| Sigma-2 Receptor/TMEM97 and PGRMC-1 Increase the Rate of Internalization of LDL by LDL Receptor through the Formation of a Ternary Complex A Riad, C Zeng, CC Weng, H Winters, K Xu, M Makvandi, T Metz, S Carlin, ... Scientific reports 8 (1), 16845, 2018 | 119 | 2018 |
| The sigma-2 receptor/TMEM97, PGRMC1, and LDL receptor complex are responsible for the cellular uptake of Aβ42 and its protein aggregates A Riad, Z Lengyel-Zhand, C Zeng, CC Weng, VMY Lee, JQ Trojanowski, ... Molecular neurobiology 57, 3803-3813, 2020 | 57 | 2020 |
| TMEM97 and PGRMC1 do not mediate sigma-2 ligand-induced cell death C Zeng, CC Weng, ME Schneider Jr, L Puentes, A Riad, K Xu, ... Cell death discovery 5 (1), 58, 2019 | 54 | 2019 |
| Atherosclerosis—do we know enough already to prevent it? CA Narasimhulu, I Fernandez-Ruiz, K Selvarajan, X Jiang, B Sengupta, ... Current Opinion in Pharmacology 27, 92-102, 2016 | 49 | 2016 |
| Inflammatory diseases of the gut M Rohr, CA Narasimhulu, D Sharma, M Doomra, A Riad, S Naser, ... Journal of medicinal food 21 (2), 113-126, 2018 | 39 | 2018 |
| The biological function of sigma-2 receptor/TMEM97 and its utility in PET imaging studies in cancer C Zeng, A Riad, RH Mach Cancers 12 (7), 1877, 2020 | 38 | 2020 |
| Mature VLDL triggers the biogenesis of a distinct vesicle from the trans-Golgi network for its export to the plasma membrane T Hossain, A Riad, S Siddiqi, S Parthasarathy, SA Siddiqi Biochemical Journal 459 (1), 47-58, 2014 | 38 | 2014 |
| PARP-1–Targeted Auger Emitters Display High-LET Cytotoxic Properties In Vitro but Show Limited Therapeutic Utility in Solid Tumor Models of Human Neuroblastoma H Lee, A Riad, P Martorano, A Mansfield, M Samanta, V Batra, RH Mach, ... Journal of Nuclear Medicine 61 (6), 850-856, 2020 | 30 | 2020 |
| Alzheimer's disease—current status and future directions D Bhardwaj, C Mitra, CA Narasimhulu, A Riad, M Doomra, ... Journal of medicinal food 20 (12), 1141-1151, 2017 | 29 | 2017 |
| Proceedings from the fourth international symposium on σ-2 receptors: Role in health and disease NJ Izzo, M Colom-Cadena, AA Riad, J Xu, M Singh, C Abate, MA Cahill, ... eneuro 7 (6), 2020 | 24 | 2020 |
| Parp theranostic auger emitters are cytotoxic in brca mutant ovarian cancer and viable tumors from ovarian cancer patients enable ex-vivo screening of tumor response A Riad, SB Gitto, H Lee, HD Winters, PM Martorano, CJ Hsieh, K Xu, ... Molecules 25 (24), 6029, 2020 | 23 | 2020 |
| Synthesis and evaluation of an AZD2461 [18F] PET probe in non-human primates reveals the PARP-1 inhibitor to be non-blood-brain barrier penetrant SW Reilly, LN Puentes, A Schmitz, CJ Hsieh, CC Weng, C Hou, S Li, ... Bioorganic chemistry 83, 242-249, 2019 | 21 | 2019 |
| Primary prevention of atherosclerosis by pretreatment of low-density lipoprotein receptor knockout mice with sesame oil and its aqueous components C Aluganti Narasimhulu, KY Burge, M Doomra, A Riad, S Parthasarathy Scientific Reports 8 (1), 12270, 2018 | 19 | 2018 |
| Leveraging a Low-Affinity Diazaspiro Orthosteric Fragment to Reduce Dopamine D3 Receptor (D3R) Ligand Promiscuity across Highly Conserved Aminergic G … SW Reilly, AA Riad, CJ Hsieh, K Sahlholm, DA Jacome, S Griffin, M Taylor, ... Journal of Medicinal Chemistry 62 (10), 5132-5147, 2019 | 18 | 2019 |
| Sesame oil and an aqueous extract derived from sesame oil enhance regression of preexisting atherosclerotic lesions in low-density lipoprotein receptor knockout mice CA Narasimhulu, A Riad, S Parthasarathy Journal of medicinal food 21 (7), 641-646, 2018 | 15 | 2018 |
| Protein disulfide isomerase does not act as an unfoldase in the disassembly of cholera toxin P Cherubin, J Guyette, M Taylor, M O’Donnell, L Herndon, H Burress, ... Bioscience Reports 38 (5), BSR20181320, 2018 | 14 | 2018 |
| Screening of σ2 Receptor Ligands and In Vivo Evaluation of 11C-Labeled 6,7-Dimethoxy-2-[4-(4-methoxyphenyl)butan-2-yl]-1,2,3,4-tetrahydroisoquinoline for Potential Use … HY Kim, JY Lee, CJ Hsieh, A Riad, NJ Izzo, SM Catalano, TJA Graham, ... Journal of Medicinal Chemistry 65 (8), 6261-6272, 2022 | 12 | 2022 |
| Pre-clinical investigation of astatine-211-parthanatine for high-risk neuroblastoma M Makvandi, M Samanta, P Martorano, H Lee, SB Gitto, K Patel, D Groff, ... Communications Biology 5 (1), 1260, 2022 | 11 | 2022 |
| Interaction of ligands for pet with the dopamine D3 receptor: In silico and in vitro methods CJ Hsieh, A Riad, JY Lee, K Sahlholm, K Xu, RR Luedtke, RH Mach Biomolecules 11 (4), 529, 2021 | 9 | 2021 |
| Synthesis, binding, and functional properties of tetrahydroisoquinolino-2-alkyl phenones as selective σ2R/TMEM97 ligands XY Xie, YY Li, WH Ma, AF Chen, YT Sun, JY Lee, A Riad, DH Xu, ... European Journal of Medicinal Chemistry 209, 112906, 2021 | 8 | 2021 |
