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Laurel C Chandler
Laurel C Chandler
Harvard Medical School
在 hms.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Immunomodulatory effects of hydroxychloroquine and chloroquine in viral infections and their potential application in retinal gene therapy
LC Chandler, IH Yusuf, ME McClements, AR Barnard, RE MacLaren, ...
International journal of molecular sciences 21 (14), 4972, 2020
402020
DHX15 regulates CMTR1-dependent gene expression and cell proliferation
F Inesta-Vaquera, VK Chaugule, A Galloway, L Chandler, ...
Life science alliance 1 (3), 2018
372018
Enhancement of adeno-associated virus-mediated gene therapy using hydroxychloroquine in murine and human tissues
LC Chandler, AR Barnard, SL Caddy, MI Patrício, ME McClements, H Fu, ...
Molecular Therapy Methods & Clinical Development 14, 77-89, 2019
352019
Characterizing the cellular immune response to subretinal AAV gene therapy in the murine retina
LC Chandler, ME McClements, IH Yusuf, CMF de la Camara, ...
Molecular Therapy-Methods & Clinical Development 22, 52-65, 2021
192021
Vector shedding and immunology measures in a choroideremia gene therapy trial
AR Barnard, A Rudenko, M In, LC Chandler, K Xue, RE MacLaren
Investigative Ophthalmology & Visual Science 60 (9), 2919-2919, 2019
12019
Gene therapy-associated retinal inflammation may arise from AAV transduction of resident microglia
M John, J Quinn, L Chandler, RE MacLaren, K Xue
Investigative Ophthalmology & Visual Science 64 (8), 772-772, 2023
2023
Enhancement of Adeno-Associated Virus-Mediated Gene Therapy Using Hydroxychloroquine in Murine and Human Tissues
LC Chandler, AR Barnard, SL Caddy, MI Patrício, ME McClements, H Fu, ...
Molecular Therapy Methods & Clinical Development 28, 300, 2023
2023
Immunological responses to retinal gene therapy
L Chandler
University of Oxford, 2021
2021
Cell-mediated inflammatory response to AAV gene therapy in the retina
LC Chandler, IH Yusuf, H Ferry, ME McClements, RE MacLaren, K Xue
Molecular Therapy 28 (4), 2020
2020
Photoreceptor-specific AAV gene replacement enhanced by the adjunctive use of hydroxychloroquine in vivo
LC Chandler, ME McClements, AR Barnard, M In, RE MacLaren, K Xue
Investigative Ophthalmology & Visual Science 60 (9), 3391-3391, 2019
2019
Hydroxychloroquine enhances the efficacy of retinal gene therapy
LC Chandler, AR Barnard, K Xue, RE MacLaren
Investigative Ophthalmology & Visual Science 59 (9), 6005-6005, 2018
2018
Enhancement of AAV Transduction Using Anti-Malarial Drugs, Hydroxychloroquine and Chloroquine
K Xue, LC Chandler, AR Barnard, SL Caddy, MI Patricio, H Fu, C Rada, ...
MOLECULAR THERAPY 26 (5), 318-318, 2018
2018
Assessment of the relationship between CHM gene expression and rate of disease progression in choroideremia
M In, K Xue, LC Chandler, AR Barnard, JK Jolly, T Edwards, ...
Investigative Ophthalmology & Visual Science 58 (8), 4528-4528, 2017
2017
Investigation of intracellular innate immune responses to AAV gene therapy in the retina.
LC Chandler, H Fu, S Caddy, AR Barnard, M In, L James, C Rada, ...
Investigative Ophthalmology & Visual Science 58 (8), 4491-4491, 2017
2017
INVESTIGATION OF THE RELATIONSHIP BETWEEN LEVELS OF CHM GENE EXPRESSION AND RATE OF DISEASE PROGRESSION IN CHOROIDEREMIA
M Patricio, K Xue, LC Chandler, AR Barnard, JK Jolly, TL Edwards, ...
EUROPEAN JOURNAL OF OPHTHALMOLOGY 27 (2), E86-E86, 2017
2017
Enhancement of Adeno-Associated Virus-Mediated Gene Therapy Using Hydroxychloroquine in Murine and Human Tissues
LC Chandler, AR Barnard, SL Caddy, MI Patrício, ME McClements, H Fu, ...
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