| Therapy for Duchenne muscular dystrophy: renewed optimism from genetic approaches RJ Fairclough, MJ Wood, KE Davies Nature Reviews Genetics 14 (6), 373-378, 2013 | 313 | 2013 |
| Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse JM Tinsley, RJ Fairclough, R Storer, FJ Wilkes, AC Potter, SE Squire, ... PloS one 6 (5), e19189, 2011 | 215 | 2011 |
| The secretory pathway Ca2+/Mn2+-ATPase 2 is a Golgi-localized pump with high affinity for Ca2+ ions J Vanoevelen, L Dode, K Van Baelen, RJ Fairclough, L Missiaen, ... Journal of biological chemistry 280 (24), 22800-22808, 2005 | 159 | 2005 |
| Calcium pumps and keratinocytes: lessons from Darier's disease and Hailey–Hailey disease J Dhitavat, RJ Fairclough, A Hovnanian, SM Burge British Journal of Dermatology 150 (5), 821-828, 2004 | 154 | 2004 |
| Effect of Hailey-Hailey Disease mutations on the function of a new variant of human secretory pathway Ca2+/Mn2+-ATPase (hSPCA1) RJ Fairclough, L Dode, J Vanoevelen, JP Andersen, L Missiaen, ... Journal of Biological Chemistry 278 (27), 24721-24730, 2003 | 137 | 2003 |
| Hailey-Hailey disease: molecular and clinical characterization of novel mutations in the ATP2C1 gene C Dobson-Stone, R Fairclough, E Dunne, J Brown, AP Monaco, ... Journal of investigative dermatology 118 (2), 338-343, 2002 | 131 | 2002 |
| Gata3-deficient mice develop parathyroid abnormalities due to dysregulation of the parathyroid-specific transcription factor Gcm2 IV Grigorieva, S Mirczuk, KU Gaynor, MA Nesbit, EF Grigorieva, Q Wei, ... The Journal of clinical investigation 120 (6), 2144-2155, 2010 | 121 | 2010 |
| Human myometrial genes are differentially expressed in labor: a suppression subtractive hybridization study EC Chan, S Fraser, S Yin, G Yeo, K Kwek, RJ Fairclough, R Smith The Journal of Clinical Endocrinology & Metabolism 87 (6), 2435-2441, 2002 | 114 | 2002 |
| Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin D Li, A Bareja, L Judge, Y Yue, Y Lai, R Fairclough, KE Davies, ... Journal of cell science 123 (12), 2008-2013, 2010 | 110 | 2010 |
| Changes in matrix metalloproteinase (MMP)-2 and MMP-9 in the fetal amnion and chorion during gestation and at term and preterm labor H Yonemoto, CB Young, JT Ross, LL Guilbert, RJ Fairclough, DM Olson Placenta 27 (6-7), 669-677, 2006 | 94 | 2006 |
| Progress in therapy for Duchenne muscular dystrophy RJ Fairclough, A Bareja, KE Davies Experimental physiology 96 (11), 1101-1113, 2011 | 85 | 2011 |
| 11β-Hydroxysteroid dehydrogenase type 1 inhibition in idiopathic intracranial hypertension: a double-blind randomized controlled trial K Markey, J Mitchell, H Botfield, RS Ottridge, T Matthews, A Krishnan, ... Brain Communications 2 (1), fcz050, 2020 | 66 | 2020 |
| 11βHSD1 inhibition with AZD4017 improves lipid profiles and lean muscle mass in idiopathic intracranial hypertension RS Hardy, H Botfield, K Markey, JL Mitchell, Z Alimajstorovic, ... The Journal of Clinical Endocrinology & Metabolism 106 (1), 174-187, 2021 | 53 | 2021 |
| Hailey–Hailey disease: identification of novel mutations in ATP2C1 and effect of missense mutation A528P on protein expression levels RJ Fairclough, L Lonie, K Van Baelen, M Haftek, CS Munro, SM Burge, ... Journal of investigative dermatology 123 (1), 67-71, 2004 | 53 | 2004 |
| Public-private partnerships: compound and data sharing in drug discovery and development AM Davis, O Engkvist, RJ Fairclough, I Feierberg, A Freeman, P Iyer SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (5), 604-619, 2021 | 25 | 2021 |
| Oral 11β-HSD1 inhibitor AZD4017 improves wound healing and skin integrity in adults with type 2 diabetes mellitus: a pilot randomized controlled trial RA Ajjan, EMA Hensor, F Del Galdo, K Shams, A Abbas, RJ Fairclough, ... European journal of endocrinology 186 (4), 441-455, 2022 | 19 | 2022 |
| Discovery and mechanism of action studies of 4, 6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy A Vuorinen, IVL Wilkinson, M Chatzopoulou, B Edwards, SE Squire, ... European Journal of Medicinal Chemistry 220, 113431, 2021 | 14 | 2021 |
| Chronic glucokinase activator treatment activates liver Carbohydrate response element binding protein and improves hepatocyte ATP homeostasis during substrate challenge BE Ford, SS Chachra, A Alshawi, A Brennan, S Harnor, C Cano, DJ Baker, ... Diabetes, Obesity and Metabolism 22 (11), 1985-1994, 2020 | 12 | 2020 |
| Clinic‐ready inhibitor of MMP‐9/‐12 restores sensory and functional decline in rodent models of spinal cord injury Z Ahmed, S Alhajlah, AM Thompson, RJ Fairclough Clinical and Translational Medicine 12 (5), 2022 | 9 | 2022 |
| The GCKR-P446L gene variant predisposes to raised blood cholesterol and lower blood glucose in the P446L mouse-a model for GCKR rs1260326 BE Ford, SS Chachra, K Rodgers, T Moonira, ZH Al-Oanzi, QM Anstee, ... Molecular Metabolism 72, 101722, 2023 | 6 | 2023 |
