An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules A Basu, NE Bodycombe, JH Cheah, EV Price, K Liu, GI Schaefer, ... Cell 154 (5), 1151-1161, 2013 | 782 | 2013 |
Stromal microenvironment shapes the intratumoral architecture of pancreatic cancer M Ligorio, S Sil, J Malagon-Lopez, LT Nieman, S Misale, M Di Pilato, ... Cell 178 (1), 160-175. e27, 2019 | 465 | 2019 |
HER2 expression identifies dynamic functional states within circulating breast cancer cells NV Jordan, A Bardia, BS Wittner, C Benes, M Ligorio, Y Zheng, M Yu, ... Nature 537 (7618), 102-106, 2016 | 408 | 2016 |
Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis RY Ebright, S Lee, BS Wittner, KL Niederhoffer, BT Nicholson, A Bardia, ... Science 367 (6485), 1468-1473, 2020 | 285 | 2020 |
New target for inhibition of bacterial RNA polymerase:‘switch region’ A Srivastava, M Talaue, S Liu, D Degen, RY Ebright, E Sineva, ... Current opinion in microbiology 14 (5), 532-543, 2011 | 199 | 2011 |
Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma JT Powers, KM Tsanov, DS Pearson, F Roels, CS Spina, R Ebright, ... Nature 535 (7611), 246-251, 2016 | 195 | 2016 |
Structural basis of transcription inhibition by fidaxomicin (lipiarmycin A3) W Lin, K Das, D Degen, A Mazumder, D Duchi, D Wang, YW Ebright, ... Molecular cell 70 (1), 60-71. e15, 2018 | 99 | 2018 |
Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma S Manier, D Huynh, YJ Shen, J Zhou, T Yusufzai, KZ Salem, RY Ebright, ... Science translational medicine 9 (389), eaal2668, 2017 | 78 | 2017 |
HIF1A signaling selectively supports proliferation of breast cancer in the brain RY Ebright, MA Zachariah, DS Micalizzi, BS Wittner, KL Niederhoffer, ... Nature Communications 11 (1), 6311, 2020 | 74 | 2020 |
Reverse Transcriptase Inhibition Disrupts Repeat Element Life Cycle in Colorectal Cancer. M Rajurkar, AR Parikh, A Solovyov, E You, AS Kulkarni, C Chu, KH Xu, ... Cancer Discovery, 2022 | 37 | 2022 |
NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer H Guo, G Golczer, BS Wittner, A Langenbucher, M Zachariah, TD Dubash, ... Molecular Cell 81 (19), 4041-4058. e15, 2021 | 34 | 2021 |
Translational Regulation of Cancer Metastasis DS Micalizzi, RY Ebright, DA Haber, S Maheswaran Cancer Research 81 (3), 517-524, 2021 | 33 | 2021 |
Downregulation of KEAP1 in melanoma promotes resistance to immune checkpoint blockade DB Fox, RY Ebright, X Hong, HC Russell, H Guo, TJ LaSalle, BS Wittner, ... NPJ Precision Oncology 7 (1), 25, 2023 | 7 | 2023 |
Abstract A066: 5z-7-oxozeaenol as an epithelial mesenchymal transition plasticity inhibitor in PDAC E You, IPE Phillips, RY Ebright, N Desai, MJ Raabe, ER Lang, LT Nieman, ... Cancer Research 82 (22_Supplement), A066-A066, 2022 | | 2022 |