| Sustained translational repression by eIF2α-P mediates prion neurodegeneration JA Moreno, H Radford, D Peretti, JR Steinert, N Verity, MG Martin, ... Nature 485 (7399), 507-511, 2012 | 701 | 2012 |
| Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice JA Moreno, M Halliday, C Molloy, H Radford, N Verity, JM Axten, CA Ortori, ... Science translational medicine 5 (206), 206ra138-206ra138, 2013 | 647 | 2013 |
| Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity M Halliday, H Radford, Y Sekine, J Moreno, N Verity, J Le Quesne, ... Cell death & disease 6 (3), e1672-e1672, 2015 | 351 | 2015 |
| Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice M Halliday, H Radford, KAM Zents, C Molloy, JA Moreno, NC Verity, ... Brain 140 (6), 1768-1783, 2017 | 296 | 2017 |
| PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia H Radford, JA Moreno, N Verity, M Halliday, GR Mallucci Acta neuropathologica 130, 633-642, 2015 | 280 | 2015 |
| Targeting the unfolded protein response in neurodegeneration: a new approach to therapy M Halliday, GR Mallucci Neuropharmacology 76, 169-174, 2014 | 131 | 2014 |
| Neuronal mitochondrial dysfunction activates the integrated stress response to induce fibroblast growth factor 21 LM Restelli, B Oettinghaus, M Halliday, C Agca, M Licci, L Sironi, ... Cell reports 24 (6), 1407-1414, 2018 | 90 | 2018 |
| Modulating the unfolded protein response to prevent neurodegeneration and enhance memory M Halliday, GR Mallucci Neuropathology and Applied Neurobiology 41 (4), 414-427, 2015 | 84 | 2015 |
| Fine‐tuning PERK signaling for neuroprotection M Halliday, D Hughes, GR Mallucci Journal of neurochemistry 142 (6), 812-826, 2017 | 69 | 2017 |
| Prions: generation and spread versus neurotoxicity M Halliday, H Radford, GR Mallucci Journal of Biological Chemistry 289 (29), 19862-19868, 2014 | 66 | 2014 |
| What Is Our Current Understanding of PrPSc-Associated Neurotoxicity and Its Molecular Underpinnings? D Hughes, M Halliday Pathogens 6 (4), 63, 2017 | 26 | 2017 |
| Targeting the kinase insert loop of PERK selectively modulates PERK signaling without systemic toxicity in mice DT Hughes, M Halliday, HL Smith, NC Verity, C Molloy, H Radford, ... Science signaling 13 (644), eabb4749, 2020 | 13 | 2020 |
| Trazodone rescues dysregulated synaptic and mitochondrial nascent proteomes in prion neurodegeneration H Albert-Gasco, HL Smith, B Alvarez-Castelao, D Swinden, M Halliday, ... Brain 147 (2), 649-664, 2024 | 7 | 2024 |
| Translating translation in Down syndrome M Halliday, GR Mallucci Science 366 (6467), 797-798, 2019 | 4 | 2019 |
| Reply: Trazodone to change the risk of neurodegeneration: bedside to bench M Halliday, GR Mallucci Brain 140 (8), e48-e48, 2017 | 2 | 2017 |
| Trazodone rescues dysregulated synaptic and mitochondrial nascent translatomes in prion neurodegeneration H Albert-Gasco, HL Smith, B Alvarez-Castelao, D Swinden, M Halliday, ... BioRxiv, 2023.06. 05.543732, 2023 | 1 | 2023 |
| Fine-tuning PERK signaling for neuroprotection (vol 142, pg 812, 2017) M Halliday, D Hughes, GR Mallucci JOURNAL OF NEUROCHEMISTRY 149 (5), 699-699, 2019 | | 2019 |
| Targeting the unfolded protein response as a potential therapeutic in prion disease M Halliday University of Leicester, 2014 | | 2014 |
| Sustained translational repression by eIF2 alpha-P mediates prion neurodegeneration G Mallucci, J Moreno, H Radford, D Peretti, J Steinert, N Verity, MG Martin, ... PRION 6, 8-8, 2012 | | 2012 |
| Corrigendum: Sustained translational repression by eIF2 alpha-P mediates prion neurodegeneration (vol 485, pg 507, 2012) JA Moreno, H Radford, D Peretti, JR Steinert, N Verity, M Guerra Martin, ... Nature Publishing Group 511 (7509), 0 | | |
