| Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia S Klossowski, H Miao, K Kempinska, T Wu, T Purohit, EG Kim, ... The Journal of clinical investigation 130 (2), 981-997, 2020 | 174 | 2020 |
| Discovery and optimization of 1, 3, 4-trisubstituted-pyrazolone derivatives as novel, potent, and nonsteroidal farnesoid X receptor (FXR) selective antagonists H Huang, Y Yu, Z Gao, Y Zhang, C Li, X Xu, H Jin, W Yan, R Ma, J Zhu, ... Journal of Medicinal Chemistry 55 (16), 7037-7053, 2012 | 68 | 2012 |
| Covalent inhibition of NSD1 histone methyltransferase H Huang, CA Howard, S Zari, HJ Cho, S Shukla, H Li, J Ndoj, ... Nature chemical biology 16 (12), 1403-1410, 2020 | 60 | 2020 |
| Design and synthesis of small molecule RhoA inhibitors: a new promising therapy for cardiovascular diseases? J Deng, E Feng, S Ma, Y Zhang, X Liu, H Li, H Huang, J Zhu, W Zhu, ... Journal of medicinal chemistry 54 (13), 4508-4522, 2011 | 56 | 2011 |
| Design and synthesis of small molecular dual inhibitor of falcipain-2 and dihydrofolate reductase as antimalarial agent H Huang, W Lu, X Li, X Cong, H Ma, X Liu, Y Zhang, P Che, R Ma, H Li, ... Bioorganic & medicinal chemistry letters 22 (2), 958-962, 2012 | 43 | 2012 |
| I−/TBHP catalyzed C sp3–N/C sp2–N bond formation via oxidative coupling with benzophenone imine in water H Huang, W Chen, Y Xu, J Li Green Chemistry 17 (10), 4715-4719, 2015 | 31 | 2015 |
| Design, synthesis, and biological evaluation of novel nonsteroidal farnesoid X receptor (FXR) antagonists: molecular basis of FXR antagonism H Huang, P Si, L Wang, Y Xu, X Xu, J Zhu, H Jiang, W Li, L Chen, J Li ChemMedChem 10 (7), 1184-1199, 2015 | 22 | 2015 |
| Recent advances in non-steroidal FXR antagonists development for therapeutic applications H Huang, Y Xu, J Zhu, J Li Current topics in medicinal chemistry 14 (19), 2175-2187, 2014 | 16 | 2014 |
| Covalent drug discovery using sulfur (VI) fluoride exchange warheads H Huang, LH Jones Expert Opinion on Drug Discovery 18 (7), 725-735, 2023 | 8 | 2023 |
| A highly efficient approach to unnatural amino-acids containing 3-hydroxyoxindole skeleton via a one-pot, three-component procedure H Huang, Y Xu, F Mao, J Zhu, H Jiang, J Li Tetrahedron Letters 56 (4), 586-589, 2015 | 6 | 2015 |
| Covalent Stapling of the Cereblon Sensor Loop Histidine Using Sulfur-Heterocycle Exchange JT Cruite, RP Nowak, KA Donovan, SB Ficarro, H Huang, H Liu, Y Liu, ... ACS Medicinal Chemistry Letters 14 (11), 1576-1581, 2023 | 2 | 2023 |
| NSD family inhibitors and methods of treatment therewith T Cierpicki, J Grembecka, H Huang, S Zari, HJ Cho, M Potopnyk, ... US Patent 11,324,729, 2022 | 1 | 2022 |
| Nsd family inhibitors and methods of treatment therewith T Cierpicki, J Grembecka, H Huang, S Zari, HJ Cho, M Potopnyk, ... US Patent App. 17/729,836, 2023 | | 2023 |
| Targeting NSD family histone methyltransferase activity with irreversible inhibitors C Howard, S Zari, S Li, H Huang, E Kim, SR Park, T Purohit, H Miao, ... Cancer Research 82 (12_Supplement), 3274-3274, 2022 | | 2022 |
