PRMT5 regulates DNA repair by controlling the alternative splicing of histone-modifying enzymes PJ Hamard, GE Santiago, F Liu, DL Karl, C Martinez, N Man, ... Cell reports 24 (10), 2643-2657, 2018 | 173 | 2018 |
Arginine methyltransferase PRMT5 is essential for sustaining normal adult hematopoiesis F Liu, G Cheng, PJ Hamard, S Greenblatt, L Wang, N Man, F Perna, H Xu, ... The Journal of clinical investigation 125 (9), 3532-3544, 2015 | 153 | 2015 |
Chromatin modifiers and the promise of epigenetic therapy in acute leukemia SM Greenblatt, SD Nimer Leukemia 28 (7), 1396-1406, 2014 | 109 | 2014 |
Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model S Greenblatt, L Li, C Slape, B Nguyen, R Novak, A Duffield, D Huso, ... Blood, The Journal of the American Society of Hematology 119 (12), 2883-2894, 2012 | 95 | 2012 |
CARM1 is essential for myeloid leukemogenesis but dispensable for normal hematopoiesis SM Greenblatt, N Man, PJ Hamard, T Asai, D Karl, C Martinez, D Bilbao, ... Cancer cell 33 (6), 1111-1127. e5, 2018 | 71 | 2018 |
Arginine methyltransferases in normal and malignant hematopoiesis SM Greenblatt, F Liu, SD Nimer Experimental hematology 44 (6), 435-441, 2016 | 67 | 2016 |
All-trans retinoic acid synergizes with FLT3 inhibition to eliminate FLT3/ITD+ leukemia stem cells in vitro and in vivo HS Ma, SM Greenblatt, CM Shirley, AS Duffield, JK Bruner, L Li, B Nguyen, ... Blood, The Journal of the American Society of Hematology 127 (23), 2867-2878, 2016 | 57 | 2016 |
Loss of the wild-type allele contributes to myeloid expansion and disease aggressiveness in FLT3/ITD knockin mice L Li, E Bailey, S Greenblatt, D Huso, D Small Blood, The Journal of the American Society of Hematology 118 (18), 4935-4945, 2011 | 51 | 2011 |
Caspase-3 controls AML1-ETO–driven leukemogenesis via autophagy modulation in a ULK1-dependent manner N Man, Y Tan, XJ Sun, F Liu, G Cheng, SM Greenblatt, C Martinez, ... Blood, The Journal of the American Society of Hematology 129 (20), 2782-2792, 2017 | 50 | 2017 |
TAF1 plays a critical role in AML1-ETO driven leukemogenesis Y Xu, N Man, D Karl, C Martinez, F Liu, J Sun, CJ Martinez, GM Martin, ... Nature communications 10 (1), 4925, 2019 | 49 | 2019 |
NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease R Rau, D Magoon, S Greenblatt, L Li, C Annesley, AS Duffield, D Huso, ... Experimental hematology 42 (2), 101-113. e5, 2014 | 42 | 2014 |
Histone-binding of DPF2 mediates its repressive role in myeloid differentiation FM Huber, SM Greenblatt, AM Davenport, C Martinez, Y Xu, LP Vu, ... Proceedings of the National Academy of Sciences 114 (23), 6016-6021, 2017 | 39 | 2017 |
Loss of p300 accelerates MDS-associated leukemogenesis G Cheng, F Liu, T Asai, F Lai, N Man, H Xu, S Chen, S Greenblatt, ... Leukemia 31 (6), 1382-1390, 2017 | 39 | 2017 |
Tet2 regulates osteoclast differentiation by interacting with Runx1 and maintaining genomic 5-hydroxymethylcytosine (5hmC) Y Chu, Z Zhao, DW Sant, G Zhu, SM Greenblatt, L Liu, J Wang, Z Cao, ... Genomics, Proteomics and Bioinformatics 16 (3), 172-186, 2018 | 27 | 2018 |
Loss of Asxl2 leads to myeloid malignancies in mice J Li, F He, P Zhang, S Chen, H Shi, Y Sun, Y Guo, H Yang, N Man, ... Nature communications 8 (1), 15456, 2017 | 27 | 2017 |
TTT-3002 is a novel FLT3 tyrosine kinase inhibitor with activity against FLT3-associated leukemias in vitro and in vivo H Ma, B Nguyen, L Li, S Greenblatt, A Williams, M Zhao, M Levis, ... Blood, The Journal of the American Society of Hematology 123 (10), 1525-1534, 2014 | 24 | 2014 |
Covalent modifications of RUNX proteins: structure affects function E Blumenthal, S Greenblatt, G Huang, K Ando, Y Xu, SD Nimer RUNX Proteins in Development and Cancer, 33-44, 2017 | 15 | 2017 |
CARM1/PRMT4 as a Novel Therapeutic Target for AML S Greenblatt, N Man, PJ Hamard, C Martinez, Y Xu, F Liu, JM Watts, ... Blood 130, 241, 2017 | 3 | 2017 |
FLT3 inhibition and retinoid signaling overcome stromal protection to target FLT3/ITD-expressing leukemia stem cells in the bone marrow microenvironment HS Ma, ME McCray, CM Shirley, AS Duffield, JK Bruner, L Li, B Nguyen, ... Blood 126 (23), 790, 2015 | 3 | 2015 |
FLT3 in lineage specification and plasticity S Greenblatt, D Small Oncotarget 3 (5), 576, 2012 | 2 | 2012 |