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Jade Bath
Jade Bath
PhD Candidate, MIT
在 mit.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax …
A Llanos-Cuentas, M Casapia, R Chuquiyauri, JC Hinojosa, N Kerr, ...
The Lancet Infectious Diseases 18 (8), 874-883, 2018
1452018
Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness
BH Stokes, SK Dhingra, K Rubiano, S Mok, J Straimer, NF Gnädig, I Deni, ...
Elife 10, e66277, 2021
1292021
Mucus
A McShane, J Bath, AM Jaramillo, C Ridley, AA Walsh, CM Evans, ...
Current Biology 31 (15), R938-R945, 2021
762021
Identification and Mechanistic Understanding of Dihydroorotate Dehydrogenase Point Mutations in Plasmodium falciparum that Confer in Vitro Resistance to the …
J White, SK Dhingra, X Deng, F El Mazouni, MCS Lee, GA Afanador, ...
ACS infectious diseases 5 (1), 90-101, 2018
522018
The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance
JM Murithi, C Pascal, J Bath, X Boulenc, NF Gnädig, CFA Pasaje, ...
Science Translational Medicine 13 (603), eabg6013, 2021
332021
Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series
MJ Palmer, X Deng, S Watts, G Krilov, A Gerasyuto, S Kokkonda, ...
Journal of Medicinal Chemistry 64 (9), 6085-6136, 2021
332021
Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual …
J Okombo, S Mok, T Qahash, T Yeo, J Bath, LM Orchard, E Owens, I Koo, ...
PLoS pathogens 18 (10), e1010926, 2022
122022
Role of MUC5B during Group B Streptococcal Vaginal Colonization
LR Burcham, JR Bath, CA Werlang, LM Lyon, N Liu, C Evans, K Ribbeck, ...
Mbio 13 (2), e00039-22, 2022
92022
P. falciparum K13 mutations present varying degrees of artemisinin resistance and reduced fitness in African parasites
BH Stokes, K Rubiano, SK Dhingra, S Mok, J Straimer, NF Gnädig, ...
bioRxiv, 2021
42021
Identification of the Plasmodium falciparum acetyl-CoA synthetase as an emerging antiplasmodial drug target
RL Summers, M Vanaerschot, JM Murithi, CF Pasaje, MR Luth, ...
American Journal of Tropical Medicine and Hygiene 101 (5 Suppl. 1), 476-477, 2019
12019
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