Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance V Barbier, J Erbani, C Fiveash, JM Davies, J Tay, MR Tallack, J Lowe, ... Nature communications 11 (1), 2042, 2020 | 139 | 2020 |
Cellular players of hematopoietic stem cell mobilization in the bone marrow niche J Tay, JP Levesque, IG Winkler International journal of hematology 105, 129-140, 2017 | 109 | 2017 |
Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells SW Lukowski, J Patel, SB Andersen, SL Sim, HY Wong, J Tay, I Winkler, ... Cell reports 27 (9), 2748-2758. e3, 2019 | 102 | 2019 |
Increased lipid metabolism impairs NK cell function and mediates adaptation to the lymphoma environment T Kobayashi, PY Lam, H Jiang, K Bednarska, R Gloury, V Murigneux, ... Blood, The Journal of the American Society of Hematology 136 (26), 3004-3017, 2020 | 91 | 2020 |
Acute myeloid leukemia chemo-resistance is mediated by E-selectin receptor CD162 in bone marrow niches J Erbani, J Tay, V Barbier, JP Levesque, IG Winkler Frontiers in cell and developmental biology 8, 668, 2020 | 43 | 2020 |
Addition of interleukin-2 overcomes resistance to neoadjuvant CTLA4 and PD1 blockade in ex vivo patient tumors P Kaptein, C Jacoberger-Foissac, P Dimitriadis, P Voabil, M de Bruijn, ... Science translational medicine 14 (642), eabj9779, 2022 | 23 | 2022 |
Imaging flow cytometry reveals that granulocyte colony-stimulating factor treatment causes loss of erythroblastic islands in the mouse bone marrow J Tay, K Bisht, C McGirr, SM Millard, AR Pettit, IG Winkler, JP Levesque Experimental hematology 82, 33-42, 2020 | 19 | 2020 |
Bacterial lipopolysaccharides suppress erythroblastic islands and erythropoiesis in the bone marrow in an extrinsic and G-CSF-, IL-1-, and TNF-independent manner K Bisht, J Tay, RN Wellburn, C McGirr, W Fleming, B Nowlan, V Barbier, ... Frontiers in immunology 11, 583550, 2020 | 18 | 2020 |
Endothelial E‑selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche‑mediated chemoresistance. Nat Commun. 2020 V Barbier, J Erbani, C Fiveash, JM Davies, J Tay, MR Tallack, J Lowe, ... DOI: https://doi. org/10.1038/s41467-020-15817-5, 2042, 0 | 8 | |
Blocking vascular Niche E-selectin dampens AML Stem cell regeneration/survival potential in vivo by inhibiting MAPK/ERK and PI3K/AKT signalling pathways IG Winkler, V Barbier, J Tay, JP Levesque, JL Magnani, CE Fiveash, ... Blood 134, 2657, 2019 | 6 | 2019 |
Vascular E-Selectin Mediates Chemo-Resistance in Acute Myeloid Leukemia Initiating Cells Via Canonical Receptors PSGL-1 (CD162) and Hcell (CD44) and AKT Signaling IG Winkler, JM Erbani, V Barbier, JM Davies, J Tay, CE Fiveash, J Lowe, ... Blood, The Journal of the American Society of Hematology 130 (Suppl_1), 793-793, 2017 | 4 | 2017 |
Prostacyclin is an endosteal bone marrow niche component and its clinical analog iloprost protects hematopoietic stem cell potential during stress J Tay, V Barbier, FM Helwani, GR Price, JP Levesque, IG Winkler Stem Cells 39 (11), 1532-1545, 2021 | 3 | 2021 |
Imaging flow cytometry reveals that G-CSF treatment causes loss of erythroblastic islands in the mouse bone marrow J Tay, K Bisht, C McGirr, S Millard, AR Pettit, IG Winkler, JP Levesque, ... Exp Hematol 82, 33-42, 2020 | 2 | 2020 |
Osteonecrosis of the femoral head: Can arthroplasty be avoided—a brief review of common interventions TA Einhorn, AA Anoushiravani, KK Chen, T Draper, T Tsismenakis, R Iorio The Journal of Hip Surgery 3 (03), 142-150, 2019 | 2 | 2019 |
Vascular E-Selectin Acts As a Gatekeeper Inducing Commitment and Loss of Self-Renewal in HSC Transmigrating through the Marrow Vasculature IG Winkler, V Barbier, J Lowe, J Tay, JL Magnani, P Marlton, AK Mills, ... Blood, The Journal of the American Society of Hematology 132 (Supplement 1 …, 2018 | 1 | 2018 |
Vascular niche E-selectin promotes acute myeloid leukemia resistance to chemotherapy via its receptors CD44 and CD162 J Erbani, V Barbier, J Lowe, J Tay, JP Levesque, I Winkler Experimental Hematology 64, S63, 2018 | 1 | 2018 |
Prostaglandin I2 is produced in the endosteal region of the bone marrow and protects haematopoietic stem cell from irradiation stress J Tay, JP Levesque, F Helwani, G Price, V Barbier, B Nowlan, I Winkler Experimental Hematology 44 (9), S102-S103, 2016 | 1 | 2016 |
Imaging Flow Cytometric Analysis of Primary Bone Marrow Erythroblastic Islands J Tay, K Bisht, IG Winkler, JP Levesque Spectral and Imaging Cytometry: Methods and Protocols, 43-61, 2023 | | 2023 |
Check for updates Chapter 3 Imaging Flow Cytometric Analysis of Primary Bone Marrow Erythroblastic Islands Joshua Tay, Kavita Bisht, Ingrid G. Winkler, and Jean-Pierre Levesque E Islands, J Tay Spectral and Imaging Cytometry: Methods and Protocols 2635, 43, 2023 | | 2023 |
CD162 Is a Key E-Selectin Receptor Promoting Acute Myeloid Leukemia Chemo-Resistance in the Bone Marrow Niche JD Erbani, J Tay, V Barbier, JP Levesque, JL Magnani, IG Winkler Blood 134, 907, 2019 | | 2019 |