmidt, ...
Antioxidants 10 (1), 135, 2021
112021
The α7 nicotinic acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function
RA Sitapara, AG Gauthier, VS Patel, M Lin, M Zur, CR Ashby Jr, ...
Molecular Medicine 26, 1, 2020
92020
2-O, 3-O desulfated heparin (ODSH) increases bacterial clearance and attenuates lung injury in cystic fibrosis by restoring HMGB1-compromised macrophage function
M Wang, AG Gauthier, TP Kennedy, H Wang, UK Velagapudi, TT Talele, ...
Molecular Medicine 27, 1-17, 2021
62021
GAT107-mediated α7 nicotinic acetylcholine receptor signaling attenuates inflammatory lung injury and mortality in a mouse model of ventilator-associated pneumonia by …
AG Gauthier, M Lin, S Zefi, A Kulkarni, GA Thakur, CR Ashby Jr, ...
Redox Biology 60, 102614, 2023
52023
GTS-21, an α7nAChR agonist, increases pulmonary bacterial clearance in mice by restoring hyperoxia-compromised macrophage function
RA Sitapara, AG Gauthier, VS Patel, M Lin, M Zur, CR Ashby, LL Mantell
Molecular Medicine 26, 1-13, 2020
52020
A Standardized Botanical Composition Mitigated Acute Inflammatory Lung Injury and Reduced Mortality through Extracellular HMGB1 Reduction
M Yimam, T Horm, A O’Neal, P Jiao, M Hong, L Brownell, Q Jia, M Lin, ...
Molecules 28 (18), 6560, 2023
32023
FDA-Approved Excipient N, N-Dimethylacetamide Attenuates Inflammatory Bowel Disease in In Vitro and In Vivo Models
JB Koya, T Shen, G Lu, A Gauthier, L Mantell, CR Ashby Jr, SE Reznik
Fortune journal of health sciences 5, 499, 2022
12022
Correction to: GTS-21, an α7nAChR agonist, increases pulmonary bacterial clearance in mice by restoring hyperoxia-compromised macrophage function
RA Sitapara, AG Gauthier, VS Patel, M Lin, M Zur, CR Ashby Jr, ...
Molecular Medicine 27, 2021
12021
The Positive Allosteric Modulation of alpha7-Nicotinic Cholinergic Receptors by GAT107 Increases Bacterial Lung Clearance in Hyperoxic Mice by Decreasing Oxidative Stress in …
AG Gauthier, J Wu, M Lin, R Sitapara, A Kulkarni, GA Thakur, EE Schmidt, ...
s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2021
12021
Hyperoxia-induced macrophage dysfunction and acute lung injury are attenuated by modulation of α7nAChR via reduced HMGB1 hyperacetylation and release
A Gauthier, R Sitapara, GS Thakur, L Mantell
Free radical biology and medicine 120, S88, 2018
12018
CRA, Mantell LL.(2020) Dietary Antioxidants Significantly Attenuate Hyperoxia-Induced Acute Inflammatory Lung Injury by Enhancing Macrophage Function via Reducing the …
V Patel, K Dial, J Wu, AG Gauthier, W Wu, M Lin, MG Espey, ...
Int J Mol Sci 21 (3), 0
1
Modulation of ATM enhances DNA repair in G2/M phase of cell cycle and averts senescence in Fuchs endothelial corneal dystrophy
S Ashraf, N Deshpande, Q Cheung, JB Asabere, RJ Wong, AG Gauthier, ...
Communications Biology 7 (1), 1482, 2024
2024
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