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Qixian Chen
Qixian Chen
Postdoctoral Associate in Department of Chemistry, Massachusetts Institute of Technolog
在 mit.edu 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size
H Cabral, Y Matsumoto, K Mizuno, Q Chen, M Murakami, M Kimura, ...
Nature nanotechnology 6 (12), 815-823, 2011
24692011
Janus “nano-bullets” for magnetic targeting liver cancer chemotherapy
S Dan, L Jing, Z Xiao, P Yue, W Zheng, Z Ming, C Qixian, W Dong, C Li
Biomaterials 100, 118-133, 2016
1682016
Nitroxide-based macromolecular contrast agents with unprecedented transverse relaxivity and stability for magnetic resonance imaging of tumors
HVT Nguyen, Q Chen, JT Paletta, P Harvey, Y Jiang, H Zhang, MD Boska, ...
ACS Central Science 3 (7), 800-811, 2017
1572017
Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors
Z Ge, Q Chen, K Osada, X Liu, TA Tockary, S Uchida, A Dirisala, T Ishii, ...
Biomaterials 35 (10), 3416-3426, 2014
1372014
Pancreatic cancer therapy by systemic administration of VEGF siRNA contained in calcium phosphate/charge-conversional polymer hybrid nanoparticles
F Pittella, K Miyata, Y Maeda, T Suma, S Watanabe, Q Chen, RJ Christie, ...
Journal of controlled release 161 (3), 868-874, 2012
1302012
Tethered PEG crowdedness determining shape and blood circulation profile of polyplex micelle gene carriers
TA Tockary, K Osada, Q Chen, K Machitani, A Dirisala, S Uchida, ...
Macromolecules 46 (16), 6585-6592, 2013
1202013
Self-sufficing H2O2-responsive nanocarriers through tumor-specific H2O2 production for synergistic oxidation-chemotherapy
J Li, W Ke, L Wang, M Huang, W Yin, P Zhang, Q Chen, Z Ge
Journal of Controlled Release 225, 64-74, 2016
1152016
A targeted and stable polymeric nanoformulation enhances systemic delivery of mRNA to tumors
Q Chen, R Qi, X Chen, X Yang, S Wu, H Xiao, W Dong
Molecular Therapy 25 (1), 92-101, 2017
852017
Mitochondria-targeted smart AIEgens: Imaging and therapeutics
H Li, H Kim, C Zhang, S Zeng, Q Chen, L Jia, J Wang, X Peng, J Yoon
Coordination Chemistry Reviews 473, 214818, 2022
842022
PEGylated polyplex with optimized PEG shielding enhances gene introduction in lungs by minimizing inflammatory responses
S Uchida, K Itaka, Q Chen, K Osada, T Ishii, MA Shibata, M Harada-Shiba, ...
Molecular Therapy 20 (6), 1196-1203, 2012
832012
Biodegradable synthetic antimicrobial with aggregation-induced emissive luminogens for temporal antibacterial activity and facile bacteria detection
S Chen, Q Chen, Q Li, J An, P Sun, J Ma, H Gao
Chemistry of Materials 30 (5), 1782-1790, 2018
772018
Nanoparticle conjugates of a highly potent toxin enhance safety and circumvent platinum resistance in ovarian cancer
R Qi, Y Wang, PM Bruno, H Xiao, Y Yu, T Li, S Lauffer, W Wei, Q Chen, ...
Nature communications 8 (1), 2166, 2017
762017
Optimized rod length of polyplex micelles for maximizing transfection efficiency and their performance in systemic gene therapy against stroma-rich pancreatic tumors
A Dirisala, K Osada, Q Chen, TA Tockary, K Machitani, S Osawa, X Liu, ...
Biomaterials 35 (20), 5359-5368, 2014
752014
Ternary polyplex micelles with PEG shells and intermediate barrier to complexed DNA cores for efficient systemic gene delivery
J Li, Q Chen, Z Zha, H Li, K Toh, A Dirisala, Y Matsumoto, K Osada, ...
Journal of Controlled Release 209, 77-87, 2015
712015
Homo-catiomer integration into PEGylated polyplex micelle from block-catiomer for systemic anti-angiogenic gene therapy for fibrotic pancreatic tumors
Q Chen, K Osada, T Ishii, M Oba, S Uchida, TA Tockary, T Endo, Z Ge, ...
Biomaterials 33 (18), 4722-4730, 2012
702012
Dual endogenous stimuli-responsive polyplex micelles as smart two-step delivery nanocarriers for deep tumor tissue penetration and combating drug resistance of cisplatin
J Li, Y Han, Q Chen, H Shi, S ur Rehman, M Siddiq, Z Ge, S Liu
Journal of Materials Chemistry B 2 (13), 1813-1824, 2014
622014
Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting
Q Chen, K Osada, Z Ge, S Uchida, TA Tockary, A Dirisala, A Matsui, K Toh, ...
Biomaterials 113, 253-265, 2017
612017
ABC triblock bottlebrush copolymer-based injectable hydrogels: design, synthesis, and application to expanding the therapeutic index of cancer immunochemotherapy
F Vohidov, LE Milling, Q Chen, W Zhang, S Bhagchandani, HVT Nguyen, ...
Chemical Science 11 (23), 5974-5986, 2020
582020
Bottlebrush polymers with flexible enantiomeric side chains display differential biological properties
HVT Nguyen, Y Jiang, S Mohapatra, W Wang, JC Barnes, NJ Oldenhuis, ...
Nature Chemistry 14 (1), 85-93, 2022
542022
Combination of chondroitin sulfate and polyplex micelles from Poly (ethylene glycol)-poly {N’-[N-(2-aminoethyl)-2-aminoethyl] aspartamide} block copolymer for prolonged in vivo …
S Uchida, K Itaka, Q Chen, K Osada, K Miyata, T Ishii, M Harada-Shiba, ...
Journal of controlled release 155 (2), 296-302, 2011
512011
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