UDP-glucuronosyltransferases (UGTs) 2B7 and UGT2B17 display converse specificity in testosterone and epitestosterone glucuronidation, whereas UGT2A1 conjugates both androgens … T Sten, I Bichlmaier, T Kuuranne, A Leinonen, J Yli-Kauhaluoma, M Finel Drug Metabolism and Disposition 37 (2), 417-423, 2009 | 127 | 2009 |
Stereochemical sensitivity of the human UDP-glucuronosyltransferases 2B7 and 2B17 I Bichlmaier, A Siiskonen, M Finel, J Yli-Kauhaluoma Journal of medicinal chemistry 49 (5), 1818-1827, 2006 | 34 | 2006 |
Isoform-selective inhibition of the human UDP-glucuronosyltransferase 2B7 by isolongifolol derivatives I Bichlmaier, M Kurkela, T Joshi, A Siiskonen, T Rüffer, H Lang, ... Journal of medicinal chemistry 50 (11), 2655-2664, 2007 | 19 | 2007 |
Molecularly imprinted polymers for eliminating metabolites T Fichert, I Bichlmaier US Patent App. 14/178,677, 2014 | 11 | 2014 |
Eudismic analysis of tricyclic sesquiterpenoid alcohols: Lead structures for the design of potent inhibitors of the human UDP-glucuronosyltransferase 2B7 I Bichlmaier, M Kurkela, A Siiskonen, M Finel, J Yli-Kauhaluoma Bioorganic chemistry 35 (5), 386-400, 2007 | 11 | 2007 |
Chiral distinction between the enantiomers of bicyclic alcohols by UDP-glucuronosyltransferases 2B7 and 2B17 I Bichlmaier, A Siiskonen, M Kurkela, M Finel, J Yli-Kauhaluoma Walter de Gruyter 387 (4), 407-416, 2006 | 10 | 2006 |
Molecularly imprinted polymers for eliminating metabolites T Fichert, I Bichlmaier US Patent App. 13/635,245, 2013 | 9 | 2013 |
Pharmaceutical compositions containing substituted 6-deoxy-6-sulfanylcyclodextrin T Fichert, J Gerber, I Bichlmaier US Patent 9,066,970, 2015 | 8 | 2015 |
Pharmaceutical composition containing cyclodextrin copolymer T Fichert, I Bichlmaier US Patent App. 13/635,228, 2013 | 8 | 2013 |
Potent Inhibitors of the Human UDP‐Glucuronosyltransferase 2B7 Derived from the Sesquiterpenoid Alcohol Longifolol I Bichlmaier, M Kurkela, T Joshi, A Siiskonen, T Rüffer, H Lang, M Finel, ... ChemMedChem: Chemistry Enabling Drug Discovery 2 (6), 881-889, 2007 | 8 | 2007 |
The importance of study design in investigating intrinsic developmental toxic properties of substances in new studies under the REACH and CLP Regulations in the European Union IB Kati Hellsten, Bohumila Bichlmaier Suchanová, Virve Sihvola, Ulla ... Current Opinion in Toxicology 34, 2023 | 6 | 2023 |
Stereochemical and Steric Control of the UDP‐Glucuronosyltransferase‐Catalyzed Conjugation Reaction: A Rational Approach for the Design of Inhibitors for the Human UGT2B7 I Bichlmaier, M Finel, W Sippl, J Yli‐Kauhaluoma ChemMedChem: Chemistry Enabling Drug Discovery 2 (12), 1730-1740, 2007 | 6 | 2007 |
UGT2B7 and UGT2B17 display converse specificity in testosterone and epitestosterone glucuronidation, whereas UGT2A1 conjugates both androgens similarly T Sten, I Bichlmaier, T Kuuranne, A Leinonen, J Yli-Kauhaluoma, M Finel Drug Metabolism and Disposition, 2008 | 4 | 2008 |
A non-clinical and clinical IUCLID database for 530 pharmaceuticals (part I): Methodological aspects of its development M Evangelisti, MD Parenti, G Varchi, J Franco, J Vom Brocke, ... Regulatory Toxicology and Pharmacology 142, 105416, 2023 | 1 | 2023 |
Differences in endocrine and reproductive responses to substance exposure across generations: highlighting the importance of complementary findings I Bichlmaier Archives of Toxicology 98 (10), 3215-3230, 2024 | | 2024 |
Evaluating the conduct and reporting of the T-cell dependent antibody response in the Extended One-Generation Reproductive Toxicity study provided under the EU REACH regulation RJ Vandebriel, B Hakkert, JLA Pennings, LH Rossi, I Bichlmaier, W Bil Critical Reviews in Toxicology 54 (7), 476-484, 2024 | | 2024 |
Revealing hidden challenges: an in-depth evaluation of Anogenital Distance (AGD) and Areola/Nipple Retention (NR) assessments in EOGRT Studies, with implications for regulatory … M Axelstad, U Hass, I Bichlmaier, U Simanainen, C Beausoleil, J Deweirdt, ... Toxicology Letters 399 (Supplement 2), S374, 2024 | | 2024 |
Regulatory aspects under REACH relating to the developmental immunotoxicity (DIT) cohort in the extended one-generation reproductive toxicity study (EOGRTS) I Bichlmaier, L Rossi, P Sakha, O Leppäranta, H Huuskonen Toxicology Letters 295, S50, 2018 | | 2018 |
Link between narcotic effects of solvents and (developmental) neurotoxicity I Bichlmaier, DMG De Groot, H Huuskonen Reproductive Toxicology 72, 32-33, 2017 | | 2017 |
Esterified Polysaccharide Osmotics D Fenn, T Fichert, T Schweitzer, I Bichlmaier US Patent App. 15/482,252, 2017 | | 2017 |