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Binding pathway determines norepinephrine selectivity for the human β1AR over β2AR X Xu, J Kaindl, MJ Clark, H Hübner, K Hirata, RK Sunahara, P Gmeiner, ... Cell Research 31 (5), 569-579, 2021 | 84 | 2021 |
An allosteric modulator binds to a conformational hub in the β2 adrenergic receptor X Liu, J Kaindl, M Korczynska, A Stößel, D Dengler, M Stanek, H Hübner, ... Nature chemical biology 16 (7), 749-755, 2020 | 66 | 2020 |
Silencing of retrotransposon-derived imprinted gene RTL1 is the main cause for postimplantational failures in mammalian cloning D Yu, J Wang, H Zou, T Feng, L Chen, J Li, X Qi, Z Li, X Duan, C Xu, ... Proceedings of the National Academy of Sciences 115 (47), E11071-E11080, 2018 | 41 | 2018 |
Convergent and divergent genetic changes in the genome of Chinese and European pigs J Wang, H Zou, L Chen, X Long, J Lan, W Liu, L Ma, C Wang, X Xu, L Ren, ... Scientific reports 7 (1), 8662, 2017 | 13 | 2017 |
Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics X Xu, J Shonberg, J Kaindl, MJ Clark, A Stößel, L Maul, D Mayer, ... Nature communications 14 (1), 2138, 2023 | 9 | 2023 |
Structural and functional characterization of the endogenous agonist for orphan receptor GPR3 G Chen, N Staffen, Z Wu, X Xu, J Pan, A Inoue, T Shi, P Gmeiner, Y Du, ... Cell Research 34 (3), 262-265, 2024 | 3 | 2024 |
Bitopic Ligands Support the Presence of a Metastable Binding Site at the β2 Adrenergic Receptor BI Gaiser, M Danielsen, X Xu, K Røpke Jørgensen, P Fronik, ... Journal of Medicinal Chemistry, 2024 | | 2024 |