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Ingo Bichlmaier
Ingo Bichlmaier
Senior Toxicologist, European Chemicals Agency
在 echa.europa.eu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
UDP-glucuronosyltransferases (UGTs) 2B7 and UGT2B17 display converse specificity in testosterone and epitestosterone glucuronidation, whereas UGT2A1 conjugates both androgens …
T Sten, I Bichlmaier, T Kuuranne, A Leinonen, J Yli-Kauhaluoma, M Finel
Drug Metabolism and Disposition 37 (2), 417-423, 2009
1272009
Stereochemical sensitivity of the human UDP-glucuronosyltransferases 2B7 and 2B17
I Bichlmaier, A Siiskonen, M Finel, J Yli-Kauhaluoma
Journal of medicinal chemistry 49 (5), 1818-1827, 2006
342006
Isoform-selective inhibition of the human UDP-glucuronosyltransferase 2B7 by isolongifolol derivatives
I Bichlmaier, M Kurkela, T Joshi, A Siiskonen, T Rüffer, H Lang, ...
Journal of medicinal chemistry 50 (11), 2655-2664, 2007
192007
Molecularly imprinted polymers for eliminating metabolites
T Fichert, I Bichlmaier
US Patent App. 14/178,677, 2014
112014
Eudismic analysis of tricyclic sesquiterpenoid alcohols: Lead structures for the design of potent inhibitors of the human UDP-glucuronosyltransferase 2B7
I Bichlmaier, M Kurkela, A Siiskonen, M Finel, J Yli-Kauhaluoma
Bioorganic chemistry 35 (5), 386-400, 2007
112007
Chiral distinction between the enantiomers of bicyclic alcohols by UDP-glucuronosyltransferases 2B7 and 2B17
I Bichlmaier, A Siiskonen, M Kurkela, M Finel, J Yli-Kauhaluoma
Walter de Gruyter 387 (4), 407-416, 2006
102006
Molecularly imprinted polymers for eliminating metabolites
T Fichert, I Bichlmaier
US Patent App. 13/635,245, 2013
92013
Pharmaceutical compositions containing substituted 6-deoxy-6-sulfanylcyclodextrin
T Fichert, J Gerber, I Bichlmaier
US Patent 9,066,970, 2015
82015
Pharmaceutical composition containing cyclodextrin copolymer
T Fichert, I Bichlmaier
US Patent App. 13/635,228, 2013
82013
Potent Inhibitors of the Human UDP‐Glucuronosyltransferase 2B7 Derived from the Sesquiterpenoid Alcohol Longifolol
I Bichlmaier, M Kurkela, T Joshi, A Siiskonen, T Rüffer, H Lang, M Finel, ...
ChemMedChem: Chemistry Enabling Drug Discovery 2 (6), 881-889, 2007
82007
The importance of study design in investigating intrinsic developmental toxic properties of substances in new studies under the REACH and CLP Regulations in the European Union
IB Kati Hellsten, Bohumila Bichlmaier Suchanová, Virve Sihvola, Ulla ...
Current Opinion in Toxicology 34, 2023
62023
Stereochemical and Steric Control of the UDP‐Glucuronosyltransferase‐Catalyzed Conjugation Reaction: A Rational Approach for the Design of Inhibitors for the Human UGT2B7
I Bichlmaier, M Finel, W Sippl, J Yli‐Kauhaluoma
ChemMedChem: Chemistry Enabling Drug Discovery 2 (12), 1730-1740, 2007
62007
UGT2B7 and UGT2B17 display converse specificity in testosterone and epitestosterone glucuronidation, whereas UGT2A1 conjugates both androgens similarly
T Sten, I Bichlmaier, T Kuuranne, A Leinonen, J Yli-Kauhaluoma, M Finel
Drug Metabolism and Disposition, 2008
42008
A non-clinical and clinical IUCLID database for 530 pharmaceuticals (part I): Methodological aspects of its development
M Evangelisti, MD Parenti, G Varchi, J Franco, J Vom Brocke, ...
Regulatory Toxicology and Pharmacology 142, 105416, 2023
12023
Differences in endocrine and reproductive responses to substance exposure across generations: highlighting the importance of complementary findings
I Bichlmaier
Archives of Toxicology 98 (10), 3215-3230, 2024
2024
Evaluating the conduct and reporting of the T-cell dependent antibody response in the Extended One-Generation Reproductive Toxicity study provided under the EU REACH regulation
RJ Vandebriel, B Hakkert, JLA Pennings, LH Rossi, I Bichlmaier, W Bil
Critical Reviews in Toxicology 54 (7), 476-484, 2024
2024
Revealing hidden challenges: an in-depth evaluation of Anogenital Distance (AGD) and Areola/Nipple Retention (NR) assessments in EOGRT Studies, with implications for regulatory …
M Axelstad, U Hass, I Bichlmaier, U Simanainen, C Beausoleil, J Deweirdt, ...
Toxicology Letters 399 (Supplement 2), S374, 2024
2024
Regulatory aspects under REACH relating to the developmental immunotoxicity (DIT) cohort in the extended one-generation reproductive toxicity study (EOGRTS)
I Bichlmaier, L Rossi, P Sakha, O Leppäranta, H Huuskonen
Toxicology Letters 295, S50, 2018
2018
Link between narcotic effects of solvents and (developmental) neurotoxicity
I Bichlmaier, DMG De Groot, H Huuskonen
Reproductive Toxicology 72, 32-33, 2017
2017
Esterified Polysaccharide Osmotics
D Fenn, T Fichert, T Schweitzer, I Bichlmaier
US Patent App. 15/482,252, 2017
2017
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