A microRNA component of the p53 tumour suppressor network L He, X He, LP Lim, E De Stanchina, Z Xuan, Y Liang, W Xue, L Zender, ... Nature 447 (7148), 1130-1134, 2007 | 3351 | 2007 |
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas W Xue, L Zender, C Miething, RA Dickins, E Hernando, V Krizhanovsky, ... Nature 445 (7128), 656-660, 2007 | 2860 | 2007 |
Senescence of activated stellate cells limits liver fibrosis V Krizhanovsky, M Yon, RA Dickins, S Hearn, J Simon, C Miething, H Yee, ... Cell 134 (4), 657-667, 2008 | 2128 | 2008 |
A complex secretory program orchestrated by the inflammasome controls paracrine senescence JC Acosta, A Banito, T Wuestefeld, A Georgilis, P Janich, JP Morton, ... Nature cell biology 15 (8), 978-990, 2013 | 1969 | 2013 |
Senescence surveillance of pre-malignant hepatocytes limits liver cancer development Nature 7374 (Nov 9;479), 547-51, 2011 | 1578* | 2011 |
Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach L Zender, MS Spector, W Xue, P Flemming, C Cordon-Cardo, J Silke, ... Cell 125 (7), 1253-1267, 2006 | 1248 | 2006 |
Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence S Glück, B Guey, MF Gulen, K Wolter, TW Kang, NA Schmacke, ... Nature cell biology 19 (9), 1061-1070, 2017 | 910 | 2017 |
NASH limits anti-tumour surveillance in immunotherapy-treated HCC D Pfister, NG Núñez, R Pinyol, O Govaere, M Pinter, M Szydlowska, ... Nature 592 (7854), 450-456, 2021 | 816 | 2021 |
T-helper-1-cell cytokines drive cancer into senescence H Braumüller, T Wieder, E Brenner, S Aßmann, M Hahn, M Alkhaled, ... Nature 494 (7437), 361-365, 2013 | 801 | 2013 |
mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype N Herranz, S Gallage, M Mellone, T Wuestefeld, S Klotz, CJ Hanley, ... Nature cell biology 17 (9), 1205-1217, 2015 | 687 | 2015 |
Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis SU Wiemann, A Satyanarayana, M Tsahuridu, HL Tillmann, L Zender, ... The FASEB journal 16 (9), 935-942, 2002 | 655 | 2002 |
The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration B Ritschka, M Storer, A Mas, F Heinzmann, MC Ortells, JP Morton, ... Genes & development 31 (2), 172-183, 2017 | 607 | 2017 |
Yes‐associated protein is an independent prognostic marker in hepatocellular carcinoma MZ Xu, TJ Yao, NPY Lee, IOL Ng, YT Chan, L Zender, SW Lowe, ... Cancer: Interdisciplinary International Journal of the American Cancer …, 2009 | 568 | 2009 |
Caspase 8 small interfering RNA prevents acute liver failure in mice L Zender, S Hütker, C Liedtke, HL Tillmann, S Zender, B Mundt, ... Proceedings of the National Academy of Sciences 100 (13), 7797-7802, 2003 | 524 | 2003 |
Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles S Walz, F Lorenzin, J Morton, KE Wiese, B von Eyss, S Herold, L Rycak, ... Nature 511 (7510), 483-487, 2014 | 512 | 2014 |
An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer L Zender, W Xue, J Zuber, CP Semighini, A Krasnitz, B Ma, P Zender, ... Cell 135 (5), 852-864, 2008 | 503 | 2008 |
Distinct functions of senescence-associated immune responses in liver tumor surveillance and tumor progression T Eggert, K Wolter, J Ji, C Ma, T Yevsa, S Klotz, J Medina-Echeverz, ... Cancer cell 30 (4), 533-547, 2016 | 500 | 2016 |
Identification of a therapeutic strategy targeting amplified FGF19 in liver cancer by Oncogenomic screening ET Sawey, M Chanrion, C Cai, G Wu, J Zhang, L Zender, A Zhao, ... Cancer cell 19 (3), 347-358, 2011 | 491 | 2011 |
NOTCH1 mediates a switch between two distinct secretomes during senescence M Hoare, Y Ito, TW Kang, MP Weekes, NJ Matheson, DA Patten, S Shetty, ... Nature cell biology 18 (9), 979-992, 2016 | 451 | 2016 |
Topoisomerase levels determine chemotherapy response in vitro and in vivo DJ Burgess, J Doles, L Zender, W Xue, B Ma, WR McCombie, GJ Hannon, ... Proceedings of the National Academy of Sciences 105 (26), 9053-9058, 2008 | 384 | 2008 |