R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/β-catenin signaling KS Carmon, X Gong, Q Lin, A Thomas, Q Liu Proceedings of the National Academy of Sciences 108 (28), 11452-11457, 2011 | 1003 | 2011 |
LGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/β-catenin signaling KS Carmon, Q Lin, X Gong, A Thomas, Q Liu Molecular and cellular biology 32 (11), 2054-2064, 2012 | 230 | 2012 |
Secreted frizzled-related protein 4 regulates two Wnt7a signaling pathways and inhibits proliferation in endometrial cancer cells KS Carmon, DS Loose Molecular cancer research 6 (6), 1017-1028, 2008 | 188 | 2008 |
LGR6 is a high affinity receptor of R-spondins and potentially functions as a tumor suppressor X Gong, KS Carmon, Q Lin, A Thomas, J Yi, Q Liu PloS one 7 (5), e37137, 2012 | 158 | 2012 |
Inhibition of Rspo-Lgr4 facilitates checkpoint blockade therapy by switching macrophage polarization B Tan, X Shi, J Zhang, J Qin, N Zhang, H Ren, M Qian, S Siwko, ... Cancer research 78 (17), 4929-4942, 2018 | 138 | 2018 |
LGR5-targeted antibody–drug conjugate eradicates gastrointestinal tumors and prevents recurrence X Gong, A Azhdarinia, SC Ghosh, W Xiong, Z An, Q Liu, KS Carmon Molecular cancer therapeutics 15 (7), 1580-1590, 2016 | 110 | 2016 |
RSPO–LGR4 functions via IQGAP1 to potentiate Wnt signaling KS Carmon, X Gong, J Yi, A Thomas, Q Liu Proceedings of the National Academy of Sciences 111 (13), E1221-E1229, 2014 | 106 | 2014 |
Differential activities and mechanisms of the four R-spondins in potentiating Wnt/β-catenin signaling S Park, J Cui, W Yu, L Wu, KS Carmon, QJ Liu Journal of Biological Chemistry 293 (25), 9759-9769, 2018 | 79 | 2018 |
LGR5 receptor promotes cell–cell adhesion in stem cells and colon cancer cells via the IQGAP1–Rac1 pathway KS Carmon, X Gong, J Yi, L Wu, A Thomas, CM Moore, I Masuho, ... Journal of Biological Chemistry 292 (36), 14989-15001, 2017 | 75 | 2017 |
Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness X Gong, J Yi, KS Carmon, CA Crumbley, W Xiong, A Thomas, X Fan, ... Oncogene 34 (36), 4692-4701, 2015 | 65 | 2015 |
Electrochemical impedance biosensor for glucose detection utilizing a periplasmic E. coli receptor protein J Wang, KS Carmon, LA Luck, II Suni Electrochemical and Solid-State Letters 8 (8), H61, 2005 | 64 | 2005 |
A Piezoelectric Quartz Crystal Biosensor: The Use of Two Single Cysteine Mutants of the Periplasmic Escherichia coli Glucose/Galactose Receptor as Target … KS Carmon, RE Baltus, LA Luck Biochemistry 43 (44), 14249-14256, 2004 | 59 | 2004 |
The most common RNF43 mutant G659Vfs* 41 is fully functional in inhibiting Wnt signaling and unlikely to play a role in tumorigenesis J Tu, S Park, W Yu, S Zhang, L Wu, K Carmon, QJ Liu Scientific reports 9 (1), 18557, 2019 | 55 | 2019 |
Application of Immuno-PET in antibody–drug conjugate development KS Carmon, A Azhdarinia Molecular imaging 17, 1536012118801223, 2018 | 55 | 2018 |
Development of a bioassay for detection of Wnt-binding affinities for individual frizzled receptors KS Carmon, DS Loose Analytical biochemistry 401 (2), 288-294, 2010 | 53 | 2010 |
A biosensor for estrogenic substances using the quartz crystal microbalance KS Carmon, RE Baltus, LA Luck Analytical Biochemistry 345 (2), 277-283, 2005 | 44 | 2005 |
Wnt7a interaction with Fzd5 and detection of signaling activation using a split eGFP KS Carmon, DS Loose Biochemical and biophysical research communications 368 (2), 285-291, 2008 | 37 | 2008 |
Quartz crystal microbalance (QCM) with immobilized protein receptors: Comparison of response to ligand binding for direct protein immobilization and protein attachment via … RE Baltus, KS Carmon, LA Luck Langmuir 23 (7), 3880-3885, 2007 | 37 | 2007 |
GPR56 drives colorectal tumor growth and promotes drug resistance through upregulation of MDR1 expression via a RhoA-mediated mechanism S Zhang, T Chatterjee, C Godoy, L Wu, QJ Liu, KS Carmon Molecular Cancer Research 17 (11), 2196-2207, 2019 | 34 | 2019 |
Chromatin state dynamics confers specific therapeutic strategies in enhancer subtypes of colorectal cancer E Orouji, AT Raman, AK Singh, A Sorokin, E Arslan, AK Ghosh, J Schulz, ... Gut 71 (5), 938-949, 2022 | 32 | 2022 |