| ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and β-catenin translocation T Maretzky, K Reiss, A Ludwig, J Buchholz, F Scholz, E Proksch, ... Proceedings of the National Academy of Sciences 102 (26), 9182-9187, 2005 | 828 | 2005 |
| ADAM10 cleavage of N‐cadherin and regulation of cell–cell adhesion and β‐catenin nuclear signalling K Reiss, T Maretzky, A Ludwig, T Tousseyn, B De Strooper, D Hartmann, ... The EMBO journal 24 (4), 742-752, 2005 | 610 | 2005 |
| iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS DR McIlwain, PA Lang, T Maretzky, K Hamada, K Ohishi, SK Maney, ... Science 335 (6065), 229-232, 2012 | 368 | 2012 |
| ADAM10 regulates endothelial permeability and T-Cell transmigration by proteolysis of vascular endothelial cadherin B Schulz, J Pruessmeyer, T Maretzky, A Ludwig, CP Blobel, P Saftig, ... Circulation research 102 (10), 1192-1201, 2008 | 344 | 2008 |
| L1 is sequentially processed by two differently activated metalloproteases and presenilin/γ-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowth T Maretzky, M Schulte, A Ludwig, S Rose-John, C Blobel, D Hartmann, ... Molecular and cellular biology 25 (20), 9040-9053, 2005 | 298 | 2005 |
| Phytochemicals perturb membranes and promiscuously alter protein function HI Ingólfsson, P Thakur, KF Herold, EA Hobart, NB Ramsey, X Periole, ... ACS chemical biology 9 (8), 1788-1798, 2014 | 280 | 2014 |
| ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site SM Le Gall, T Maretzky, PDA Issuree, XD Niu, K Reiss, P Saftig, R Khokha, ... Journal of cell science 123 (22), 3913-3922, 2010 | 261 | 2010 |
| ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death M Schulte, K Reiss, M Lettau, T Maretzky, A Ludwig, D Hartmann, ... Cell Death & Differentiation 14 (5), 1040-1049, 2007 | 222 | 2007 |
| iRHOM2 is a critical pathogenic mediator of inflammatory arthritis PDA Issuree, T Maretzky, DR McIlwain, S Monette, X Qing, PA Lang, ... The Journal of clinical investigation 123 (2), 928-932, 2013 | 197 | 2013 |
| iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding T Maretzky, DR McIlwain, PDA Issuree, X Li, J Malapeira, S Amin, ... Proceedings of the National Academy of Sciences 110 (28), 11433-11438, 2013 | 185 | 2013 |
| Phosphatidylserine exposure is required for ADAM17 sheddase function A Sommer, F Kordowski, J Büch, T Maretzky, A Evers, J Andrä, ... Nature communications 7 (1), 11523, 2016 | 183 | 2016 |
| Migration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17 T Maretzky, A Evers, W Zhou, SL Swendeman, PM Wong, S Rafii, K Reiss, ... Nature communications 2 (1), 229, 2011 | 171 | 2011 |
| iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling X Li, T Maretzky, G Weskamp, S Monette, X Qing, PDA Issuree, ... Proceedings of the National Academy of Sciences 112 (19), 6080-6085, 2015 | 162 | 2015 |
| Regulated ADAM10-dependent ectodomain shedding of γ-protocadherin C3 modulates cell-cell adhesion K Reiss, T Maretzky, IG Haas, M Schulte, A Ludwig, M Frank, P Saftig Journal of Biological Chemistry 281 (31), 21735-21744, 2006 | 141 | 2006 |
| ADAM10-mediated E-cadherin release is regulated by proinflammatory cytokines and modulates keratinocyte cohesion in eczematous dermatitis T Maretzky, F Scholz, B Köten, E Proksch, P Saftig, K Reiss Journal of Investigative Dermatology 128 (7), 1737-1746, 2008 | 103 | 2008 |
| The functional maturation of a disintegrin and metalloproteinase (ADAM) 9, 10, and 17 requires processing at a newly identified proprotein convertase (PC) cleavage site E Wong, T Maretzky, Y Peleg, CP Blobel, I Sagi Journal of Biological Chemistry 290 (19), 12135-12146, 2015 | 89 | 2015 |
| A transforming Src mutant increases the bioavailability of EGFR ligands via stimulation of the cell-surface metalloproteinase ADAM17 T Maretzky, W Zhou, XY Huang, CP Blobel Oncogene 30 (5), 611-618, 2011 | 78 | 2011 |
| Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17 SK Maney, DR McIlwain, R Polz, AA Pandyra, B Sundaram, D Wolff, ... Science signaling 8 (401), ra109-ra109, 2015 | 67 | 2015 |
| Characterization of the catalytic activity of the membrane-anchored metalloproteinase ADAM15 in cell-based assays T Maretzky, G Yang, O Ouerfelli, CM Overall, S Worpenberg, U Hassiepen, ... Biochemical Journal 420 (1), 105-113, 2009 | 66 | 2009 |
| ADAM17 controls endochondral ossification by regulating terminal differentiation of chondrocytes KC Hall, D Hill, M Otero, DA Plumb, D Froemel, CL Dragomir, T Maretzky, ... Molecular and cellular biology 33 (16), 3077-3090, 2013 | 56 | 2013 |
