| Decorin protein core inhibits in vivo cancer growth and metabolism by hindering epidermal growth factor receptor function and triggering apoptosis via caspase-3 activation DG Seidler, S Goldoni, C Agnew, C Cardi, ML Thakur, RT Owens, ... Journal of Biological Chemistry 281 (36), 26408-26418, 2006 | 222 | 2006 |
| A soluble ectodomain of LRIG1 inhibits cancer cell growth by attenuating basal and ligand-dependent EGFR activity S Goldoni, RA Iozzo, P Kay, S Campbell, A McQuillan, C Agnew, JX Zhu, ... Oncogene 26 (3), 368-381, 2007 | 125 | 2007 |
| The Moraxella adhesin UspA1 binds to its human CEACAM1 receptor by a deformable trimeric coiled‐coil R Conners, DJ Hill, E Borodina, C Agnew, SJ Daniell, NM Burton, ... The EMBO journal 27 (12), 1779-1789, 2008 | 100 | 2008 |
| EGF and NRG induce phosphorylation of HER3/ERBB3 by EGFR using distinct oligomeric mechanisms B Van Lengerich, C Agnew, EM Puchner, B Huang, N Jura Proceedings of the National Academy of Sciences 114 (14), E2836-E2845, 2017 | 77 | 2017 |
| Tetraspanins CD81 and CD82 facilitate α4β1-mediated adhesion of human erythroblasts to vascular cell adhesion molecule-1 FA Spring, RE Griffiths, TJ Mankelow, C Agnew, SF Parsons, JA Chasis, ... PloS one 8 (5), e62654, 2013 | 39 | 2013 |
| Functional role of PGAM5 multimeric assemblies and their polymerization into filaments K Ruiz, TM Thaker, C Agnew, L Miller-Vedam, R Trenker, C Herrera, ... Nature communications 10 (1), 531, 2019 | 38 | 2019 |
| Correlation of in situ mechanosensitive responses of the Moraxella catarrhalis adhesin UspA1 with fibronectin and receptor CEACAM1 binding C Agnew, E Borodina, NR Zaccai, R Conners, NM Burton, JA Vicary, ... Proceedings of the National Academy of Sciences 108 (37), 15174-15178, 2011 | 36 | 2011 |
| Accessibility, Reactivity, and Selectivity of Side Chains within a Channel of de Novo Peptide Assembly AJ Burton, F Thomas, C Agnew, KL Hudson, SE Halford, RL Brady, ... Journal of the American Chemical Society 135 (34), 12524-12527, 2013 | 34 | 2013 |
| The crystal structure of the protein kinase HIPK2 reveals a unique architecture of its CMGC-insert region C Agnew, L Liu, S Liu, W Xu, L You, W Yeung, N Kannan, D Jablons, ... Journal of Biological Chemistry 294 (37), 13545-13559, 2019 | 27 | 2019 |
| Structural basis for ALK2/BMPR2 receptor complex signaling through kinase domain oligomerization C Agnew, P Ayaz, R Kashima, HS Loving, P Ghatpande, JE Kung, ... Nature communications 12 (1), 4950, 2021 | 21 | 2021 |
| Structural basis of the mispairing of an artificially expanded genetic information system LF Reichenbach, AA Sobri, NR Zaccai, C Agnew, N Burton, LP Eperon, ... Chem 1 (6), 946-958, 2016 | 18 | 2016 |
| Targetable HER3 functions driving tumorigenic signaling in HER2-amplified cancers MR Campbell, A Ruiz-Saenz, E Peterson, C Agnew, P Ayaz, S Garfinkle, ... Cell reports 38 (5), 2022 | 10 | 2022 |
| An enlarged, adaptable active site in CYP164 family P450 enzymes, the sole P450 in Mycobacterium leprae CRJ Agnew, AGS Warrilow, NM Burton, DC Lamb, SL Kelly, RL Brady Antimicrobial agents and chemotherapy 56 (1), 391-402, 2012 | 9 | 2012 |
| CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids M Lo, A Sharir, MD Paul, H Torosyan, C Agnew, A Li, C Neben, ... Nature communications 13 (1), 2407, 2022 | 5 | 2022 |
| Decorin protein core inhibits in vivo cancer growth and metabolism by hindering EGF receptor function and triggering apoptosis via caspase-3 activation DG Seidler, S Goldoni, C Agnew, C Cardi, ML Thakur, RT Owens, ... J Biol Chem 281 (36), 26408-26418, 2006 | 4 | 2006 |
| Switching on BTK—One Domain at a Time C Agnew, N Jura Structure 25 (10), 1469-1470, 2017 | 2 | 2017 |
| Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of β-Glucocerebrosidase N Palmer, C Agnew, C Benn, WJ Buffham, JN Castro, G Chessari, M Clark, ... Journal of Medicinal Chemistry, 2024 | | 2024 |
| Polymerization of the mitochondrial phosphatase PGAM5 underlies its biological activity. K Ruiz, TM Thaker, L Miller-Vedam, C Agnew, A Frost, N Jura MOLECULAR BIOLOGY OF THE CELL 28, 2017 | | 2017 |
| Multi-Functional Receptor Binding Activity of the Moraxella Catarrhalis Adhesin UspA1 NR Zaccai, C Agnew, E Borodina, R Conners, N Burton, DK Cole, ... Biophysical Journal 100 (3), 54a, 2011 | | 2011 |
| Decorin core inhibits in vivo cancer growth and metabolism DG Seidler, S Goldoni, C Agnew, C Cardi, ML Thakur, RT Owens, ... Matrix Biology 25, S41, 2006 | | 2006 |
