Immunomodulatory effects of hydroxychloroquine and chloroquine in viral infections and their potential application in retinal gene therapy LC Chandler, IH Yusuf, ME McClements, AR Barnard, RE MacLaren, ... International journal of molecular sciences 21 (14), 4972, 2020 | 40 | 2020 |
DHX15 regulates CMTR1-dependent gene expression and cell proliferation F Inesta-Vaquera, VK Chaugule, A Galloway, L Chandler, ... Life science alliance 1 (3), 2018 | 37 | 2018 |
Enhancement of adeno-associated virus-mediated gene therapy using hydroxychloroquine in murine and human tissues LC Chandler, AR Barnard, SL Caddy, MI Patrício, ME McClements, H Fu, ... Molecular Therapy Methods & Clinical Development 14, 77-89, 2019 | 35 | 2019 |
Characterizing the cellular immune response to subretinal AAV gene therapy in the murine retina LC Chandler, ME McClements, IH Yusuf, CMF de la Camara, ... Molecular Therapy-Methods & Clinical Development 22, 52-65, 2021 | 19 | 2021 |
Vector shedding and immunology measures in a choroideremia gene therapy trial AR Barnard, A Rudenko, M In, LC Chandler, K Xue, RE MacLaren Investigative Ophthalmology & Visual Science 60 (9), 2919-2919, 2019 | 1 | 2019 |
Gene therapy-associated retinal inflammation may arise from AAV transduction of resident microglia M John, J Quinn, L Chandler, RE MacLaren, K Xue Investigative Ophthalmology & Visual Science 64 (8), 772-772, 2023 | | 2023 |
Enhancement of Adeno-Associated Virus-Mediated Gene Therapy Using Hydroxychloroquine in Murine and Human Tissues LC Chandler, AR Barnard, SL Caddy, MI Patrício, ME McClements, H Fu, ... Molecular Therapy Methods & Clinical Development 28, 300, 2023 | | 2023 |
Immunological responses to retinal gene therapy L Chandler University of Oxford, 2021 | | 2021 |
Cell-mediated inflammatory response to AAV gene therapy in the retina LC Chandler, IH Yusuf, H Ferry, ME McClements, RE MacLaren, K Xue Molecular Therapy 28 (4), 2020 | | 2020 |
Photoreceptor-specific AAV gene replacement enhanced by the adjunctive use of hydroxychloroquine in vivo LC Chandler, ME McClements, AR Barnard, M In, RE MacLaren, K Xue Investigative Ophthalmology & Visual Science 60 (9), 3391-3391, 2019 | | 2019 |
Hydroxychloroquine enhances the efficacy of retinal gene therapy LC Chandler, AR Barnard, K Xue, RE MacLaren Investigative Ophthalmology & Visual Science 59 (9), 6005-6005, 2018 | | 2018 |
Enhancement of AAV Transduction Using Anti-Malarial Drugs, Hydroxychloroquine and Chloroquine K Xue, LC Chandler, AR Barnard, SL Caddy, MI Patricio, H Fu, C Rada, ... MOLECULAR THERAPY 26 (5), 318-318, 2018 | | 2018 |
Assessment of the relationship between CHM gene expression and rate of disease progression in choroideremia M In, K Xue, LC Chandler, AR Barnard, JK Jolly, T Edwards, ... Investigative Ophthalmology & Visual Science 58 (8), 4528-4528, 2017 | | 2017 |
Investigation of intracellular innate immune responses to AAV gene therapy in the retina. LC Chandler, H Fu, S Caddy, AR Barnard, M In, L James, C Rada, ... Investigative Ophthalmology & Visual Science 58 (8), 4491-4491, 2017 | | 2017 |
INVESTIGATION OF THE RELATIONSHIP BETWEEN LEVELS OF CHM GENE EXPRESSION AND RATE OF DISEASE PROGRESSION IN CHOROIDEREMIA M Patricio, K Xue, LC Chandler, AR Barnard, JK Jolly, TL Edwards, ... EUROPEAN JOURNAL OF OPHTHALMOLOGY 27 (2), E86-E86, 2017 | | 2017 |
Enhancement of Adeno-Associated Virus-Mediated Gene Therapy Using Hydroxychloroquine in Murine and Human Tissues LC Chandler, AR Barnard, SL Caddy, MI Patrício, ME McClements, H Fu, ... | | |