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Carbonic anhydrase (CA IX) expression, a potential new intrinsic marker of hypoxia: correlations with tumor oxygen measurements and prognosis in locally advanced carcinoma of … JA Loncaster, AL Harris, SE Davidson, JP Logue, RD Hunter, CC Wycoff, ... Cancer research 61 (17), 6394-6399, 2001 | 624 | 2001 |
Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX V Alterio, M Hilvo, A Di Fiore, CT Supuran, P Pan, S Parkkila, A Scaloni, ... Proceedings of the National Academy of Sciences 106 (38), 16233-16238, 2009 | 561 | 2009 |
Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma SK Chia, CC Wykoff, PH Watson, C Han, RD Leek, J Pastorek, KC Gatter, ... Journal of Clinical Oncology 19 (16), 3660-3668, 2001 | 531 | 2001 |
HumanMN/CA9Gene, a novel member of the carbonic anhydrase family: Structure and Exon to protein domain relationships R Opavský, S Pastoreková, V Zelnı́k, A Gibadulinová, EJ Stanbridge, ... Genomics 33 (3), 480-487, 1996 | 492 | 1996 |
Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer A Giatromanolaki, MI Koukourakis, E Sivridis, J Pastorek, CC Wykoff, ... Cancer research 61 (21), 7992-7998, 2001 | 443 | 2001 |
Carbonic anhydrase IX, MN/CA IX: analysis of stomach complementary DNA sequence and expression in human and rat alimentary tracts S Pastorekova, S Parkkila, AK Parkkila, R Opavsky, V Zelnik, J Saarnio, ... GASTROENTEROLOGY-BALTIMORE THEN PHILADELPHIA- 112, 398-408, 1997 | 419 | 1997 |
Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes M Hilvo, L Baranauskiene, AM Salzano, A Scaloni, D Matulis, A Innocenti, ... Journal of Biological Chemistry 283 (41), 27799-27809, 2008 | 371 | 2008 |
Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non–small-cell lung cancer DEB Swinson, JL Jones, D Richardson, C Wykoff, H Turley, J Pastorek, ... Journal of Clinical Oncology 21 (3), 473-482, 2003 | 367 | 2003 |
Carbonic anhydrase inhibitor suppresses invasion of renal cancer cells in vitro S Parkkila, H Rajaniemi, AK Parkkila, J Kivelä, A Waheed, S Pastoreková, ... Proceedings of the National Academy of Sciences 97 (5), 2220-2224, 2000 | 346 | 2000 |
Hypoxia-induced carbonic anhydrase IX as a target for cancer therapy: from biology to clinical use J Pastorek, S Pastorekova Seminars in cancer biology 31, 52-64, 2015 | 335 | 2015 |
Carbonic anhydrase IX, an endogenous hypoxia marker, expression in head and neck squamous cell carcinoma and its relationship to hypoxia, necrosis, and microvessel density NJP Beasley, CC Wykoff, PH Watson, R Leek, H Turley, K Gatter, ... Cancer research 61 (13), 5262-5267, 2001 | 330 | 2001 |
Immunohistochemical study of colorectal tumors for expression of a novel transmembrane carbonic anhydrase, MN/CA IX, with potential value as a marker of cell proliferation J Saarnio, S Parkkila, AK Parkkila, K Haukipuro, S Pastoreková, ... The American journal of pathology 153 (1), 279-285, 1998 | 321 | 1998 |
Carbonic anhydrase IX reduces E-cadherin-mediated adhesion of MDCK cells via interaction with β-catenin E Švastová, N Žilka, M Zat'ovičová, A Gibadulinová, F Čiampor, ... Experimental cell research 290 (2), 332-345, 2003 | 298 | 2003 |
Expression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breast CC Wykoff, N Beasley, PH Watson, L Campo, SK Chia, R English, ... The American journal of pathology 158 (3), 1011-1019, 2001 | 286 | 2001 |
Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides—a new target for the design of antitumor and antiglaucoma drugs? D Vullo, A Innocenti, I Nishimori, J Pastorek, A Scozzafava, S Pastoreková, ... Bioorganic & medicinal chemistry letters 15 (4), 963-969, 2005 | 265 | 2005 |
Hypoxia-regulated carbonic anhydrase-9 (CA9) relates to poor vascularization and resistance of squamous cell head and neck cancer to chemoradiotherapy MI Koukourakis, A Giatromanolaki, E Sivridis, K Simopoulos, J Pastorek, ... Clinical Cancer Research 7 (11), 3399-3403, 2001 | 259 | 2001 |
Hypoxia-regulated carbonic anhydrase IX expression is associated with poor survival in patients with invasive breast cancer SA Hussain, R Ganesan, G Reynolds, L Gross, A Stevens, J Pastorek, ... British journal of cancer 96 (1), 104-109, 2007 | 254 | 2007 |