Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats G Hargus, O Cooper, M Deleidi, A Levy, K Lee, E Marlow, A Yow, ... Proceedings of the National Academy of Sciences 107 (36), 15921-15926, 2010 | 575 | 2010 |
Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson’s disease O Cooper, H Seo, S Andrabi, C Guardia-Laguarta, J Graziotto, ... Science translational medicine 4 (141), 141ra90-141ra90, 2012 | 541 | 2012 |
iPSC-derived neurons from GBA1-associated Parkinson’s disease patients show autophagic defects and impaired calcium homeostasis DC Schöndorf, M Aureli, FE McAllister, CJ Hindley, F Mayer, B Schmid, ... Nature communications 5 (1), 4028, 2014 | 512 | 2014 |
Successful function of autologous iPSC-derived dopamine neurons following transplantation in a non-human primate model of Parkinson’s disease PJ Hallett, M Deleidi, A Astradsson, GA Smith, O Cooper, TM Osborn, ... Cell stem cell 16 (3), 269-274, 2015 | 361 | 2015 |
The NAD+ precursor nicotinamide riboside rescues mitochondrial defects and neuronal loss in iPSC and fly models of Parkinson’s disease DC Schöndorf, D Ivanyuk, P Baden, A Sanchez-Martinez, S De Cicco, ... Cell reports 23 (10), 2976-2988, 2018 | 278 | 2018 |
Persistent inflammation alters the function of the endogenous brain stem cell compartment S Pluchino, L Muzio, J Imitola, M Deleidi, C Alfaro-Cervello, G Salani, ... Brain 131 (10), 2564-2578, 2008 | 270 | 2008 |
Immune aging, dysmetabolism, and inflammation in neurological diseases M Deleidi, M Jäggle, G Rubino Frontiers in neuroscience 9, 172, 2015 | 265 | 2015 |
Differentiation of human ES and Parkinson's disease iPS cells into ventral midbrain dopaminergic neurons requires a high activity form of SHH, FGF8a and specific … O Cooper, G Hargus, M Deleidi, A Blak, T Osborn, E Marlow, K Lee, ... Molecular and Cellular Neuroscience 45 (3), 258-266, 2010 | 254 | 2010 |
The role of inflammation in sporadic and familial Parkinson’s disease M Deleidi, T Gasser Cellular and Molecular Life Sciences 70, 4259-4273, 2013 | 192 | 2013 |
Neural stem cells and their use as therapeutic tool in neurological disorders S Pluchino, L Zanotti, M Deleidi, G Martino Brain Research Reviews 48 (2), 211-219, 2005 | 176 | 2005 |
Plasticity of subventricular zone neuroprogenitors in MPTP (1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine) mouse model of Parkinson's disease involves cross talk between … F L'Episcopo, C Tirolo, N Testa, S Caniglia, MC Morale, M Deleidi, ... Journal of Neuroscience 32 (6), 2062-2085, 2012 | 143 | 2012 |
The Toll-like receptor-3 agonist polyinosinic: polycytidylic acid triggers nigrostriatal dopaminergic degeneration M Deleidi, PJ Hallett, JB Koprich, CY Chung, O Isacson Journal of Neuroscience 30 (48), 16091-16101, 2010 | 125 | 2010 |
Genome-scale networks link neurodegenerative disease genes to α-synuclein through specific molecular pathways V Khurana, J Peng, CY Chung, PK Auluck, S Fanning, DF Tardiff, ... Cell systems 4 (2), 157-170. e14, 2017 | 124 | 2017 |
Viral and inflammatory triggers of neurodegenerative diseases M Deleidi, O Isacson Science translational medicine 4 (121), 121ps3-121ps3, 2012 | 97 | 2012 |
Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer’s disease-like pathology in human cerebral organoids MJ Pérez, D Ivanyuk, V Panagiotakopoulou, G Di Napoli, S Kalb, ... Molecular psychiatry 26 (10), 5733-5750, 2021 | 87 | 2021 |
The GBAP1 pseudogene acts as a ceRNA for the glucocerebrosidase gene GBA by sponging miR-22-3p L Straniero, V Rimoldi, M Samarani, S Goldwurm, A Di Fonzo, R Krüger, ... Scientific reports 7 (1), 12702, 2017 | 69 | 2017 |
Development of histocompatible primate‐induced pluripotent stem cells for neural transplantation M Deleidi, G Hargus, P Hallett, T Osborn, O Isacson Stem cells 29 (7), 1052-1063, 2011 | 68 | 2011 |
Interferon-γ signaling synergizes with LRRK2 in neurons and microglia derived from human induced pluripotent stem cells V Panagiotakopoulou, D Ivanyuk, S De Cicco, W Haq, A Arsić, C Yu, ... Nature Communications 11 (1), 5163, 2020 | 62 | 2020 |
Protein clearance mechanisms of alpha-synuclein and amyloid-Beta in lewy body disorders M Deleidi, W Maetzler International Journal of Alzheimer’s Disease 2012, 2012 | 58 | 2012 |
Mitochondrial dysregulation and impaired autophagy in iPSC-derived dopaminergic neurons of multiple system atrophy GM Compagnoni, G Kleiner, M Samarani, M Aureli, G Faustini, A Bellucci, ... Stem Cell Reports 11 (5), 1185-1198, 2018 | 54 | 2018 |