| ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade J Shen, Z Ju, W Zhao, L Wang, Y Peng, Z Ge, ZD Nagel, J Zou, C Wang, ... Nature medicine 24 (5), 556-562, 2018 | 438 | 2018 |
| Adaptive mutability of colorectal cancers in response to targeted therapies M Russo, G Crisafulli, A Sogari, NM Reilly, S Arena, S Lamba, A Bartolini, ... Science 366 (6472), 1473-1480, 2019 | 345 | 2019 |
| WRN helicase is a synthetic lethal target in microsatellite unstable cancers EM Chan, T Shibue, JM McFarland, B Gaeta, M Ghandi, N Dumont, ... Nature 568 (7753), 551-556, 2019 | 290 | 2019 |
| Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis ZD Nagel, CM Margulies, IA Chaim, SK McRee, P Mazzucato, A Ahmad, ... Proceedings of the National Academy of Sciences 111 (18), E1823-E1832, 2014 | 139 | 2014 |
| Minor changes in expression of the mismatch repair protein MSH2 exert a major impact on glioblastoma response to temozolomide JL McFaline-Figueroa, CJ Braun, M Stanciu, ZD Nagel, P Mazzucato, ... Cancer research 75 (15), 3127-3138, 2015 | 136 | 2015 |
| DNA repair capacity in multiple pathways predicts chemoresistance in glioblastoma multiforme ZD Nagel, GJ Kitange, SK Gupta, BA Joughin, IA Chaim, P Mazzucato, ... Cancer research 77 (1), 198-206, 2017 | 125 | 2017 |
| Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death JH Houl, Z Ye, CA Brosey, LPF Balapiti-Modarage, S Namjoshi, A Bacolla, ... Nature communications 10 (1), 5654, 2019 | 93 | 2019 |
| Inter-individual variation in DNA repair capacity: a need for multi-pathway functional assays to promote translational DNA repair research ZD Nagel, IA Chaim, LD Samson DNA repair 19, 199-213, 2014 | 84 | 2014 |
| In vivo measurements of interindividual differences in DNA glycosylases and APE1 activities IA Chaim, ZD Nagel, JJ Jordan, P Mazzucato, LD Samson Proceedings of the National Academy of Sciences 114 (48), E10379-E10388, 2017 | 52 | 2017 |
| The CHD6 chromatin remodeler is an oxidative DNA damage response factor S Moore, ND Berger, MS Luijsterburg, CG Piett, FKT Stanley, ... Nature communications 10 (1), 241, 2019 | 50 | 2019 |
| Sodium sulfide selectively induces oxidative stress, DNA damage, and mitochondrial dysfunction and radiosensitizes glioblastoma (GBM) cells. AY Xiao, MR Maynard, CG Piett, ZD Nagel, JS Alexander, CG Kevil, ... Redox Biology 26, 101220, 2019 | 40 | 2019 |
| EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair AE Koyen, MZ Madden, D Park, EV Minten, P Kapoor-Vazirani, E Werner, ... Oncogene 39 (25), 4798-4813, 2020 | 38 | 2020 |
| Modelling Chlamydia and HPV co-infection in patient-derived ectocervix organoids reveals distinct cellular reprogramming S Koster, RK Gurumurthy, N Kumar, PG Prakash, J Dhanraj, S Bayer, ... Nature communications 13 (1), 1030, 2022 | 37 | 2022 |
| Defective base excision repair in the response to DNA damaging agents in triple negative breast cancer KJ Lee, CG Piett, JF Andrews, E Mann, ZD Nagel, NR Gassman PLoS One 14 (10), e0223725, 2019 | 35 | 2019 |
| Exploiting DNA repair defects in triple negative breast cancer to improve cell killing KJ Lee, E Mann, G Wright, CG Piett, ZD Nagel, NR Gassman Therapeutic Advances in Medical Oncology 12, 1758835920958354, 2020 | 34 | 2020 |
| Fluorescence sheds light on DNA damage, DNA repair, and mutations NA Owiti, ZD Nagel, BP Engelward Trends in cancer 7 (3), 240-248, 2021 | 25 | 2021 |
| Fluorogenic real-time reporters of DNA repair by MGMT, a clinical predictor of antitumor drug response AA Beharry, ZD Nagel, LD Samson, ET Kool PLoS One 11 (4), e0152684, 2016 | 25 | 2016 |
| Irradiation induces epithelial cell unjamming MJ O'Sullivan, JA Mitchel, A Das, S Koehler, H Levine, D Bi, ZD Nagel, ... Frontiers in Cell and Developmental Biology 8, 21, 2020 | 23 | 2020 |
| Towards precision prevention: technologies for identifying healthy individuals with high risk of disease ZD Nagel, BP Engelward, DJ Brenner, TJ Begley, RW Sobol, JH Bielas, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 800, 14-28, 2017 | 23 | 2017 |
| Nitric oxide induced S-nitrosation causes base excision repair imbalance MC Parrish, IA Chaim, ZD Nagel, SR Tannenbaum, LD Samson, ... DNA repair 68, 25-33, 2018 | 21 | 2018 |
