Sensitization of hypoxic tumors to radiation therapy using ultrasound-sensitive oxygen microbubbles JR Eisenbrey, R Shraim, JB Liu, J Li, M Stanczak, B Oeffinger, DB Leeper, ... International Journal of Radiation Oncology* Biology* Physics 101 (1), 88-96, 2018 | 107 | 2018 |
Cytosine base editing enables quadruple-edited allogeneic CART cells for T-ALL C Diorio, R Murray, M Naniong, L Barrera, A Camblin, J Chukinas, ... Blood, The Journal of the American Society of Hematology 140 (6), 619-629, 2022 | 61 | 2022 |
The unique disease course of children with very early onset-inflammatory bowel disease JR Kelsen, MA Conrad, N Dawany, T Patel, R Shraim, A Merz, K Maurer, ... Inflammatory bowel diseases 26 (6), 909-918, 2020 | 60 | 2020 |
Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction C Diorio, R Shraim, LA Vella, JR Giles, AE Baxter, DA Oldridge, ... Nature communications 12 (1), 7222, 2021 | 57 | 2021 |
Modulation of CD22 protein expression in childhood leukemia by pervasive splicing aberrations: implications for CD22-directed immunotherapies S Zheng, E Gillespie, AS Naqvi, KE Hayer, Z Ang, M Torres-Diz, ... Blood cancer discovery 3 (2), 103-115, 2022 | 36 | 2022 |
Comprehensive serum proteome profiling of cytokine release syndrome and immune effector cell–associated neurotoxicity syndrome patients with B-cell all receiving CAR t19 C Diorio, R Shraim, R Myers, EM Behrens, S Canna, H Bassiri, R Aplenc, ... Clinical Cancer Research 28 (17), 3804-3813, 2022 | 31 | 2022 |
Preserving the integrity of surfactant-stabilized microbubble membranes for localized oxygen delivery BE Oeffinger, P Vaidya, I Ayaz, R Shraim, JR Eisenbrey, MA Wheatley Langmuir 35 (31), 10068-10078, 2019 | 23 | 2019 |
High-throughput mutagenesis identifies mutations and RNA-binding proteins controlling CD19 splicing and CART-19 therapy resistance M Cortés-López, L Schulz, M Enculescu, C Paret, B Spiekermann, ... Nature Communications 13 (1), 5570, 2022 | 21 | 2022 |
Rational drug combinations with CDK4/6 inhibitors in acute lymphoblastic leukemia KL Bride, H Hu, A Tikhonova, TJ Fuller, TL Vincent, R Shraim, MM Li, ... Haematologica 107 (8), 1746, 2022 | 19 | 2022 |
Colonoids from patients with pediatric inflammatory bowel disease exhibit decreased growth associated with inflammation severity and durable upregulation of antigen … JR Kelsen, N Dawany, MA Conrad, TA Karakasheva, K Maurer, JM Wei, ... Inflammatory Bowel Diseases 27 (2), 256-267, 2021 | 14 | 2021 |
GPC2 antibody–drug conjugate reprograms the neuroblastoma immune milieu to enhance macrophage-driven therapies G Pascual-Pasto, B McIntyre, R Shraim, SN Buongervino, AK Erbe, ... Journal for ImmunoTherapy of Cancer 10 (12), 2022 | 11 | 2022 |
Surface and global proteome analyses identify ENPP1 and other surface proteins as actionable immunotherapeutic targets in Ewing sarcoma B Mooney, GL Negri, T Shyp, A Delaidelli, HF Zhang, SE Spencer Miko, ... Clinical Cancer Research 30 (5), 1022-1037, 2024 | 9 | 2024 |
Comprehensive genome characterization of childhood T-ALL links oncogene activation mechanism and subtypes to prognosis P Pölönen, A Elsayed, D Di Giacomo, L Montefiori, S Kimura, J Myers, ... Blood 140 (Supplement 1), 1727-1729, 2022 | 8 | 2022 |
Proteomic profiling of MIS-C patients reveals heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction C Diorio, R Shraim, LA Vella, JR Giles, AE Baxter, DA Oldridge, ... medRxiv, 2021.04. 13.21255439, 2021 | 7 | 2021 |
Mucosal invariant T cells are diminished in very early-onset inflammatory bowel disease Y Dou, K Maurer, M Conrad, T Patel, R Shraim, KE Sullivan, J Kelsen Journal of pediatric gastroenterology and nutrition 73 (4), 529-536, 2021 | 6 | 2021 |
S102: COMPREHENSIVE GENOME CHARACTERIZATION REVEALS NEW SUBTYPES AND MECHANISMS OF ONCOGENE DEREGULATION IN CHILDHOOD T-ALL P Pölönen, A Elsayed, L Montefiori, S Kimura, J Myers, D Hedges, J Xu, ... HemaSphere 6, 3-4, 2022 | 4 | 2022 |
The genomic basis of childhood T-lineage acute lymphoblastic leukemia C Mullighan, P Pölönen, D Di Giacomo, A Seffernick, A Elsayed, S Kimura, ... | 3 | 2023 |
A MYCN-independent mechanism mediating secretome reprogramming and metastasis in MYCN-amplified neuroblastoma HF Zhang, A Delaidelli, S Javed, B Turgu, T Morrison, CS Hughes, ... Science Advances 9 (34), eadg6693, 2023 | 3 | 2023 |
The genomic basis of childhood T-lineage acute lymphoblastic leukaemia P Pölönen, D Di Giacomo, AE Seffernick, A Elsayed, S Kimura, F Benini, ... Nature, 1-10, 2024 | 1 | 2024 |
Identification and targeting of treatment resistant progenitor populations in T-cell Acute Lymphoblastic Leukemia K Tan, J Xu, C Chen, T Vincent, P Pölönen, J Hu, S Yoshimura, W Yu, ... Research Square, 2023 | 1 | 2023 |