| CTLA-4-mediated inhibition in regulation of T cell responses: mechanisms and manipulation in tumor immunotherapy CA Chambers, MS Kuhns, JG Egen, JP Allison Annual review of immunology 19 (1), 565-594, 2001 | 1273 | 2001 |
| CTLA-4: new insights into its biological function and use in tumor immunotherapy JG Egen, MS Kuhns, JP Allison Nature immunology 3 (7), 611-618, 2002 | 1056 | 2002 |
| T cells use two directionally distinct pathways for cytokine secretion M Huse, BF Lillemeier, MS Kuhns, DS Chen, MM Davis Nature immunology 7 (3), 247-255, 2006 | 502 | 2006 |
| Deconstructing the form and function of the TCR/CD3 complex MS Kuhns, MM Davis, KC Garcia Immunity 24 (2), 133-139, 2006 | 356 | 2006 |
| Spatial and temporal dynamics of T cell receptor signaling with a photoactivatable agonist M Huse, LO Klein, AT Girvin, JM Faraj, QJ Li, MS Kuhns, MM Davis Immunity 27 (1), 76-88, 2007 | 271 | 2007 |
| γδ T cells recognize a microbial encoded B cell antigen to initiate a rapid antigen-specific interleukin-17 response X Zeng, YL Wei, J Huang, EW Newell, H Yu, BA Kidd, MS Kuhns, ... Immunity 37 (3), 524-534, 2012 | 223 | 2012 |
| Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates primary and secondary peptide-specific CD4+ T cell responses CA Chambers, MS Kuhns, JP Allison Proceedings of the National Academy of Sciences 96 (15), 8603-8608, 1999 | 156 | 1999 |
| A mechanical switch couples T cell receptor triggering to the cytoplasmic juxtamembrane regions of CD3ζζ MS Lee, CR Glassman, NR Deshpande, HB Badgandi, HL Parrish, ... Immunity 43 (2), 227-239, 2015 | 120 | 2015 |
| Disruption of extracellular interactions impairs T cell receptor-CD3 complex stability and signaling MS Kuhns, MM Davis Immunity 26 (3), 357-369, 2007 | 120 | 2007 |
| TCR signaling emerges from the sum of many parts MS Kuhns, MM Davis Frontiers in immunology 3, 159, 2012 | 103 | 2012 |
| Evidence for a functional sidedness to the αβTCR MS Kuhns, AT Girvin, LO Klein, R Chen, KDC Jensen, EW Newell, ... Proceedings of the National Academy of Sciences 107 (11), 5094-5099, 2010 | 94 | 2010 |
| Piecing together the family portrait of TCR‐CD 3 complexes MS Kuhns, HB Badgandi Immunological reviews 250 (1), 120-143, 2012 | 85 | 2012 |
| Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c–I-Ek EW Newell, LK Ely, AC Kruse, PA Reay, SN Rodriguez, AE Lin, MS Kuhns, ... The Journal of Immunology 186 (10), 5823-5832, 2011 | 81 | 2011 |
| Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates the size, reactivity, and function of a primed pool of CD4+ T cells MS Kuhns, V Epshteyn, RA Sobel, JP Allison Proceedings of the National Academy of Sciences 97 (23), 12711-12716, 2000 | 76 | 2000 |
| Domain-swapped T cell receptors improve the safety of TCR gene therapy MT Bethune, MH Gee, M Bunse, MS Lee, EH Gschweng, MS Pagadala, ... Elife 5, e19095, 2016 | 60 | 2016 |
| The safety on the TCR trigger MS Kuhns, MM Davis Cell 135 (4), 594-596, 2008 | 59 | 2008 |
| Self-recognition drives the preferential accumulation of promiscuous CD4+ T-cells in aged mice NR Deshpande, HL Parrish, MS Kuhns Elife 4, e05949, 2015 | 36 | 2015 |
| Functional evidence for TCR-intrinsic specificity for MHCII HL Parrish, NR Deshpande, J Vasic, MS Kuhns Proceedings of the National Academy of Sciences 113 (11), 3000-3005, 2016 | 32 | 2016 |
| Reciprocal TCR-CD3 and CD4 engagement of a nucleating pMHCII stabilizes a functional receptor macrocomplex CR Glassman, HL Parrish, MS Lee, MS Kuhns Cell reports 22 (5), 1263-1275, 2018 | 28 | 2018 |
| A transmembrane domain GGxxG motif in CD4 contributes to its Lck-independent function but does not mediate CD4 dimerization HL Parrish, CR Glassman, MM Keenen, NR Deshpande, MP Bronnimann, ... PLoS One 10 (7), e0132333, 2015 | 26 | 2015 |
