The involvement of arginase and nitric oxide synthase in breast cancer development: arginase and NO synthase as therapeutic targets in cancer N Avtandilyan, H Javrushyan, G Petrosyan, A Trchounian BioMed research international 2018 (1), 8696923, 2018 | 45 | 2018 |
Antihyperglycemic activity of L-norvaline and L-arginine in high-fat diet and streptozotocin-treated male rats H Javrushyan, E Nadiryan, A Grigoryan, N Avtandilyan, A Maloyan Experimental and molecular pathology 126, 104763, 2022 | 19 | 2022 |
Anti-cancer effect of Rumex obtusifolius in combination with arginase/nitric oxide synthase inhibitors via downregulation of oxidative stress, inflammation, and polyamine synthesis M Ginovyan, H Javrushyan, G Petrosyan, B Kusznierewicz, ... The International Journal of Biochemistry & Cell Biology 158, 106396, 2023 | 15 | 2023 |
The potential therapeutic effect of NG-hydroxy-nor-L-arginine in 7, 12-dimethylbenz (a) anthracene-induced breast cancer in rats N Avtandilyan, H Javrushyan, A Mamikonyan, A Grigoryan, A Trchounian Experimental and molecular pathology 111, 104316, 2019 | 14 | 2019 |
Screening revealed the strong cytotoxic activity of Alchemilla smirnovii and Hypericum alpestre ethanol extracts on different cancer cell lines M Ginovyan, S Hovhannisyan, H Javrushyan, G Sevoyan, Z Karabekian, ... AIMS Biophysics 10 (1), 12-22, 2023 | 10 | 2023 |
Anti-cancer effect of in vivo inhibition of nitric oxide synthase in a rat model of breast cancer N Avtandilyan, H Javrushyan, M Ginovyan, A Karapetyan, A Trchounian Molecular and Cellular Biochemistry 478 (2), 261-275, 2023 | 7 | 2023 |
The effects of NO on the urea cycle pathway in short-term intermittent hypobaric hypoxia in rats H Javrushyan, N Avtandilyan, A Trchounian Respiratory Physiology & Neurobiology 285, 103598, 2021 | 7 | 2021 |
Hypericum alpestre extract exhibits in vitro and in vivo anticancer properties by regulating the cellular antioxidant system and metabolic pathway of L‐arginine M Ginovyan, H Javrushyan, H Karapetyan, I Koss‐Mikołajczyk, ... Cell Biochemistry and Function 42 (1), e3914, 2024 | 4 | 2024 |
RETRACTED ARTICLE: Inhibition of Tumor Progression by NG-Nitro-L-arginine Methyl Ester in 7,12- dimethylbenz(a)anthracene Induced Breast Cancer: Nitric … N Avtandilyan, H Javrushyan, A Karapetyan, A Trchounian Journal of Mammary Gland Biology & Neoplasia 24 (2), 2019 | 2 | 2019 |
EFFECT OF HYPOXIA ON THE ACTIVITY OF UREA CYCLE ENZYMES. HG Javrushyan, MH Khachatryan, MA Davtyan Electronic Journal of Natural Sciences 23 (2), 2014 | 2 | 2014 |
5-fluorouracil and Rumex obtusifolius extract combination trigger A549 cancer cell apoptosis: uncovering PI3K/Akt inhibition by in vitro and in silico approaches M Ginovyan, H Javrushyan, S Hovhannisyan, E Nadiryan, G Sevoyan, ... Scientific Reports 14 (1), 14676, 2024 | 1 | 2024 |
REGULATORY EFFECTS OF $ RUMEX~ OBTUSIFOLIUS $ AND $ HYPERICUM~ ALPESTRE $ EXTRACTS ON THE QUANTITY OF IL-2 IN $ IN~ VITRO $ AND $ IN~ VIVO $ CANCER MODELS SM Hovhannisyan, MV Qocharyan, HG Javrushyan, NV Avtandilyan Proceedings of the YSU B: Chemical and Biological Sciences 57 (3 (262)), 248-257, 2023 | 1 | 2023 |
The change of polyamines and nitric oxide quantities in human blood serum of prostate and bladder cancer H Javrushyan, N Avtandilyan, A Mamikonyan, A Trchounian Հայաստանի կենսաբանական հանդես 69 (1), 125-132, 2017 | 1 | 2017 |
Elucidating the Impact of Hypericum alpestre Extract and L-NAME on the PI3K/Akt Signaling Pathway in A549 Lung Adenocarcinoma Cells H Javrushyan, M Ginovyan, G Petrosyan, M Qocharyan, T Harutyunyan, ... bioRxiv, 2024.05. 02.592167, 2024 | | 2024 |
Royal Jelly–Mediated Silver Nanoparticles Show Promising Anticancer Effect on HeLa and A549 Cells Through Modulation of the VEGFa/PI3K/Akt/MMP‐2 Pathway M Kocharyan, S Marutyan, E Nadiryan, M Ginovyan, H Javrushyan, ... Applied Organometallic Chemistry, e7726, 2024 | | 2024 |
Hypericum alpestre extract exhibits in vitro and in vivo anticancer properties by regulating the cellular antioxidant system and metabolic pathway of L-arginine N Avtandilyan, M Ginovyan, H Javrushyan, H Karapetyan, ... | | 2023 |
Evaluation of immunostimulatory effect of combination of herbal extracts and chemotherapeutic drugs by quantitative alteration of interleukin-2 H Javrushyan, G Sevoyan, M Ginovyan, Z Karabekian, N Avtandilyan FEBS OPEN BIO 12, 96-96, 2022 | | 2022 |
Upregulation of nitric oxide quantity by L-norvaline and L-arginine in high-fat diet and streptozotocin-treated male rats E Nadiryan, H Javrushyan, N Avtandilyan, A Maloyan FEBS OPEN BIO 12, 142-142, 2022 | | 2022 |
New therapeutic approach in breast anticancer treatment using a combination of Rumex obtusifolius extract and L-arginine pathway inhibitors N Avtandilyan, H Javrushyan, A Karapetyan, M Ginovyan FEBS OPEN BIO 12, 105-105, 2022 | | 2022 |
Suppression of tumor progression by arginase and NO-synthase combined inhibition in 7, 12-dimethylbenz (a) anthracene-induced breast cancer in rats A Mamikonyan, H Javrushyan, N Avtandilyan, A Trchounian Febs Open Bio 11, 413-413, 2021 | | 2021 |