| Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation AK Buell, C Galvagnion, R Gaspar, E Sparr, M Vendruscolo, TPJ Knowles, ... Proceedings of the National Academy of Sciences 111 (21), 7671-7676, 2014 | 703 | 2014 |
| Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation C Galvagnion, AK Buell, G Meisl, TCT Michaels, M Vendruscolo, ... Nature chemical biology 11 (3), 229-234, 2015 | 665 | 2015 |
| Mutations associated with familial Parkinson’s disease alter the initiation and amplification steps of α-synuclein aggregation P Flagmeier, G Meisl, M Vendruscolo, TPJ Knowles, CM Dobson, ... Proceedings of the National Academy of Sciences 113 (37), 10328-10333, 2016 | 320 | 2016 |
| Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein C Galvagnion, JWP Brown, MM Ouberai, P Flagmeier, M Vendruscolo, ... Proceedings of the National Academy of Sciences 113 (26), 7065-7070, 2016 | 316 | 2016 |
| A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity M Perni, C Galvagnion, A Maltsev, G Meisl, MBD Müller, PK Challa, ... Proceedings of the National Academy of Sciences 114 (6), E1009-E1017, 2017 | 309 | 2017 |
| The role of lipids interacting with α-synuclein in the pathogenesis of Parkinson’s disease C Galvagnion Journal of Parkinson's disease 7 (3), 433-450, 2017 | 252 | 2017 |
| α-Synuclein senses lipid packing defects and induces lateral expansion of lipids leading to membrane remodeling MM Ouberai, J Wang, MJ Swann, C Galvagnion, T Guilliams, CM Dobson, ... Journal of Biological Chemistry 288 (29), 20883-20895, 2013 | 228 | 2013 |
| Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes J Habchi, S Chia, C Galvagnion, TCT Michaels, MMJ Bellaiche, ... Nature chemistry 10 (6), 673-683, 2018 | 223 | 2018 |
| Ostwald’s rule of stages governs structural transitions and morphology of dipeptide supramolecular polymers A Levin, TO Mason, L Adler-Abramovich, AK Buell, G Meisl, C Galvagnion, ... Nature communications 5 (1), 5219, 2014 | 219 | 2014 |
| Direct observation of heterogeneous amyloid fibril growth kinetics via two-color super-resolution microscopy D Pinotsi, AK Buell, C Galvagnion, CM Dobson, GS Kaminski Schierle, ... Nano letters 14 (1), 339-345, 2014 | 201 | 2014 |
| Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson’s disease G Toth, SJ Gardai, W Zago, CW Bertoncini, N Cremades, SL Roy, ... PloS one 9 (2), e87133, 2014 | 161 | 2014 |
| The inverted free energy landscape of an intrinsically disordered peptide by simulations and experiments D Granata, F Baftizadeh, J Habchi, C Galvagnion, A De Simone, ... Scientific reports 5 (1), 15449, 2015 | 146 | 2015 |
| Conformational stability and folding mechanisms of dimeric proteins JAO Rumfeldt, C Galvagnion, KA Vassall, EM Meiering Progress in biophysics and molecular biology 98 (1), 61-84, 2008 | 124 | 2008 |
| Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine M Perni, P Flagmeier, R Limbocker, R Cascella, FA Aprile, C Galvagnion, ... ACS chemical biology 13 (8), 2308-2319, 2018 | 109 | 2018 |
| β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces JWP Brown, AK Buell, TCT Michaels, G Meisl, J Carozza, P Flagmeier, ... Scientific reports 6 (1), 36010, 2016 | 95 | 2016 |
| C-terminal truncation of α-synuclein promotes amyloid fibril amplification at physiological pH IM van der Wateren, TPJ Knowles, AK Buell, CM Dobson, C Galvagnion Chemical science 9 (25), 5506-5516, 2018 | 85 | 2018 |
| An engineered monomer binding-protein for α-synuclein efficiently inhibits the proliferation of amyloid fibrils ED Agerschou, P Flagmeier, T Saridaki, C Galvagnion, D Komnig, L Heid, ... Elife 8, e46112, 2019 | 70 | 2019 |
| Lipid dynamics and phase transition within α-synuclein amyloid fibrils C Galvagnion, D Topgaard, K Makasewicz, AK Buell, S Linse, E Sparr, ... The journal of physical chemistry letters 10 (24), 7872-7877, 2019 | 49 | 2019 |
| Sphingolipid changes in Parkinson L444P GBA mutation fibroblasts promote α-synuclein aggregation C Galvagnion, FR Marlet, S Cerri, AHV Schapira, F Blandini, DA Di Monte Brain 145 (3), 1038-1051, 2022 | 46 | 2022 |
| Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell A Chattopadhyay, CJ O’Connor, F Zhang, C Galvagnion, WRJD Galloway, ... Scientific reports 6 (1), 23732, 2016 | 45 | 2016 |
Alexander K BuellProfessor of Protein Biophysics, Technical University of Denmark, DTU在 dtu.dk 的电子邮件经过验证
