Cell-Penetrating Peptides, PepFects, Show No Evidence of Toxicity and Immunogenicity In Vitro and In Vivo J Suhorutsenko, N Oskolkov, P Arukuusk, K Kurrikoff, E Eriste, ... Bioconjugate chemistry 22 (11), 2255-2262, 2011 | 148 | 2011 |
PepFect14 peptide vector for efficient gene delivery in cell cultures KL Veiman, I Mäger, K Ezzat, H Margus, T Lehto, K Langel, K Kurrikoff, ... Molecular pharmaceutics 10 (1), 199-210, 2013 | 102 | 2013 |
New generation of efficient peptide-based vectors, NickFects, for the delivery of nucleic acids P Arukuusk, L Pärnaste, N Oskolkov, DM Copolovici, H Margus, K Padari, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1828 (5), 1365-1373, 2013 | 96 | 2013 |
Translocation of cell-penetrating peptides across the plasma membrane is controlled by cholesterol and microenvironment created by membranous proteins J Pae, P Säälik, L Liivamägi, D Lubenets, P Arukuusk, Ü Langel, M Pooga Journal of Controlled Release 192, 103-113, 2014 | 80 | 2014 |
NickFects, phosphorylated derivatives of transportan 10 for cellular delivery of oligonucleotides N Oskolkov, P Arukuusk, DM Copolovici, S Lindberg, H Margus, K Padari, ... International Journal of Peptide Research and Therapeutics 17, 147-157, 2011 | 66 | 2011 |
Differential endosomal pathways for radically modified peptide vectors P Arukuusk, L Pärnaste, H Margus, NKJ Eriksson, L Vasconcelos, ... Bioconjugate chemistry 24 (10), 1721-1732, 2013 | 64 | 2013 |
Optimization of in vivo DNA delivery with NickFect peptide vectors K Freimann, P Arukuusk, K Kurrikoff, LDF Vasconcelos, KL Veiman, ... Journal of Controlled Release 241, 135-143, 2016 | 57 | 2016 |
Characteristics of cell-penetrating peptide/nucleic acid nanoparticles H Margus, P Arukuusk, U Langel, M Pooga Molecular Pharmaceutics 13 (1), 172-179, 2016 | 56 | 2016 |
The formation of nanoparticles between small interfering RNA and amphipathic cell-penetrating peptides L Pärnaste, P Arukuusk, K Langel, T Tenson, Ü Langel Molecular Therapy-Nucleic Acids 7, 1-10, 2017 | 55 | 2017 |
Effective in vivo gene delivery with reduced toxicity, achieved by charge and fatty acid -modified cell penetrating peptide K Kurrikoff, KL Veiman, K Künnapuu, EM Peets, T Lehto, L Pärnaste, ... Scientific reports 7 (1), 17056, 2017 | 41 | 2017 |
Effects of cargo molecules on membrane perturbation caused by transportan10 based cell-penetrating peptides L Vasconcelos, F Madani, P Arukuusk, L Pärnaste, A Gräslund, Ü Langel Biochimica et Biophysica Acta (BBA)-Biomembranes 1838 (12), 3118-3129, 2014 | 38 | 2014 |
NickFect type of cell-penetrating peptides present enhanced efficiency for microRNA-146a delivery into dendritic cells and during skin inflammation G Carreras-Badosa, J Maslovskaja, K Periyasamy, E Urgard, K Padari, ... Biomaterials 262, 120316, 2020 | 37 | 2020 |
Porous silicon–cell penetrating peptide hybrid nanocarrier for intracellular delivery of oligonucleotides J Rytkonen, P Arukuusk, W Xu, K Kurrikoff, U Langel, VP Lehto, ... Molecular Pharmaceutics 11 (2), 382-390, 2014 | 35 | 2014 |
Enhancement of siRNA transfection by the optimization of fatty acid length and histidine content in the CPP L Porosk, P Arukuusk, K Põhako, K Kurrikoff, K Kiisholts, K Padari, ... Biomaterials science 7 (10), 4363-4374, 2019 | 34 | 2019 |
PepFects and NickFects for the intracellular delivery of nucleic acids P Arukuusk, L Pärnaste, M Hällbrink, Ü Langel Cell-Penetrating Peptides: Methods and Protocols, 303-315, 2015 | 33 | 2015 |
Glycosaminoglycans are required for translocation of amphipathic cell-penetrating peptides across membranes J Pae, L Liivamägi, D Lubenets, P Arukuusk, Ü Langel, M Pooga Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (8), 1860-1867, 2016 | 32 | 2016 |
Cell‐penetrating peptides recruit type A scavenger receptors to the plasma membrane for cellular delivery of nucleic acids C Juks, A Lorents, P Arukuusk, Ü Langel, M Pooga The FASEB Journal 31 (3), 975-988, 2017 | 27 | 2017 |
Formulation of stable and homogeneous cell-penetrating peptide NF55 nanoparticles for efficient gene delivery in vivo K Freimann, P Arukuusk, K Kurrikoff, L Pärnaste, R Raid, A Piirsoo, ... Molecular Therapy-Nucleic Acids 10, 28-35, 2018 | 25 | 2018 |
The role of endocytosis in the uptake and intracellular trafficking of PepFect14–nucleic acid nanocomplexes via class A scavenger receptors C Juks, K Padari, H Margus, A Kriiska, I Etverk, P Arukuusk, K Koppel, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (12), 3205-3216, 2015 | 24 | 2015 |
Methods to follow intracellular trafficking of cell-penetrating peptides L Pärnaste, P Arukuusk, E Zagato, K Braeckmans, Ü Langel Journal of Drug Targeting 24 (6), 508-519, 2016 | 17 | 2016 |