关注
Sarah Greenblatt
Sarah Greenblatt
Principal Scientist, Cancer Therapeutics, Novartis-GNF
在 gnf.org 的电子邮件经过验证
标题
引用次数
引用次数
年份
PRMT5 regulates DNA repair by controlling the alternative splicing of histone-modifying enzymes
PJ Hamard, GE Santiago, F Liu, DL Karl, C Martinez, N Man, ...
Cell reports 24 (10), 2643-2657, 2018
1732018
Arginine methyltransferase PRMT5 is essential for sustaining normal adult hematopoiesis
F Liu, G Cheng, PJ Hamard, S Greenblatt, L Wang, N Man, F Perna, H Xu, ...
The Journal of clinical investigation 125 (9), 3532-3544, 2015
1532015
Chromatin modifiers and the promise of epigenetic therapy in acute leukemia
SM Greenblatt, SD Nimer
Leukemia 28 (7), 1396-1406, 2014
1092014
Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model
S Greenblatt, L Li, C Slape, B Nguyen, R Novak, A Duffield, D Huso, ...
Blood, The Journal of the American Society of Hematology 119 (12), 2883-2894, 2012
952012
CARM1 is essential for myeloid leukemogenesis but dispensable for normal hematopoiesis
SM Greenblatt, N Man, PJ Hamard, T Asai, D Karl, C Martinez, D Bilbao, ...
Cancer cell 33 (6), 1111-1127. e5, 2018
712018
Arginine methyltransferases in normal and malignant hematopoiesis
SM Greenblatt, F Liu, SD Nimer
Experimental hematology 44 (6), 435-441, 2016
672016
All-trans retinoic acid synergizes with FLT3 inhibition to eliminate FLT3/ITD+ leukemia stem cells in vitro and in vivo
HS Ma, SM Greenblatt, CM Shirley, AS Duffield, JK Bruner, L Li, B Nguyen, ...
Blood, The Journal of the American Society of Hematology 127 (23), 2867-2878, 2016
572016
Loss of the wild-type allele contributes to myeloid expansion and disease aggressiveness in FLT3/ITD knockin mice
L Li, E Bailey, S Greenblatt, D Huso, D Small
Blood, The Journal of the American Society of Hematology 118 (18), 4935-4945, 2011
512011
Caspase-3 controls AML1-ETO–driven leukemogenesis via autophagy modulation in a ULK1-dependent manner
N Man, Y Tan, XJ Sun, F Liu, G Cheng, SM Greenblatt, C Martinez, ...
Blood, The Journal of the American Society of Hematology 129 (20), 2782-2792, 2017
502017
TAF1 plays a critical role in AML1-ETO driven leukemogenesis
Y Xu, N Man, D Karl, C Martinez, F Liu, J Sun, CJ Martinez, GM Martin, ...
Nature communications 10 (1), 4925, 2019
492019
NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease
R Rau, D Magoon, S Greenblatt, L Li, C Annesley, AS Duffield, D Huso, ...
Experimental hematology 42 (2), 101-113. e5, 2014
422014
Histone-binding of DPF2 mediates its repressive role in myeloid differentiation
FM Huber, SM Greenblatt, AM Davenport, C Martinez, Y Xu, LP Vu, ...
Proceedings of the National Academy of Sciences 114 (23), 6016-6021, 2017
392017
Loss of p300 accelerates MDS-associated leukemogenesis
G Cheng, F Liu, T Asai, F Lai, N Man, H Xu, S Chen, S Greenblatt, ...
Leukemia 31 (6), 1382-1390, 2017
392017
Tet2 regulates osteoclast differentiation by interacting with Runx1 and maintaining genomic 5-hydroxymethylcytosine (5hmC)
Y Chu, Z Zhao, DW Sant, G Zhu, SM Greenblatt, L Liu, J Wang, Z Cao, ...
Genomics, Proteomics and Bioinformatics 16 (3), 172-186, 2018
272018
Loss of Asxl2 leads to myeloid malignancies in mice
J Li, F He, P Zhang, S Chen, H Shi, Y Sun, Y Guo, H Yang, N Man, ...
Nature communications 8 (1), 15456, 2017
272017
TTT-3002 is a novel FLT3 tyrosine kinase inhibitor with activity against FLT3-associated leukemias in vitro and in vivo
H Ma, B Nguyen, L Li, S Greenblatt, A Williams, M Zhao, M Levis, ...
Blood, The Journal of the American Society of Hematology 123 (10), 1525-1534, 2014
242014
Covalent modifications of RUNX proteins: structure affects function
E Blumenthal, S Greenblatt, G Huang, K Ando, Y Xu, SD Nimer
RUNX Proteins in Development and Cancer, 33-44, 2017
152017
CARM1/PRMT4 as a Novel Therapeutic Target for AML
S Greenblatt, N Man, PJ Hamard, C Martinez, Y Xu, F Liu, JM Watts, ...
Blood 130, 241, 2017
32017
FLT3 inhibition and retinoid signaling overcome stromal protection to target FLT3/ITD-expressing leukemia stem cells in the bone marrow microenvironment
HS Ma, ME McCray, CM Shirley, AS Duffield, JK Bruner, L Li, B Nguyen, ...
Blood 126 (23), 790, 2015
32015
FLT3 in lineage specification and plasticity
S Greenblatt, D Small
Oncotarget 3 (5), 576, 2012
22012
系统目前无法执行此操作,请稍后再试。
文章 1–20