In vitro and in vivo experimental models for drug screening and development for Chagas disease AJ Romanha, SL Castro, MNC Soeiro, J Lannes-Vieira, I Ribeiro, ... Memórias do Instituto Oswaldo Cruz 105, 233-238, 2010 | 393 | 2010 |
Drug-induced cure drives conversion to a stable and protective CD8+ T central memory response in chronic Chagas disease JM Bustamante, LM Bixby, RL Tarleton Nature medicine 14 (5), 542-550, 2008 | 221 | 2008 |
In Vitro and In Vivo High-Throughput Assays for the Testing of Anti-Trypanosoma cruzi Compounds AMC Canavaci, JM Bustamante, AM Padilla, CM Perez Brandan, ... PLoS neglected tropical diseases 4 (7), e740, 2010 | 179 | 2010 |
CD8+ T cells in Trypanosoma cruzi infection AM Padilla, JM Bustamante, RL Tarleton Current opinion in immunology 21 (4), 385-390, 2009 | 178 | 2009 |
New, Combined, and Reduced Dosing Treatment Protocols Cure Trypanosoma cruzi Infection in Mice JM Bustamante, JM Craft, BD Crowe, SA Ketchie, RL Tarleton The Journal of infectious diseases 209 (1), 150-162, 2014 | 153 | 2014 |
Biomarkers of therapeutic responses in chronic Chagas disease: state of the art and future perspectives MJ Pinazo, MC Thomas, J Bustamante, IC Almeida, MC Lopez, J Gascon Memórias do Instituto Oswaldo Cruz 110, 422-432, 2015 | 101 | 2015 |
Rapid, selection-free, high-efficiency genome editing in protozoan parasites using CRISPR-Cas9 ribonucleoproteins LC Soares Medeiros, L South, D Peng, JM Bustamante, W Wang, ... MBio 8 (6), 10.1128/mbio. 01788-17, 2017 | 90 | 2017 |
Trypanosoma cruzi reinfections in mice determine the severity of cardiac damage JM Bustamante, HW Rivarola, AR Fernández, JE Enders, R Fretes, ... International journal for parasitology 32 (7), 889-896, 2002 | 90 | 2002 |
Potential new clinical therapies for Chagas disease JM Bustamante, RL Tarleton Expert review of clinical pharmacology 7 (3), 317-325, 2014 | 62 | 2014 |
Trypanoside, anti-tuberculosis, leishmanicidal, and cytotoxic activities of tetrahydrobenzothienopyrimidines JC Aponte, AJ Vaisberg, D Castillo, G Gonzalez, Y Estevez, J Arevalo, ... Bioorganic & medicinal chemistry 18 (8), 2880-2886, 2010 | 61 | 2010 |
Indeterminate Chagas’ disease: Trypanosoma cruzi strain and re-infection are factors involved in the progression of cardiopathy JM Bustamante, HW Rivarola, AR Fernández, JE Enders, R Fretes, ... Clinical science 104 (4), 415-420, 2003 | 55 | 2003 |
Reinfections and Trypanosoma cruzi strains can determine the prognosis of the chronic chagasic cardiopathy in mice JM Bustamante, M Novarese, HW Rivarola, MS Lo Presti, AR Fernández, ... Parasitology research 100, 1407-1410, 2007 | 50 | 2007 |
Treatment with benznidazole or thioridazine in the chronic phase of experimental Chagas disease improves cardiopathy JM Bustamante, MSL Presti, HW Rivarola, AR Fernández, JE Enders, ... International journal of antimicrobial agents 29 (6), 733-737, 2007 | 49 | 2007 |
Oral Exposure to Trypanosoma cruzi Elicits a Systemic CD8+ T Cell Response and Protection against Heterotopic Challenge MH Collins, JM Craft, JM Bustamante, RL Tarleton Infection and immunity 79 (8), 3397-3406, 2011 | 41 | 2011 |
Methodological advances in drug discovery for Chagas disease JM Bustamante, RL Tarleton Expert opinion on drug discovery 6 (6), 653-661, 2011 | 40 | 2011 |
A modified drug regimen clears active and dormant trypanosomes in mouse models of Chagas disease JM Bustamante, F Sanchez-Valdez, AM Padilla, B White, W Wang, ... Science translational medicine 12 (567), eabb7656, 2020 | 38 | 2020 |
Thioridazine treatment prevents cardiopathy in Trypanosoma cruzi infected mice MSL Presti, HW Rivarola, JM Bustamante, AR Fernández, JE Enders, ... International journal of antimicrobial agents 23 (6), 634-636, 2004 | 38 | 2004 |
Reaching for the Holy Grail: insights from infection/cure models on the prospects for vaccines for Trypanosoma cruziinfection J Bustamante, R Tarleton Memorias do Instituto Oswaldo Cruz 110, 445-451, 2015 | 37 | 2015 |
Evidence for the role of vacuolar soluble pyrophosphatase and inorganic polyphosphate in Trypanosoma cruzi persistence M Galizzi, JM Bustamante, J Fang, K Miranda, LC Soares Medeiros, ... Molecular microbiology 90 (4), 699-715, 2013 | 34 | 2013 |
Trypanosoma cruzi: chemotherapeutic effects of clomipramine in mice infected with an isolate obtained from an endemic area HW Rivarola, JM Bustamante, SL Presti, AR Fernández, JE Enders, ... Experimental parasitology 111 (2), 80-86, 2005 | 32 | 2005 |