Glioma-initiating cell elimination by metformin activation of FOXO3 via AMPK A Sato, J Sunayama, M Okada, E Watanabe, S Seino, K Shibuya, ... Stem cells translational medicine 1 (11), 811-824, 2012 | 212 | 2012 |
Targeting the facilitative glucose transporter GLUT1 inhibits the self-renewal and tumor-initiating capacity of cancer stem cells K Shibuya, M Okada, S Suzuki, M Seino, S Seino, H Takeda, C Kitanaka Oncotarget 6 (2), 651, 2015 | 191 | 2015 |
Pivotal role for ROS activation of p38 MAPK in the control of differentiation and tumor-initiating capacity of glioma-initiating cells A Sato, M Okada, K Shibuya, E Watanabe, S Seino, Y Narita, S Shibui, ... Stem cell research 12 (1), 119-131, 2014 | 175 | 2014 |
Gambogic amide, a selective agonist for TrkA receptor that possesses robust neurotrophic activity, prevents neuronal cell death SW Jang, M Okada, I Sayeed, G Xiao, D Stein, P Jin, K Ye Proceedings of the National Academy of Sciences 104 (41), 16329-16334, 2007 | 160 | 2007 |
Akt phosphorylation and nuclear phosphoinositide association mediate mRNA export and cell proliferation activities by ALY M Okada, SW Jang, K Ye Proceedings of the National Academy of Sciences 105 (25), 8649-8654, 2008 | 152 | 2008 |
Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B X Tang, SW Jang, M Okada, CB Chan, Y Feng, Y Liu, SW Luo, Y Hong, ... Nature Cell Biology 10 (6), 698-706, 2008 | 132 | 2008 |
Targeting JNK for therapeutic depletion of stem-like glioblastoma cells K Matsuda, A Sato, M Okada, K Shibuya, S Seino, K Suzuki, E Watanabe, ... Scientific reports 2 (1), 516, 2012 | 110 | 2012 |
JNK suppression of chemotherapeutic agents-induced ROS confers chemoresistance on pancreatic cancer stem cells S Suzuki, M Okada, K Shibuya, M Seino, A Sato, H Takeda, S Seino, ... Oncotarget 6 (1), 458, 2015 | 105 | 2015 |
Resveratrol promotes proteasome-dependent degradation of Nanog via p53 activation and induces differentiation of glioma stem cells A Sato, M Okada, K Shibuya, E Watanabe, S Seino, K Suzuki, Y Narita, ... Stem cell research 11 (1), 601-610, 2013 | 94 | 2013 |
Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressor Z Liu, SM Oh, M Okada, X Liu, D Cheng, J Peng, DJ Brat, S Sun, W Zhou, ... Molecular Biology of the Cell 20 (3), 757-768, 2009 | 82 | 2009 |
Targeting the K-Ras-JNK axis eliminates cancer stem-like cells and prevents pancreatic tumor formation M Okada, K Shibuya, A Sato, S Seino, S Suzuki, M Seino, C Kitanaka Oncotarget 5 (13), 5100, 2014 | 75 | 2014 |
JNK contributes to temozolomide resistance of stem-like glioblastoma cells via regulation of MGMT expression M Okada, A Sato, K Shibuya, E Watanabe, S Seino, S Suzuki, M Seino, ... International journal of oncology 44 (2), 591-599, 2014 | 74 | 2014 |
GSKJ4, a selective jumonji H3K27 demethylase inhibitor, effectively targets ovarian cancer stem cells H Sakaki, M Okada, K Kuramoto, H Takeda, H Watarai, S Suzuki, S Seino, ... Anticancer Research 35 (12), 6607-6614, 2015 | 69 | 2015 |
Ebp1 association with nucleophosmin/B23 is essential for regulating cell proliferation and suppressing apoptosis M Okada, SW Jang, K Ye Journal of Biological Chemistry 282 (50), 36744-36754, 2007 | 66 | 2007 |
Differential contribution of ROS to resveratrol-induced cell death and loss of self-renewal capacity of ovarian cancer stem cells M Seino, M Okada, K Shibuya, S Seino, S Suzuki, H Takeda, T Ohta, ... Anticancer Research 35 (1), 85-96, 2015 | 65 | 2015 |
JNK signaling in the control of the tumor-initiating capacity associated with cancer stem cells C Kitanaka, A Sato, M Okada Genes & cancer 4 (9-10), 388-396, 2013 | 56 | 2013 |
Ebp1 sumoylation, regulated by TLS/FUS E3 ligase, is required for its anti-proliferative activity SM Oh, Z Liu, M Okada, SW Jang, X Liu, CB Chan, H Luo, K Ye Oncogene 29 (7), 1017-1030, 2010 | 56 | 2010 |
Nuclear phosphoinositide signaling regulates messenger RNA export M Okada, K Ye RNA biology 6 (1), 12-16, 2009 | 56 | 2009 |
Aripiprazole, an antipsychotic and partial dopamine agonist, inhibits cancer stem cells and reverses chemoresistance S Suzuki, M Okada, K Kuramoto, H Takeda, H Sakaki, H Watarai, ... Anticancer research 36 (10), 5153-5161, 2016 | 55 | 2016 |
The novel JNK inhibitor AS602801 inhibits cancer stem cells in vitro and in vivo M Okada, K Kuramoto, H Takeda, H Watarai, H Sakaki, S Seino, M Seino, ... Oncotarget 7 (19), 27021, 2016 | 55 | 2016 |