After nerve injury, lineage tracing shows that myelin and Remak Schwann cells elongate extensively and branch to form repair Schwann cells, which shorten radically on remyelination JA Gomez-Sanchez, KS Pilch, M van der Lans, SV Fazal, C Benito, ... Journal of Neuroscience 37 (37), 9086-9099, 2017 | 237 | 2017 |
Changes in the coding and non-coding transcriptome and DNA methylome that define the Schwann cell repair phenotype after nerve injury PJ Arthur-Farraj, CC Morgan, M Adamowicz, JA Gomez-Sanchez, ... Cell reports 20 (11), 2719-2734, 2017 | 174 | 2017 |
Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun LJ Wagstaff, JA Gomez-Sanchez, SV Fazal, GW Otto, AM Kilpatrick, ... Elife 10, e62232, 2021 | 86 | 2021 |
Graded elevation of c-jun in Schwann cells in vivo: gene dosage determines effects on development, remyelination, tumorigenesis, and hypomyelination SV Fazal, JA Gomez-Sanchez, LJ Wagstaff, N Musner, G Otto, M Janz, ... Journal of Neuroscience 37 (50), 12297-12313, 2017 | 83 | 2017 |
The sleep and circadian problems of Huntington’s disease: when, why and their importance Z Voysey, SV Fazal, AS Lazar, RA Barker Journal of Neurology, 1-9, 2020 | 30 | 2020 |
Hyperosmotic stress induces cell-dependent aggregation of α-synuclein AMC Fragniere, SRW Stott, SV Fazal, M Andreasen, K Scott, RA Barker Scientific reports 9 (1), 2288, 2019 | 13 | 2019 |
Hyperosmotic stress induces cell-dependent aggregation of α-synuclein RA Barker, A Fragniere, S Stott, SV Fazal, M Andreasen, K Scott Nature Publishing Group, 2019 | 13* | 2019 |
Levels of Schwann cell c-Jun control nerve development and response to injury SV Fazal UCL (University College London), 2017 | 1 | 2017 |
schwann cells in the proximal stump of injured nerves activate c-jun to control the intrinsic growth state and regeneration potential of Drg sensory neurons: t14-10b S Fazal, K Bartus, M Iberl, D Wilton, EJ Bradbury, R Mirsky, KR Jessen Glia 63, E432-E433, 2015 | 1 | 2015 |
The well documented failures of nerve repair seen during aging and chronic denervation involve reduced Schwann cell c-Jun, and are rescued by restoring c-Jun levels. KR Jessen, LJ Wagstaff, JA Gomez-Sanchez, SV Fazal, P Arthur-Farraj, ... GLIA 69, E88-E89, 2021 | | 2021 |
Do injured axons signal to Schwann cells prior to axon degeneration? P Arthur-Farraj, J Gomez-Sanchez, S Fazal, C Mutschler, B House, ... GLIA 69, E76-E77, 2021 | | 2021 |
Characterising the Schwann cell early injury response in mouse and zebrafish C Mutschler, J Gomez-Sanchez, D Chairugi, S Fazal, A Loreto, H Cabedo, ... GLIA 69, E515-E516, 2021 | | 2021 |
Over-expression of Schwann cell c-Jun in vivo: effect on myelination and re-myelination S Fazal, JA Gomez-Sanchez, R Mirsky, KR Jessen 13th European Meeting on Glial Cells in Health and Disease, 2017 | | 2017 |
Epigenetic Factors That Mark The Schwann Cell Regenerative Phenotype During Nerve Injury P Arthur-Farraj, CC Morgan, M Adamowicz-Brice, J Gomez-Sanchez, ... Journal of the Peripheral Nervous System 20 (2), 97, 2015 | | 2015 |