Involvement of AMPK, IKβα-NFκB and eNOS in the sildenafil anti-inflammatory mechanism in a demyelination model AKS Nunes, C Raposo, SWS Rocha, KP de Sousa Barbosa, ... Brain research 1627, 119-133, 2015 | 88 | 2015 |
Sildenafil (Viagra®) down regulates cytokines and prevents demyelination in a cuprizone-induced MS mouse model AK de Santana Nunes, C Rapôso, RL de Almeida Luna, ... Cytokine 60 (2), 540-551, 2012 | 77 | 2012 |
Sildenafil (Viagra) protective effects on neuroinflammation: the role of iNOS/NO system in an inflammatory demyelination model C Raposo, AKS Nunes, RLA Luna, SMR Araújo, MA da Cruz-Höfling, ... Mediators of Inflammation 2013 (1), 321460, 2013 | 75 | 2013 |
CAR-T cells: Early successes in blood cancer and challenges in solid tumors H Dana, GM Chalbatani, SA Jalali, HR Mirzaei, SA Grupp, ER Suarez, ... Acta Pharmaceutica Sinica B 11 (5), 1129-1147, 2021 | 67 | 2021 |
Role of iNOS-NO-cGMP signaling in modulation of inflammatory and myelination processes C Rapôso, RL de Almeida Luna, AKS Nunes, R Thomé, CA Peixoto Brain Research Bulletin 104, 60-73, 2014 | 60 | 2014 |
Artemether and lumefantrine dissolving microneedle patches with improved pharmacokinetic performance and antimalarial efficacy in mice infected with Plasmodium yoelii F Volpe-Zanutto, LT Ferreira, AD Permana, M Kirkby, AJ Paredes, ... Journal of controlled release 333, 298-315, 2021 | 59 | 2021 |
The hippo tumor suppressor pathway (yap/taz/tead/mst/lats) and egfr-ras-raf-mek in cancer metastasis MR Zinatizadeh, SR Miri, PK Zarandi, GM Chalbatani, C Rapôso, ... Genes & diseases 8 (1), 48-60, 2021 | 55 | 2021 |
Scorpion and spider venoms in cancer treatment: state of the art, challenges, and perspectives C Rapôso Journal of clinical and translational research 3 (2), 233, 2017 | 50 | 2017 |
Acute blood–brain barrier permeabilization in rats after systemic Phoneutria nigriventer venom C Rapôso, GM Zago, GH da Silva, MA da Cruz Höfling Brain research 1149, 18-29, 2007 | 41 | 2007 |
Phosphodiesterase-5 inhibition promotes remyelination by MCP-1/CCR-2 and MMP-9 regulation in a cuprizone-induced demyelination model AK de Santana Nunes, C Rapôso, WH de Oliveira, R Thomé, L Verinaud, ... Experimental Neurology 275, 143-153, 2016 | 35 | 2016 |
Effect of Phoneutria nigriventer Venom on the Expression of Junctional Protein and P-gp Efflux Pump Function in the Blood–Brain Barrier C Rapôso, PAM Odorissi, ALR Oliveira, H Aoyama, CV Ferreira, ... Neurochemical research 37, 1967-1981, 2012 | 33 | 2012 |
Effect of diethylcarbamazine on chronic hepatic inflammation induced by alcohol in C57BL/6 mice SWS Rocha, BS Silva, FO dos Santos Gomes, AKS e Silva, C Raposo, ... European Journal of Pharmacology 689 (1-3), 194-203, 2012 | 29 | 2012 |
Neuroinflammation and astrocytic reaction in the course of Phoneutria nigriventer (armed-spider) blood–brain barrier (BBB) opening MA da Cruz-Höfling, C Rapôso, L Verinaud, GM Zago Neurotoxicology 30 (4), 636-646, 2009 | 26 | 2009 |
Sildenafil (Viagra®) prevents and restores LPS-induced inflammation in astrocytes AK de Santana Nunes, C Rapôso, U Björklund, MA da Cruz-Höfling, ... Neuroscience Letters 630, 59-65, 2016 | 23 | 2016 |
c-FOS and n-NOS reactive neurons in response to circulating Phoneutria nigriventer spider venom MA da Cruz-Höfling, GM Zago, LL Melo, C Rapôso Brain research bulletin 73 (1-3), 114-126, 2007 | 22 | 2007 |
Expression of VEGF and Flk-1 and Flt-1 Receptors during Blood-Brain Barrier (BBB) Impairment Following Phoneutria nigriventer Spider Venom Exposure MCP Mendonça, ES Soares, LM Stávale, C Rapôso, A Coope, ... Toxins 5 (12), 2572-2588, 2013 | 20 | 2013 |
Effect of new thiazolidine derivatives LPSF/GQ-02 and LPSF/GQ-16 on atherosclerotic lesions in LDL receptor-deficient mice (LDLR−/−) AKS e Silva, DOC Torres, SWS Rocha, FO dos Santos Gomes, ... Cardiovascular Pathology 22 (1), 81-90, 2013 | 18 | 2013 |
Spider venom administration impairs glioblastoma growth and modulates immune response in a non-clinical model AP Bonfanti, N Barreto, J Munhoz, M Caballero, G Cordeiro, ... Scientific reports 10 (1), 5876, 2020 | 15 | 2020 |
Triggering of Protection Mechanism against Phoneutria nigriventer Spider Venom in the Brain C Raposo, PAM Odorissi, SF Savioli, RCR Hell, GF Simoes, ... PLoS One 9 (9), e107292, 2014 | 15 | 2014 |
Neuropharmacological effects of Phoneutria nigriventer venom on astrocytes C Raposo, U Björklund, E Kalapothakis, B Biber, MA da Cruz-Höfling, ... Neurochemistry international 96, 13-23, 2016 | 14 | 2016 |