Mitogen-activated protein kinases in innate immunity JSC Arthur, SC Ley Nature Reviews Immunology 13 (9), 679-692, 2013 | 1770 | 2013 |
Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor PW Janes, SC Ley, AI Magee The Journal of cell biology 147 (2), 447-461, 1999 | 1005 | 1999 |
Functions of NF-κB1 and NF-κB2 in immune cell biology S Beinke, SC Ley Biochemical Journal 382 (2), 393-409, 2004 | 848 | 2004 |
CD40 regulates the processing of NF‐κB2 p100 to p52 HJ Coope, PGP Atkinson, B Huhse, M Belich, J Janzen, MJ Holman, ... The EMBO journal, 2002 | 619 | 2002 |
The role of lipid rafts in T cell antigen receptor (TCR) signalling PW Janes, SC Ley, AI Magee, PS Kabouridis Seminars in immunology 12 (1), 23-34, 2000 | 580 | 2000 |
S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes PS Kabouridis, AI Magee, SC Ley The EMBO journal 16 (16), 4983-4998, 1997 | 454 | 1997 |
Cholesterol depletion disrupts lipid rafts and modulates the activity of multiple signaling pathways in T lymphocytes PS Kabouridis, J Janzen, AL Magee, SC Ley European journal of immunology 30 (3), 954-963, 2000 | 444 | 2000 |
New insights into NF-κB regulation and function SC Sun, SC Ley Trends in immunology 29 (10), 469-478, 2008 | 419 | 2008 |
Activation of MEK‐1 and SEK‐1 by Tpl‐2 proto‐oncoprotein, a novel MAP kinase kinase kinase. A Salmeron, TB Ahmad, GW Carlile, D Pappin, RP Narsimhan, SC Ley The EMBO journal 15 (4), 817-826, 1996 | 401 | 1996 |
Isoforms of 14‐3‐3 protein can form homo‐and heterodimers in vivo and in vitro: implications for function as adapter proteins DH Jones, S Ley, A Aitken FEBS letters 368 (1), 55-58, 1995 | 345 | 1995 |
Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH) ME Cockman, DE Lancaster, IP Stolze, KS Hewitson, MA McDonough, ... Proceedings of the National Academy of Sciences 103 (40), 14767-14772, 2006 | 327 | 2006 |
TPL-2 kinase regulates the proteolysis of the NF-κB-inhibitory protein NF-κB1 p105 MP Belich, A Salmerón, LH Johnston, SC Ley Nature 397 (6717), 363-368, 1999 | 276 | 1999 |
Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif M Koegl, P Zlatkine, SC Ley, SA Courtneidge, AI Magee Biochemical Journal 303 (3), 749-753, 1994 | 268 | 1994 |
Lipopolysaccharide activation of the TPL-2/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase cascade is regulated by IκB kinase-induced proteolysis of … S Beinke, MJ Robinson, M Hugunin, SC Ley Molecular and cellular biology, 2004 | 264 | 2004 |
Expression, biological activities and mechanisms of action of A20 (TNFAIP3) L Verstrepen, K Verhelst, G van Loo, I Carpentier, SC Ley, R Beyaert Biochemical pharmacology 80 (12), 2009-2020, 2010 | 243 | 2010 |
Immortalized B lymphocytes produce B-cell growth factor J Gordon, SC Ley, MD Melamed, LS English, NC Hughes-Jones Nature 310 (5973), 145-147, 1984 | 242 | 1984 |
Distinct intracellular localization of Lck and Fyn protein tyrosine kinases in human T lymphocytes. SC Ley, M Marsh, CR Bebbington, K Proudfoot, P Jordan The Journal of cell biology 125 (3), 639-649, 1994 | 223 | 1994 |
TPL-2 negatively regulates interferon-β production in macrophages and myeloid dendritic cells F Kaiser, D Cook, S Papoutsopoulou, R Rajsbaum, X Wu, HT Yang, ... Journal of Experimental Medicine 206 (9), 1863-1871, 2009 | 222 | 2009 |
Regulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinase T Gantke, S Sriskantharajah, SC Ley Cell research 21 (1), 131-145, 2011 | 188 | 2011 |
βTrCP-mediated proteolysis of NF-κB1 p105 requires phosphorylation of p105 serines 927 and 932 V Lang, J Janzen, GZ Fischer, Y Soneji, S Beinke, A Salmeron, H Allen, ... Molecular and cellular biology 23 (1), 402-413, 2003 | 184 | 2003 |