| Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation K Moran-Crusio, L Reavie, A Shih, O Abdel-Wahab, D Ndiaye-Lobry, ... Cancer cell 20 (1), 11-24, 2011 | 1450 | 2011 |
| Structural design of engineered costimulation determines tumor rejection kinetics and persistence of CAR T cells Z Zhao, M Condomines, SJC van der Stegen, F Perna, CC Kloss, ... Cancer cell 28 (4), 415-428, 2015 | 814 | 2015 |
| ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression O Abdel-Wahab, M Adli, LM LaFave, J Gao, T Hricik, AH Shih, S Pandey, ... Cancer cell 22 (2), 180-193, 2012 | 690 | 2012 |
| Generation of tumor-targeted human T lymphocytes from induced pluripotent stem cells for cancer therapy M Themeli, CC Kloss, G Ciriello, VD Fedorov, F Perna, M Gonen, ... Nature biotechnology 31 (10), 928-933, 2013 | 502 | 2013 |
| JAK2V617F-mediated phosphorylation of PRMT5 downregulates its methyltransferase activity and promotes myeloproliferation F Liu, X Zhao, F Perna, L Wang, P Koppikar, O Abdel-Wahab, MW Harr, ... Cancer cell 19 (2), 283-294, 2011 | 320 | 2011 |
| Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90 K Moulick, JH Ahn, H Zong, A Rodina, L Cerchietti, EM Gomes DaGama, ... Nature chemical biology 7 (11), 818-826, 2011 | 301 | 2011 |
| Integrating proteomics and transcriptomics for systematic combinatorial chimeric antigen receptor therapy of AML F Perna, SH Berman, RK Soni, J Mansilla-Soto, J Eyquem, M Hamieh, ... Cancer cell 32 (4), 506-519. e5, 2017 | 285 | 2017 |
| Coexpression profile of leukemic stem cell markers for combinatorial targeted therapy in AML S Haubner, F Perna, T Köhnke, C Schmidt, S Berman, C Augsberger, ... Leukemia 33 (1), 64-74, 2019 | 267 | 2019 |
| The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation L Wang, A Gural, XJ Sun, X Zhao, F Perna, G Huang, MA Hatlen, L Vu, ... Science 333 (6043), 765-769, 2011 | 251 | 2011 |
| Donor CD19 CAR T cells exert potent graft-versus-lymphoma activity with diminished graft-versus-host activity A Ghosh, M Smith, SE James, ML Davila, E Velardi, KV Argyropoulos, ... Nature medicine 23 (2), 242-249, 2017 | 223 | 2017 |
| Self-renewal of CD133hi cells by IL6/Notch3 signalling regulates endocrine resistance in metastatic breast cancer P Sansone, C Ceccarelli, M Berishaj, Q Chang, VK Rajasekhar, F Perna, ... Nature communications 7 (1), 10442, 2016 | 170 | 2016 |
| Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells AG Kotini, CJ Chang, I Boussaad, JJ Delrow, EK Dolezal, AB Nagulapally, ... Nature biotechnology 33 (6), 646-655, 2015 | 163 | 2015 |
| Arginine methyltransferase PRMT5 is essential for sustaining normal adult hematopoiesis F Liu, G Cheng, PJ Hamard, S Greenblatt, L Wang, N Man, F Perna, H Xu, ... The Journal of clinical investigation 125 (9), 3532-3544, 2015 | 148 | 2015 |
| Evolution of cancer stem-like cells in endocrine-resistant metastatic breast cancers is mediated by stromal microvesicles P Sansone, M Berishaj, VK Rajasekhar, C Ceccarelli, Q Chang, ... Cancer research 77 (8), 1927-1941, 2017 | 130 | 2017 |
| Beyond transcription factors: how oncogenic signalling reshapes the epigenetic landscape F Liu, L Wang, F Perna, SD Nimer Nature Reviews Cancer 16 (6), 359-372, 2016 | 119 | 2016 |
| PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex LP Vu, F Perna, L Wang, F Voza, ME Figueroa, P Tempst, ... Cell reports 5 (6), 1625-1638, 2013 | 94 | 2013 |
| L3MBTL1 polycomb protein, a candidate tumor suppressor in del (20q12) myeloid disorders, is essential for genome stability N Gurvich, F Perna, A Farina, F Voza, S Menendez, J Hurwitz, SD Nimer Proceedings of the National Academy of Sciences 107 (52), 22552-22557, 2010 | 92 | 2010 |
| Antiviral therapy after complete response to chemotherapy could be efficacious in HCV-positive non-Hodgkin’s lymphoma V La Mura, A De Renzo, F Perna, D D’Agostino, M Masarone, M Romano, ... Journal of hepatology 49 (4), 557-563, 2008 | 86 | 2008 |
| Safety and efficacy of plerixafor dose escalation for the mobilization of CD34+ hematopoietic progenitor cells in patients with sickle cell disease: interim results F Boulad, T Shore, K van Besien, C Minniti, M Barbu-Stevanovic, ... haematologica 103 (5), 770, 2018 | 64 | 2018 |
| Depletion of L3MBTL1 promotes the erythroid differentiation of human hematopoietic progenitor cells: possible role in 20q− polycythemia vera F Perna, N Gurvich, R Hoya-Arias, O Abdel-Wahab, RL Levine, T Asai, ... Blood, The Journal of the American Society of Hematology 116 (15), 2812-2821, 2010 | 60 | 2010 |
