| HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130 A Göder, C Emmerich, T Nikolova, N Kiweler, M Schreiber, T Kühl, ... Nature communications 9 (1), 764, 2018 | 70 | 2018 |
| The histone deacetylases HDAC1 and HDAC2 are required for the growth and survival of renal carcinoma cells N Kiweler, B Brill, M Wirth, I Breuksch, T Laguna, C Dietrich, S Strand, ... Archives of toxicology 92, 2227-2243, 2018 | 66 | 2018 |
| Class I histone deacetylases regulate p53/NF-κB crosstalk in cancer cells C Schäfer, A Göder, M Beyer, N Kiweler, N Mahendrarajah, A Rauch, ... Cellular signalling 29, 218-225, 2017 | 53 | 2017 |
| Interstrand crosslink repair as a target for HDAC inhibition T Nikolova, N Kiweler, OH Krämer Trends in pharmacological sciences 38 (9), 822-836, 2017 | 51 | 2017 |
| Sumoylation of HDAC2 promotes NF-κB-dependent gene expression T Wagner, N Kiweler, K Wolff, SK Knauer, A Brandl, P Hemmerich, ... Oncotarget 6 (9), 7123, 2015 | 49 | 2015 |
| Histone deacetylase inhibitors dysregulate DNA repair proteins and antagonize metastasis-associated processes N Kiweler, D Wünsch, M Wirth, N Mahendrarajah, G Schneider, ... Journal of cancer research and clinical oncology 146, 343-356, 2020 | 42 | 2020 |
| Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress N Bonagas, NMS Gustafsson, M Henriksson, P Marttila, R Gustafsson, ... Nature cancer 3 (2), 156-172, 2022 | 39 | 2022 |
| How to distinguish between the activity of HDAC1-3 and HDAC6 with western blot M Beyer, N Kiweler, S Mahboobi, OH Krämer HDAC/HAT Function Assessment and Inhibitor Development: Methods and …, 2017 | 32 | 2017 |
| Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis N Kiweler, C Delbrouck, VI Pozdeev, L Neises, L Soriano-Baguet, K Eiden, ... Nature communications 13 (1), 2699, 2022 | 27 | 2022 |
| Metabolic potential of cancer cells in context of the metastatic cascade M Benzarti, C Delbrouck, L Neises, N Kiweler, J Meiser Cells 9 (9), 2035, 2020 | 20 | 2020 |
| Loss of Wilms tumor 1 protein is a marker for apoptosis in response to replicative stress in leukemic cells M Pons, CM Reichardt, D Hennig, A Nathan, N Kiweler, C Stocking, ... Archives of toxicology 92, 2119-2135, 2018 | 15 | 2018 |
| Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells AC Green, P Marttila, N Kiweler, C Chalkiadaki, E Wiita, V Cookson, ... Nature Metabolism 5 (4), 642-659, 2023 | 13 | 2023 |
| The epigenetic modifier HDAC2 and the checkpoint kinase ATM determine the responses of microsatellite instable colorectal cancer cells to 5-fluorouracil N Kiweler, H Schwarz, A Nguyen, S Matschos, C Mullins, A Piée-Staffa, ... Cell biology and toxicology 39 (5), 2401-2419, 2023 | 8 | 2023 |
| Formate promotes invasion and metastasis in reliance on lipid metabolism C Delbrouck, N Kiweler, O Chen, VI Pozdeev, L Haase, L Neises, A Oudin, ... Cell Reports 42 (9), 2023 | 6 | 2023 |
| HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130. Nat Commun 9 (1): 764 A Göder, C Emmerich, T Nikolova, N Kiweler, M Schreiber, T Kuhl, ... | 6 | 2018 |
| Supplementary methods for" Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress" N Bonagas, N Gustafsson, M Henriksson, P Marttila, R Gustafsson, ... | 2 | 2022 |
| FSMP-09. Formate Promotes Cancer Cell Invasion and Metastasis Via Calcium Signaling C Delbrouck, VI Pozdeev, A Oudin, K Grzyb, L Neises, N Kiweler, ... Neuro-oncology Advances 3 (Suppl 1), i18, 2021 | 2 | 2021 |
| PNUTS at the crossroads of tumorigenesis and metastasis formation N Kiweler, OH Krämer Journal of Thoracic Disease 10 (2), 560, 2018 | 1 | 2018 |
| MTHFD1/2 inhibitor TH9619 targets the DNA damage response and causes cancer-specific folate trapping with an unprecedented therapeutic window P Martilla, AC Green, N Kiweler, C Chalkiadaki, E Wiita, V Cookson, ... MOLECULAR CANCER THERAPEUTICS 22 (12), 2023 | | 2023 |
| Abstract B109: MTHFD1/2 inhibitor TH9619 targets the DNA damage response and causes cancer-specific folate trapping with an unprecedented therapeutic window P Martilla, AC Green, N Kiweler, C Chalkiadaki, E Wiita, V Cookson, ... Molecular Cancer Therapeutics 22 (12_Supplement), B109-B109, 2023 | | 2023 |
