mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability L Schoenmaker, D Witzigmann, JA Kulkarni, R Verbeke, G Kersten, ... International journal of pharmaceutics 601, 120586, 2021 | 919 | 2021 |
The dawn of mRNA vaccines: The COVID-19 case R Verbeke, I Lentacker, SC De Smedt, H Dewitte Journal of Controlled Release 333, 511-520, 2021 | 379 | 2021 |
Three decades of messenger RNA vaccine development R Verbeke, I Lentacker, SC De Smedt, H Dewitte Nano Today 28, 100766, 2019 | 315 | 2019 |
Innate immune mechanisms of mRNA vaccines R Verbeke, MJ Hogan, K Loré, N Pardi Immunity 55 (11), 1993-2005, 2022 | 132 | 2022 |
Co-delivery of nucleoside-modified mRNA and TLR agonists for cancer immunotherapy: Restoring the immunogenicity of immunosilent mRNA R Verbeke, I Lentacker, L Wayteck, K Breckpot, M Van Bockstal, ... Journal of Controlled Release 266, 287-300, 2017 | 127 | 2017 |
Particle-mediated intravenous delivery of antigen mRNA results in strong antigen-specific T-cell responses despite the induction of type I interferon K Broos, K Van der Jeught, J Puttemans, C Goyvaerts, C Heirman, ... Molecular Therapy-Nucleic Acids 5, 2016 | 111 | 2016 |
Broadening the message: a nanovaccine co-loaded with messenger RNA and α-GalCer induces antitumor immunity through conventional and natural killer T cells R Verbeke, I Lentacker, K Breckpot, J Janssens, S Van Calenbergh, ... ACS nano 13 (2), 1655-1669, 2019 | 88 | 2019 |
Strategies for controlling the innate immune activity of conventional and self-amplifying mRNA therapeutics: Getting the message across AK Minnaert, H Vanluchene, R Verbeke, I Lentacker, SC De Smedt, ... Advanced drug delivery reviews 176, 113900, 2021 | 72 | 2021 |
Nanoparticle design to induce tumor immunity and challenge the suppressive tumor microenvironment H Dewitte, R Verbeke, K Breckpot, SC De Smedt, I Lentacker Nano Today 9 (6), 743-758, 2014 | 72 | 2014 |
mRNA in cancer immunotherapy: beyond a source of antigen L Van Hoecke, R Verbeke, H Dewitte, I Lentacker, K Vermaelen, ... Molecular cancer 20, 1-14, 2021 | 63 | 2021 |
Intracellular delivery of mRNA in adherent and suspension cells by vapor nanobubble photoporation L Raes, S Stremersch, JC Fraire, T Brans, G Goetgeluk, S De Munter, ... Nano-Micro Letters 12, 1-17, 2020 | 56 | 2020 |
mRNA encoding a bispecific single domain antibody construct protects against influenza A virus infection in mice L Van Hoecke, R Verbeke, D De Vlieger, H Dewitte, K Roose, ... Molecular Therapy-Nucleic Acids 20, 777-787, 2020 | 36 | 2020 |
Continuous freeze-drying of messenger RNA lipid nanoparticles enables storage at higher temperatures S Meulewaeter, G Nuytten, MHY Cheng, SC De Smedt, PR Cullis, ... Journal of Controlled Release 357, 149-160, 2023 | 28 | 2023 |
Immunopeptidomics-based design of mRNA vaccine formulations against Listeria monocytogenes RL Mayer, R Verbeke, C Asselman, I Aernout, A Gul, D Eggermont, ... Nature Communications 13 (1), 6075, 2022 | 25 | 2022 |
Choose your models wisely: how different murine bone marrow-derived dendritic cell protocols influence the success of nanoparticulate vaccines in vitro H Dewitte, R Verbeke, K Breckpot, RE Vandenbroucke, C Libert, ... Journal of Controlled Release 195, 138-146, 2014 | 20 | 2014 |
Tri-modal In vivo Imaging of Pancreatic Islets Transplanted Subcutaneously in Mice S Liang, K Louchami, B Holvoet, R Verbeke, CM Deroose, B Manshian, ... Molecular Imaging and Biology 20, 940-951, 2018 | 18 | 2018 |
Exciting times for lipid nanoparticles: How Canadian discoveries are enabling gene therapies MHY Cheng, CA Brimacombe, R Verbeke, PR Cullis Molecular pharmaceutics 19 (6), 1663-1668, 2022 | 11 | 2022 |
Challenges for labeling and longitudinal tracking of adoptively transferred autoreactive T lymphocytes in an experimental type-1 diabetes model S Saini, H Korf, S Liang, R Verbeke, B Manshian, K Raemdonck, ... Magnetic Resonance Materials in Physics, Biology and Medicine 32, 295-305, 2019 | 11 | 2019 |
Transport by circulating myeloid cells drives liposomal accumulation in inflamed synovium J Deprez, R Verbeke, S Meulewaeter, I Aernout, H Dewitte, T Decruy, ... Nature Nanotechnology 18 (11), 1341-1350, 2023 | 10 | 2023 |
Fluorine MR imaging probes dynamic migratory profiles of perfluorocarbon-loaded dendritic cells after streptozotocin-induced inflammation S Saini, AS Vanherwegen, S Liang, R Verbeke, H Korf, I Lentacker, ... Molecular Imaging and Biology 24 (2), 321-332, 2022 | 6 | 2022 |