| Roles and regulation of secretory and lysosomal acid sphingomyelinase RW Jenkins, D Canals, YA Hannun Cellular signalling 21 (6), 836-846, 2009 | 353 | 2009 |
| Drug targeting of sphingolipid metabolism: sphingomyelinases and ceramidases D Canals, DM Perry, RW Jenkins, YA Hannun British journal of pharmacology 163 (4), 694-712, 2011 | 199 | 2011 |
| Sphingosine‐1‐phosphate receptor 2 M Adada, D Canals, YA Hannun, LM Obeid The FEBS journal 280 (24), 6354-6366, 2013 | 166 | 2013 |
| Regulated secretion of acid sphingomyelinase: implications for selectivity of ceramide formation RW Jenkins, D Canals, J Idkowiak-Baldys, F Simbari, P Roddy, DM Perry, ... Journal of Biological Chemistry 285 (46), 35706-35718, 2010 | 155 | 2010 |
| Sphingolipids in mitochondria MJ Hernández-Corbacho, MF Salama, D Canals, CE Senkal, LM Obeid Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2017 | 124 | 2017 |
| Inhibitors of the sphingomyelin cycle: Sphingomyelin synthases and sphingomyelinases M Adada, C Luberto, D Canals Chemistry and physics of lipids 197, 45-59, 2016 | 122 | 2016 |
| Synthesis and biological properties of Pachastrissamine (jaspine B) and diastereoisomeric jaspines D Canals, D Mormeneo, G Fabriàs, A Llebaria, J Casas, A Delgado Bioorganic & medicinal chemistry 17 (1), 235-241, 2009 | 120 | 2009 |
| Intracellular sphingosine kinase 2–derived sphingosine-1-phosphate mediates epidermal growth factor–induced ezrin-radixin-moesin phosphorylation and cancer cell invasion MM Adada, D Canals, N Jeong, AD Kelkar, M Hernandez-Corbacho, ... The FASEB Journal 29 (11), 4654, 2015 | 81 | 2015 |
| Differential effects of ceramide and sphingosine 1-phosphate on ERM phosphorylation: probing sphingolipid signaling at the outer plasma membrane D Canals, RW Jenkins, P Roddy, MJ Hernández-Corbacho, LM Obeid, ... Journal of Biological Chemistry 285 (42), 32476-32485, 2010 | 81 | 2010 |
| On-tissue localization of ceramides and other sphingolipids by MALDI mass spectrometry imaging EE Jones, S Dworski, D Canals, J Casas, G Fabrias, D Schoenling, ... Analytical chemistry 86 (16), 8303-8311, 2014 | 78 | 2014 |
| Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice S Alsamman, SA Christenson, A Yu, NME Ayad, MS Mooring, JM Segal, ... Science translational medicine 12 (557), eaay8798, 2020 | 77 | 2020 |
| Sphingolipid regulation of ezrin, radixin, and moesin proteins family: implications for cell dynamics M Adada, D Canals, YA Hannun, LM Obeid Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2014 | 75 | 2014 |
| A novel mechanism of lysosomal acid sphingomyelinase maturation: requirement for carboxyl-terminal proteolytic processing RW Jenkins, J Idkowiak-Baldys, F Simbari, D Canals, P Roddy, CD Riner, ... Journal of Biological Chemistry 286 (5), 3777-3788, 2011 | 72 | 2011 |
| P38 delta MAPK promotes breast cancer progression and lung metastasis by enhancing cell proliferation and cell detachment M Wada, D Canals, M Adada, N Coant, MF Salama, KL Helke, JS Arthur, ... Oncogene 36 (47), 6649-6657, 2017 | 70 | 2017 |
| Sphingosine 1-phosphate induces filopodia formation through S1PR2 activation of ERM proteins KAO Gandy, D Canals, M Adada, M Wada, P Roddy, AJ Snider, ... Biochemical Journal 449 (3), 661-672, 2013 | 69 | 2013 |
| Tumor necrosis factor-α (TNFα)-induced ceramide generation via ceramide synthases regulates loss of focal adhesion kinase (FAK) and programmed cell death MJ Hernández-Corbacho, D Canals, MM Adada, M Liu, CE Senkal, JK Yi, ... Journal of Biological Chemistry 290 (42), 25356-25373, 2015 | 67 | 2015 |
| Protein phosphatase 1α mediates ceramide-induced ERM protein dephosphorylation: a novel mechanism independent of phosphatidylinositol 4, 5-biphosphate (PIP2) and myosin/ERM … D Canals, P Roddy, YA Hannun Journal of Biological Chemistry 287 (13), 10145-10155, 2012 | 65 | 2012 |
| Anterograde and retrograde transport of neutral sphingomyelinase-2 between the Golgi and the plasma membrane D Milhas, CJ Clarke, J Idkowiak-Baldys, D Canals, YA Hannun Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2010 | 63 | 2010 |
| Visualizing bioactive ceramides D Canals, S Salamone, YA Hannun Chemistry and physics of lipids 216, 142-151, 2018 | 60 | 2018 |
| Sphingosine kinase 1 regulates tumor necrosis factor-mediated RANTES induction through p38 mitogen-activated protein kinase but independently of nuclear factor κB activation MM Adada, KA Orr-Gandy, AJ Snider, D Canals, YA Hannun, LM Obeid, ... Journal of Biological Chemistry 288 (38), 27667-27679, 2013 | 53 | 2013 |
Yusuf A HannunDirector, Stony Brook Cancer Center在 sbumed.org 的电子邮件经过验证
Yusuf A HannunDirector, Stony Brook Cancer Center在 sbumed.org 的电子邮件经过验证
Lina Obeidprofessor在 musc.edu 的电子邮件经过验证