TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity A Caputo, E Caci, L Ferrera, N Pedemonte, C Barsanti, E Sondo, U Pfeffer, ... Science 322 (5901), 590-594, 2008 | 1434 | 2008 |
Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin–induced intestinal fluid secretion T Ma, JR Thiagarajah, H Yang, ND Sonawane, C Folli, LJV Galietta, ... The Journal of clinical investigation 110 (11), 1651-1658, 2002 | 822 | 2002 |
Small-molecule correctors of defective ΔF508-CFTR cellular processing identified by high-throughput screening N Pedemonte, GL Lukacs, K Du, E Caci, O Zegarra-Moran, LJV Galietta, ... The Journal of clinical investigation 115 (9), 2564-2571, 2005 | 673 | 2005 |
Chloride channels as drug targets AS Verkman, LJV Galietta Nature reviews Drug discovery 8 (2), 153-171, 2009 | 576 | 2009 |
Structure and function of TMEM16 proteins (anoctamins) N Pedemonte, LJV Galietta Physiological reviews 94 (2), 419-459, 2014 | 549 | 2014 |
Green fluorescent protein-based halide indicators with improved chloride and iodide affinities LJV Galietta, PM Haggie, AS Verkman FEBS letters 499 (3), 220-224, 2001 | 445 | 2001 |
Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure–activity analysis, and in vivo efficacy C Muanprasat, ND Sonawane, D Salinas, A Taddei, LJV Galietta, ... The Journal of general physiology 124 (2), 125-137, 2004 | 312 | 2004 |
Cell-based assay for high-throughput quantitative screening of CFTR chloride transport agonists LVJ Galietta, S Jayaraman, AS Verkman American Journal of Physiology-Cell Physiology 281 (5), C1734-C1742, 2001 | 279 | 2001 |
Nanomolar affinity small molecule correctors of defective ΔF508-CFTR chloride channel gating H Yang, AA Shelat, RK Guy, VS Gopinath, T Ma, K Du, GL Lukacs, ... Journal of Biological Chemistry 278 (37), 35079-35085, 2003 | 265 | 2003 |
High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening T Ma, L Vetrivel, H Yang, N Pedemonte, O Zegarra-Moran, LJV Galietta, ... Journal of Biological Chemistry 277 (40), 37235-37241, 2002 | 252 | 2002 |
Regulation of TMEM16A chloride channel properties by alternative splicing L Ferrera, A Caputo, I Ubby, E Bussani, O Zegarra-Moran, R Ravazzolo, ... Journal of Biological Chemistry 284 (48), 33360-33368, 2009 | 250 | 2009 |
Novel CFTR Chloride Channel Activators Identified by Screening of Combinatorial Libraries Based on Flavone and Benzoquinolizinium Lead Compounds* 210 LJV Galietta, MF Springsteel, M Eda, EJ Niedzinski, MJ Haddadin, ... Journal of Biological Chemistry 276 (23), 19723-19728, 2001 | 247 | 2001 |
Phenylglycine and sulfonamide correctors of defective ΔF508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating N Pedemonte, ND Sonawane, A Taddei, J Hu, O Zegarra-Moran, YF Suen, ... Molecular pharmacology 67 (5), 1797-1807, 2005 | 191 | 2005 |
Contribution of CFTR to apical-basolateral fluid transport in cultured human alveolar epithelial type II cells X Fang, Y Song, J Hirsch, LJV Galietta, N Pedemonte, RL Zemans, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 290 (2 …, 2006 | 184 | 2006 |
Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia P Scudieri, E Caci, S Bruno, L Ferrera, M Schiavon, E Sondo, V Tomati, ... The Journal of physiology 590 (23), 6141-6155, 2012 | 182 | 2012 |
Targeting ion channels in cystic fibrosis MA Mall, LJV Galietta Journal of Cystic Fibrosis 14 (5), 561-570, 2015 | 178 | 2015 |
IL-4 is a potent modulator of ion transport in the human bronchial epithelium in vitro LJV Galietta, P Pagesy, C Folli, E Caci, L Romio, B Costes, E Nicolis, ... The Journal of Immunology 168 (2), 839-845, 2002 | 174 | 2002 |
Thiocyanate transport in resting and IL-4-stimulated human bronchial epithelial cells: role of pendrin and anion channels N Pedemonte, E Caci, E Sondo, A Caputo, K Rhoden, U Pfeffer, ... The Journal of Immunology 178 (8), 5144-5153, 2007 | 170 | 2007 |
Correction of delF508-CFTR activity with benzo (c) quinolizinium compounds through facilitation of its processing in cystic fibrosis airway cells RL Dormer, R Dérand, CM McNeilly, Y Mettey, L Bulteau-Pignoux, ... Journal of Cell Science 114 (22), 4073-4081, 2001 | 146 | 2001 |
TMEM16A Protein: A New Identity for Ca2+-Dependent Cl− Channels L Ferrera, A Caputo, LJV Galietta Physiology 25 (6), 357-363, 2010 | 145 | 2010 |