Compatible-solute-supported periplasmic expression of functional recombinant proteins under stress conditions S Barth, M Huhn, B Matthey, A Klimka, EA Galinski, A Engert Applied and environmental microbiology 66 (4), 1572-1579, 2000 | 273 | 2000 |
A phase-I study of an anti-CD25 ricin A-chain immunotoxin (RFT5-SMPT-dgA) in patients with refractory Hodgkin's lymphoma A Engert, V Diehl, R Schnell, A Radszuhn, MT Hatwig, S Drillich, ... Blood, The Journal of the American Society of Hematology 89 (2), 403-410, 1997 | 205 | 1997 |
Human anti-CD30 recombinant antibodies by guided phage antibody selection using cell panning A Klimka, B Matthey, RC Roovers, S Barth, JW Arends, A Engert, ... British journal of cancer 83 (2), 252-260, 2000 | 190 | 2000 |
Cell-specific induction of apoptosis by rationally designed bivalent aptamer-siRNA transcripts silencing eukaryotic elongation factor 2 U Wullner, I Neef, A Eller, M Kleines, MK Tur, S Barth Current cancer drug targets 8 (7), 554-565, 2008 | 169 | 2008 |
CD64: an attractive immunotherapeutic target for M1-type macrophage mediated chronic inflammatory diseases OA Akinrinmade, S Chetty, AK Daramola, M Islam, T Thepen, S Barth Biomedicines 5 (3), 56, 2017 | 132 | 2017 |
Ki-4 (scFv)–ETA′, a new recombinant anti-CD30 immunotoxin with highly specific cytotoxic activity against disseminated Hodgkin tumors in SCID mice S Barth, M Huhn, B Matthey, S Tawadros, R Schnell, T Schinköthe, ... Blood, The Journal of the American Society of Hematology 95 (12), 3909-3914, 2000 | 132 | 2000 |
Principles of immunotherapy: implications for treatment strategies in cancer and infectious diseases K Naran, T Nundalall, S Chetty, S Barth Frontiers in microbiology 9, 3158, 2018 | 130 | 2018 |
Control of mechanical pain hypersensitivity in mice through ligand-targeted photoablation of TrkB-positive sensory neurons R Dhandapani, CM Arokiaraj, FJ Taberner, P Pacifico, S Raja, L Nocchi, ... Nature communications 9 (1), 1640, 2018 | 125 | 2018 |
Human angiogenin fused to human CD30 ligand (Ang-CD30L) exhibits specific cytotoxicity against CD30-positive lymphoma M Huhn, S Sasse, MK Tur, B Matthey, T Schinköthe, SM Rybak, S Barth, ... Cancer research 61 (24), 8737-8742, 2001 | 117 | 2001 |
Granzyme B-H22 (scFv), a human immunotoxin targeting CD64 in acute myeloid leukemia of monocytic subtypes B Stahnke, T Thepen, M Stocker, R Rosinke, E Jost, R Fischer, MK Tur, ... Molecular cancer therapeutics 7 (9), 2924-2932, 2008 | 114 | 2008 |
Treatment of refractory Hodgkin's lymphoma patients with an anti-CD25 ricin A-chain immunotoxin R Schnell, E Vitetta, J Schindler, P Borchmann, S Barth, V Ghetie, K Hell, ... Leukemia 14 (1), 129-135, 2000 | 106 | 2000 |
Secretion of functional anti-CD30-angiogenin immunotoxins into the supernatant of transfected 293T-cells M Stöcker, MK Tur, S Sasse, A Krüßmann, S Barth, A Engert Protein expression and purification 28 (2), 211-219, 2003 | 103 | 2003 |
An anti-CD30 single-chain Fv selected by phage display and fused to Pseudomonas exotoxin A (Ki-4 (scFv)-ETA’) is a potent immunotoxin against a Hodgkin-derived cell line A Klimka, S Barth, B Matthey, RC Roovers, H Lemke, H Hansen, ... British journal of cancer 80 (8), 1214-1222, 1999 | 101 | 1999 |
Site-Specific, Covalent Labeling of Recombinant Antibody Fragments via Fusion to an Engineered Version of 6-O-Alkylguanine DNA Alkyltransferase F Kampmeier, M Ribbert, T Nachreiner, S Dembski, F Beaufils, A Brecht, ... Bioconjugate chemistry 20 (5), 1010-1015, 2009 | 98 | 2009 |
SNAP-tag technology mediates site specific conjugation of antibody fragments with a photosensitizer and improves target specific phototoxicity in tumor cells AF Hussain, F Kampmeier, V von Felbert, HF Merk, MK Tur, S Barth Bioconjugate chemistry 22 (12), 2487-2495, 2011 | 93 | 2011 |
Recombinant CD64-specific single chain immunotoxin exhibits specific cytotoxicity against acute myeloid leukemia cells MK Tur, M Huhn, T Thepen, M Stöcker, R Krohn, S Vogel, E Jost, ... Cancer research 63 (23), 8414-8419, 2003 | 89 | 2003 |
Targeted Delivery of Dendritic Polyglycerol–Doxorubicin Conjugates by scFv-SNAP Fusion Protein Suppresses EGFR+ Cancer Cell Growth AF Hussain, HR Krüger, F Kampmeier, T Weissbach, K Licha, F Kratz, ... Biomacromolecules 14 (8), 2510-2520, 2013 | 86 | 2013 |
Clinical trials with an anti-CD25 ricin A-chain experimental and immunotoxin (RFT5-SMPT-dgA) in Hodgkin's lymphoma R Schnell, E Vitetta, J Schindler, S Barth, U Winkler, P Borchmann, ... Leukemia & lymphoma 30 (5-6), 525-538, 1998 | 82 | 1998 |
Rapid optical imaging of EGF receptor expression with a single-chain antibody SNAP-tag fusion protein F Kampmeier, J Niesen, A Koers, M Ribbert, A Brecht, R Fischer, ... European journal of nuclear medicine and molecular imaging 37, 1926-1934, 2010 | 80 | 2010 |
Cloning, recombinant expression and biochemical characterisation of novel esterases from Bacillus sp. associated with the marine sponge Aplysina aerophoba A Karpushova, F Brümmer, S Barth, S Lange, RD Schmid Applied microbiology and biotechnology 67, 59-69, 2005 | 78 | 2005 |