Targeting cancer cell mitochondria as a therapeutic approach S Wen, D Zhu, P Huang Future medicinal chemistry 5 (1), 53-67, 2013 | 225 | 2013 |
Application of Fragment Growing and Fragment Linking to the Discovery of Inhibitors of Mycobacterium tuberculosis Pantothenate Synthetase This research was supported by the … AW Hung, HL Silvestre, S Wen, A Ciulli, TL Blundell, C Abell Angewandte Chemie-German Edition 121 (45), 8604, 2009 | 186 | 2009 |
Mining expression and prognosis of topoisomerase isoforms in non-small-cell lung cancer by using Oncomine and Kaplan–Meier plotter GX Hou, P Liu, J Yang, S Wen PloS one 12 (3), e0174515, 2017 | 179 | 2017 |
Xc− inhibitor sulfasalazine sensitizes colorectal cancer to cisplatin by a GSH-dependent mechanism M Ma, G Chen, P Wang, W Lu, C Zhu, M Song, J Yang, S Wen, R Xu, Y Hu, ... Cancer letters 368 (1), 88-96, 2015 | 155 | 2015 |
Pathway-selective sensitization of Mycobacterium tuberculosis for target-based whole-cell screening GL Abrahams, A Kumar, S Savvi, AW Hung, S Wen, C Abell, CE Barry, ... Chemistry & biology 19 (7), 844-854, 2012 | 145 | 2012 |
Inhibition of cancer growth in vitro and in vivo by a novel ROS-modulating agent with ability to eliminate stem-like cancer cells J Wang, B Luo, X Li, W Lu, J Yang, Y Hu, P Huang, S Wen Cell death & disease 8 (6), e2887-e2887, 2017 | 133 | 2017 |
The first biologically active synthetic analogues of FK228, the depsipeptide histone deacetylase inhibitor A Yurek-George, ARL Cecil, AHK Mo, S Wen, H Rogers, F Habens, ... Journal of medicinal chemistry 50 (23), 5720-5726, 2007 | 122 | 2007 |
Micro-RNA-155 is induced by K-Ras oncogenic signal and promotes ROS stress in pancreatic cancer P Wang, C Zhu, M Ma, G Chen, M Song, Z Zeng, W Lu, J Yang, S Wen, ... Oncotarget 6 (25), 21148, 2015 | 121 | 2015 |
Synthesis of Carbazoles via One‐Pot Copper‐Catalyzed Amine Insertion into Cyclic Diphenyleneiodoniums as a Strategy to Generate a Drug‐Like Chemical Library D Zhu, Q Liu, B Luo, M Chen, R Pi, P Huang, S Wen Advanced Synthesis & Catalysis 355 (11‐12), 2172-2178, 2013 | 115 | 2013 |
Mild Cu (I)-catalyzed cascade reaction of cyclic diaryliodoniums, sodium azide, and alkynes: efficient synthesis of triazolophenanthridines Z Liu, D Zhu, B Luo, N Zhang, Q Liu, Y Hu, R Pi, P Huang, S Wen Organic letters 16 (21), 5600-5603, 2014 | 112 | 2014 |
Advances in the studies of roles of Rho/Rho-kinase in diseases and the development of its inhibitors R Guan, X Xu, M Chen, H Hu, H Ge, S Wen, S Zhou, R Pi European journal of medicinal chemistry 70, 613-622, 2013 | 109 | 2013 |
The histone deacetylase inhibitors vorinostat and romidepsin downmodulate IL‐10 expression in cutaneous T‐cell lymphoma cells CE Tiffon, JE Adams, L Van Der Fits, S Wen, PA Townsend, A Ganesan, ... British journal of pharmacology 162 (7), 1590-1602, 2011 | 109 | 2011 |
Discovery of novel N-substituted carbazoles as neuroprotective agents with potent anti-oxidative activity D Zhu, M Chen, M Li, B Luo, Y Zhao, P Huang, F Xue, S Rapposelli, R Pi, ... European journal of medicinal chemistry 68, 81-88, 2013 | 104 | 2013 |
Elimination of stem-like cancer cell side-population by auranofin through modulation of ROS and glycolysis GX Hou, PP Liu, S Zhang, M Yang, J Liao, J Yang, Y Hu, WQ Jiang, ... Cell death & disease 9 (2), 89, 2018 | 100 | 2018 |
Regulation of stem-like cancer cells by glutamine through β-catenin pathway mediated by redox signaling J Liao, PP Liu, G Hou, J Shao, J Yang, K Liu, W Lu, S Wen, Y Hu, ... Molecular cancer 16, 1-13, 2017 | 96 | 2017 |
Total synthesis of cyclomarin C SJ Wen, ZJ Yao Organic Letters 6 (16), 2721-2724, 2004 | 95 | 2004 |
Glyceraldehyde-3-phosphate dehydrogenase promotes cancer growth and metastasis through upregulation of SNAIL expression K Liu, Z Tang, A Huang, P Chen, P Liu, J Yang, W Lu, J Liao, Y Sun, ... International journal of oncology 50 (1), 252-262, 2017 | 93 | 2017 |
Macrolactamization versus macrolactonization: total synthesis of FK228, the depsipeptide histone deacetylase inhibitor S Wen, G Packham, A Ganesan The Journal of organic chemistry 73 (23), 9353-9361, 2008 | 87 | 2008 |
Palladium catalyzed dual C–H functionalization of indoles with cyclic diaryliodoniums, an approach to ring fused carbazole derivatives Y Wu, X Peng, B Luo, F Wu, B Liu, F Song, P Huang, S Wen Organic & Biomolecular Chemistry 12 (48), 9777-9780, 2014 | 82 | 2014 |
Three-component Pd/Cu-catalyzed cascade reactions of cyclic iodoniums, alkynes, and boronic acids: an approach to methylidenefluorenes D Zhu, Y Wu, B Wu, B Luo, A Ganesan, FH Wu, R Pi, P Huang, S Wen Organic letters 16 (9), 2350-2353, 2014 | 79 | 2014 |