Two-photon imaging of lymphocyte motility and antigen response in intact lymph node MJ Miller, SH Wei, I Parker, MD Cahalan Science 296 (5574), 1869-1873, 2002 | 1401 | 2002 |
Calcium Dysregulation and Membrane Disruption as a Ubiquitous Neurotoxic Mechanism of Soluble Amyloid Oligomers*♦ A Demuro, E Mina, R Kayed, SC Milton, I Parker, CG Glabe Journal of Biological Chemistry 280 (17), 17294-17300, 2005 | 1291 | 2005 |
Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria C Cárdenas, RA Miller, I Smith, T Bui, J Molgó, M Müller, H Vais, ... Cell 142 (2), 270-283, 2010 | 1109 | 2010 |
Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells T Okada, MJ Miller, I Parker, MF Krummel, M Neighbors, SB Hartley, ... PLoS biology 3 (6), e150, 2005 | 766 | 2005 |
Imaging the Single Cell Dynamics of CD4+ T Cell Activation by Dendritic Cells in Lymph Nodes MJ Miller, O Safrina, I Parker, MD Cahalan The Journal of experimental medicine 200 (7), 847-856, 2004 | 649 | 2004 |
Autonomous T cell trafficking examined in vivo with intravital two-photon microscopy MJ Miller, SH Wei, MD Cahalan, I Parker Proceedings of the National Academy of Sciences 100 (5), 2604-2609, 2003 | 605 | 2003 |
Two-photon tissue imaging: seeing the immune system in a fresh light MD Cahalan, I Parker, SH Wei, MJ Miller Nature Reviews Immunology 2 (11), 872-880, 2002 | 562 | 2002 |
T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node MJ Miller, AS Hejazi, SH Wei, MD Cahalan, I Parker Proceedings of the National Academy of Sciences 101 (4), 998-1003, 2004 | 541 | 2004 |
Fluorescence microscopy MJ Sanderson, I Smith, I Parker, MD Bootman Cold Spring Harbor Protocols 2014 (10), pdb. top071795, 2014 | 515 | 2014 |
The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers A Penna, A Demuro, AV Yeromin, SL Zhang, O Safrina, I Parker, ... Nature 456 (7218), 116-120, 2008 | 508 | 2008 |
Calcium signaling and amyloid toxicity in Alzheimer disease A Demuro, I Parker, GE Stutzmann Journal of Biological Chemistry 285 (17), 12463-12468, 2010 | 494 | 2010 |
Chloride current induced by injection of calcium into Xenopus oocytes. R Miledi, I Parker The Journal of physiology 357 (1), 173-183, 1984 | 464 | 1984 |
Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo MG Sanna, SK Wang, PJ Gonzalez-Cabrera, A Don, D Marsolais, ... Nature chemical biology 2 (8), 434-441, 2006 | 459 | 2006 |
Quantal puffs of intracellular Ca2+ evoked by inositol trisphosphate in Xenopus oocytes. Y Yao, J Choi, I Parker The Journal of physiology 482 (3), 533-553, 1995 | 429 | 1995 |
Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer's disease mice GE Stutzmann, I Smith, A Caccamo, S Oddo, FM LaFerla, I Parker Journal of Neuroscience 26 (19), 5180-5189, 2006 | 386 | 2006 |
SERCA pump activity is physiologically regulated by presenilin and regulates amyloid β production KN Green, A Demuro, Y Akbari, BD Hitt, IF Smith, I Parker, FM LaFerla The Journal of cell biology 181 (7), 1107-1116, 2008 | 351 | 2008 |
Choreography of cell motility and interaction dynamics imaged by two-photon microscopy in lymphoid organs MD Cahalan, I Parker Annu. Rev. Immunol. 26, 585-626, 2008 | 340 | 2008 |
Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered … GE Stutzmann, A Caccamo, FM LaFerla, I Parker Journal of Neuroscience 24 (2), 508-513, 2004 | 330 | 2004 |
Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses SH Wei, H Rosen, MP Matheu, MG Sanna, SK Wang, E Jo, CH Wong, ... Nature immunology 6 (12), 1228-1235, 2005 | 327 | 2005 |
A continuum of InsP3‐mediated elementary Ca2+ signalling events in Xenopus oocytes XP Sun, N Callamaras, JS Marchant, I Parker The Journal of Physiology 509 (1), 67-80, 1998 | 299 | 1998 |