| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 11057 | 2021 |
| PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1 S Geisler, KM Holmström, D Skujat, FC Fiesel, OC Rothfuss, PJ Kahle, ... Nature cell biology 12 (2), 119-131, 2010 | 3166 | 2010 |
| Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes DJ Klionsky, H Abeliovich, P Agostinis, DK Agrawal, G Aliev, DS Askew, ... Autophagy 4 (2), 151-175, 2008 | 2804 | 2008 |
| The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations S Geisler, KM Holmström, A Treis, D Skujat, SS Weber, FC Fiesel, ... Autophagy 6 (7), 871-878, 2010 | 387 | 2010 |
| Autophagy in Parkinson's disease X Hou, JO Watzlawik, FC Fiesel, W Springer Journal of molecular biology 432 (8), 2651-2672, 2020 | 305 | 2020 |
| Knockdown of transactive response DNA‐binding protein (TDP‐43) downregulates histone deacetylase 6 FC Fiesel, A Voigt, SS Weber, C Van den Haute, A Waldenmaier, ... The EMBO journal 29 (1), 209-221, 2010 | 288 | 2010 |
| Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice M Yue, KM Hinkle, P Davies, E Trushina, FC Fiesel, TA Christenson, ... Neurobiology of disease 78, 172-195, 2015 | 267 | 2015 |
| PINK1, Parkin, and mitochondrial quality control: what can we learn about Parkinson’s disease pathobiology? D Truban, X Hou, TR Caulfield, FC Fiesel, W Springer Journal of Parkinson's disease 7 (1), 13-29, 2017 | 235 | 2017 |
| Regulation of PINK1-Parkin-mediated mitophagy W Springer, PJ Kahle Autophagy 7 (3), 266-278, 2011 | 199 | 2011 |
| PINK1 primes Parkin-mediated ubiquitination of PARIS in dopaminergic neuronal survival Y Lee, DA Stevens, SU Kang, H Jiang, YI Lee, HS Ko, LA Scarffe, ... Cell reports 18 (4), 918-932, 2017 | 192 | 2017 |
| Regulation of the myosin-directed chaperone UNC-45 by a novel E3/E4-multiubiquitylation complex in C. elegans T Hoppe, G Cassata, JM Barral, W Springer, AH Hutagalung, HF Epstein, ... Cell 118 (3), 337-349, 2004 | 172 | 2004 |
| (Patho‐) physiological relevance of PINK 1‐dependent ubiquitin phosphorylation FC Fiesel, M Ando, R Hudec, AR Hill, M Castanedes‐Casey, TR Caulfield, ... EMBO reports 16 (9), 1114-1130, 2015 | 169 | 2015 |
| Alpha-synuclein-induced mitochondrial dysfunction is mediated via a sirtuin 3-dependent pathway JH Park, JD Burgess, AH Faroqi, NN DeMeo, FC Fiesel, W Springer, ... Molecular neurodegeneration 15, 1-19, 2020 | 152 | 2020 |
| Heterozygous PINK1 p. G411S increases risk of Parkinson’s disease via a dominant-negative mechanism A Puschmann, FC Fiesel, TR Caulfield, R Hudec, M Ando, D Truban, ... Brain 140 (1), 98-117, 2017 | 143 | 2017 |
| miR-27a and miR-27b regulate autophagic clearance of damaged mitochondria by targeting PTEN-induced putative kinase 1 (PINK1) J Kim, FC Fiesel, KC Belmonte, R Hudec, WX Wang, C Kim, PT Nelson, ... Molecular neurodegeneration 11, 1-16, 2016 | 138 | 2016 |
| The AMPK–Parkin axis negatively regulates necroptosis and tumorigenesis by inhibiting the necrosome SB Lee, JJ Kim, SA Han, Y Fan, LS Guo, K Aziz, S Nowsheen, SS Kim, ... Nature cell biology 21 (8), 940-951, 2019 | 135 | 2019 |
| A Caenorhabditis elegans Parkin mutant with altered solubility couples α-synuclein aggregation to proteotoxic stress W Springer, T Hoppe, E Schmidt, R Baumeister Human molecular genetics 14 (22), 3407-3423, 2005 | 134 | 2005 |
| Age-and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body disease X Hou, FC Fiesel, D Truban, M Castanedes Casey, W Lin, AI Soto, P Tacik, ... Autophagy 14 (8), 1404-1418, 2018 | 115 | 2018 |
| Phosphorylation by PINK1 releases the UBL domain and initializes the conformational opening of the E3 ubiquitin ligase Parkin TR Caulfield, FC Fiesel, EL Moussaud-Lamodière, DFAR Dourado, ... PLoS computational biology 10 (11), e1003935, 2014 | 109 | 2014 |
| Parkin protects against tyrosinase‐mediated dopamine neurotoxicity by suppressing stress‐activated protein kinase pathways T Hasegawa, A Treis, N Patenge, FC Fiesel, W Springer, PJ Kahle Journal of neurochemistry 105 (5), 1700-1715, 2008 | 106 | 2008 |
