2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity PL Sulkowski, CD Corso, ND Robinson, SE Scanlon, KR Purshouse, ... Science translational medicine 9 (375), eaal2463, 2017 | 543 | 2017 |
m6A modification prevents formation of endogenous double-stranded RNAs and deleterious innate immune responses during hematopoietic development Y Gao, R Vasic, Y Song, R Teng, C Liu, R Gbyli, G Biancon, R Nelakanti, ... Immunity 52 (6), 1007-1021. e8, 2020 | 146 | 2020 |
Nanoscale subcellular architecture revealed by multicolor three-dimensional salvaged fluorescence imaging Y Zhang, LK Schroeder, MD Lessard, P Kidd, J Chung, Y Song, ... Nature methods 17 (2), 225-231, 2020 | 108 | 2020 |
A highly efficient and faithful MDS patient-derived xenotransplantation model for pre-clinical studies Y Song, A Rongvaux, A Taylor, T Jiang, T Tebaldi, K Balasubramanian, ... Nature communications 10 (1), 366, 2019 | 82 | 2019 |
SRSF2 mutations drive oncogenesis by activating a global program of aberrant alternative splicing in hematopoietic cells Y Liang, T Tebaldi, K Rejeski, P Joshi, G Stefani, A Taylor, Y Song, ... Leukemia 32 (12), 2659-2671, 2018 | 81 | 2018 |
Peripheral blood CD34+ cells efficiently engraft human cytokine knock-in mice Y Saito, JM Ellegast, A Rafiei, Y Song, D Kull, M Heikenwalder, ... Blood, The Journal of the American Society of Hematology 128 (14), 1829-1833, 2016 | 81 | 2016 |
Time series analyses of hand, foot and mouth disease integrating weather variables Y Song, F Wang, B Wang, S Tao, H Zhang, S Liu, O Ramirez, Q Zeng PloS one 10 (3), e0117296, 2015 | 50 | 2015 |
Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies G Biancon, P Joshi, JT Zimmer, T Hunck, Y Gao, MD Lessard, ... Molecular cell 82 (6), 1107-1122. e7, 2022 | 46 | 2022 |
Small interfering RNA targeting NF-κB attenuates lipopolysaccharide-induced acute lung injury in rats N Li, Y Song, W Zhao, T Han, S Lin, O Ramirez, L Liang BMC physiology 16, 1-8, 2016 | 45 | 2016 |
Helicobacter pylori-induced NAT10 stabilizes MDM2 mRNA via RNA acetylation to facilitate gastric cancer progression M Deng, L Zhang, W Zheng, J Chen, N Du, M Li, W Chen, Y Huang, ... Journal of Experimental & Clinical Cancer Research 42 (1), 9, 2023 | 39 | 2023 |
Combined liver–cytokine humanization comes to the rescue of circulating human red blood cells Y Song, L Shan, R Gbyli, W Liu, T Strowig, A Patel, X Fu, X Wang, ML Xu, ... Science 371 (6533), 1019-1025, 2021 | 27 | 2021 |
In vivo anti-tumor effect of PARP inhibition in IDH1/2 mutant MDS/AML resistant to targeted inhibitors of mutant IDH1/2 R Gbyli, Y Song, W Liu, Y Gao, G Biancon, NS Chandhok, X Wang, X Fu, ... Leukemia 36 (5), 1313-1323, 2022 | 15 | 2022 |
Humanized mice as preclinical models for myeloid malignancies R Gbyli, Y Song, S Halene Biochemical Pharmacology 174, 113794, 2020 | 15 | 2020 |
Targeting the EIF2AK1 Signaling Pathway Rescues Red Blood Cell Production in SF3B1-Mutant Myelodysplastic Syndromes With Ringed Sideroblasts V Adema, F Ma, R Kanagal-Shamanna, N Thongon, G Montalban-Bravo, ... Blood cancer discovery 3 (6), 554-567, 2022 | 13 | 2022 |
Association Between NR3C1 Mutations and Glucocorticoid Resistance in Children With Acute Lymphoblastic Leukemia H Liu, Z Li, F Qiu, C Li, X Lin, Y He, M Qian, Y Song, H Zhang Frontiers in Pharmacology 12, 634956, 2021 | 11 | 2021 |
ALKBH5 modulates hematopoietic stem and progenitor cell energy metabolism through m6A modification-mediated RNA stability control Y Gao, JT Zimmer, R Vasic, C Liu, R Gbyli, SJ Zheng, A Patel, W Liu, Z Qi, ... Cell Reports 42 (10), 2023 | 9 | 2023 |
Selective inhibition of MCL1 overcomes venetoclax resistance in a murine model of myelodysplastic syndromes MA Fischer, Y Song, MP Arrate, R Gbyli, MT Villaume, BN Smith, ... Haematologica 108 (2), 522, 2023 | 6 | 2023 |
Effect of UCP2-siRNA on inflammatory response of cardiomyocytes induced by septic serum ZJ Chen, YB Song, HL Wang, Y Wang, JJ Lv, D Che, QY Zeng Zhongguo Dang dai er ke za zhi= Chinese Journal of Contemporary Pediatrics …, 2014 | 4 | 2014 |
Chemo-free maintenance therapy in adult T-cell acute lymphoblastic leukemia: A case report and literature review Y Song, S Chen, C Liu, L Chen, W Wang, B Wu, Y Liang Frontiers in Pharmacology 14, 1051305, 2023 | 3 | 2023 |
Effects of NRAS Mutations on Leukemogenesis and Targeting of Children With Acute Lymphoblastic Leukemia J Qian, Z Li, K Pei, Z Li, C Li, M Yan, M Qian, Y Song, H Zhang, Y He Frontiers in Cell and Developmental Biology 10, 712484, 2022 | 3 | 2022 |