TACI and BAFF-R mediate isotype switching in B cells E Castigli, SA Wilson, S Scott, F Dedeoglu, S Xu, KP Lam, RJ Bram, ... The Journal of experimental medicine 201 (1), 35-39, 2005 | 693 | 2005 |
Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL MJ Benson, SR Dillon, E Castigli, RS Geha, S Xu, KP Lam, RJ Noelle The Journal of Immunology 180 (6), 3655-3659, 2008 | 546 | 2008 |
B-cell maturation protein, which binds the tumor necrosis factor family members BAFF and APRIL, is dispensable for humoral immune responses S Xu, KP Lam Molecular and Cellular Biology 21 (12), 4067-4074, 2001 | 381 | 2001 |
RIG-I, MDA5 and TLR3 synergistically play an important role in restriction of dengue virus infection AMA Nasirudeen, HH Wong, P Thien, S Xu, KP Lam, DX Liu PLoS neglected tropical diseases 5 (1), e926, 2011 | 377 | 2011 |
Single-cell atlas of lineage states, tumor microenvironment, and subtype-specific expression programs in gastric cancer V Kumar, K Ramnarayanan, R Sundar, N Padmanabhan, S Srivastava, ... Cancer discovery 12 (3), 670-691, 2022 | 301 | 2022 |
Phospholipase Cγ2 is critical for Dectin-1-mediated Ca2+ flux and cytokine production in dendritic cells S Xu, J Huo, KG Lee, T Kurosaki, KP Lam Journal of Biological Chemistry 284 (11), 7038-7046, 2009 | 198 | 2009 |
Bruton's tyrosine kinase phosphorylates Toll-like receptor 3 to initiate antiviral response KG Lee, S Xu, ZH Kang, J Huo, M Huang, D Liu, O Takeuchi, S Akira, ... Proceedings of the National Academy of Sciences 109 (15), 5791-5796, 2012 | 169 | 2012 |
B cell development and activation defects resulting in xid-like immunodeficiency in BLNK/SLP-65-deficient mice S Xu, JEL Tan, EPY Wong, A Manickam, S Ponniah, KP Lam International immunology 12 (3), 397-404, 2000 | 168 | 2000 |
The adaptor protein BLNK is required for B cell antigen receptor-induced activation of nuclear factor-κB and cell cycle entry and survival of B lymphocytes JEL Tan, SC Wong, SKE Gan, S Xu, KP Lam Journal of Biological Chemistry 276 (23), 20055-20063, 2001 | 119 | 2001 |
Glycolysis and Oxidative Phosphorylation Play Critical Roles in Natural Killer Cell Receptor-Mediated Natural Killer Cell Functions KP Wang, Z. Guan, D. Wang, S. Chai, L. Y. A. Xu, S. Lam Front Immunol 11, 2020 | 114 | 2020 |
The RNase III enzyme Dicer is essential for germinal center B-cell formation S Xu, K Guo, Q Zeng, J Huo, KP Lam Blood, The Journal of the American Society of Hematology 119 (3), 767-776, 2012 | 108 | 2012 |
Bruton's tyrosine kinase separately regulates NFκB p65RelA activation and cytokine interleukin (IL)-10/IL-12 production in TLR9-stimulated B cells KG Lee, S Xu, ET Wong, V Tergaonkar, KP Lam Journal of Biological Chemistry 283 (17), 11189-11198, 2008 | 103 | 2008 |
BAFF costimulation of Toll‐like receptor‐activatedB‐1 cells LG Ng, CH Ng, B Woehl, APR Sutherland, J Huo, S Xu, F Mackay, ... European journal of immunology 36 (7), 1837-1846, 2006 | 102 | 2006 |
Deficiency in TNFRSF13B (TACI) expands T-follicular helper and germinal center B cells via increased ICOS-ligand expression but impairs plasma cell survival X Ou, S Xu, KP Lam Proceedings of the National Academy of Sciences 109 (38), 15401-15406, 2012 | 101 | 2012 |
Cbp deficiency alters Csk localization in lipid rafts but does not affect T-cell development S Xu, J Huo, JEL Tan, KP Lam Molecular and cellular biology 25 (19), 8486-8495, 2005 | 98 | 2005 |
Activated dectin-1 localizes to lipid raft microdomains for signaling and activation of phagocytosis and cytokine production in dendritic cells S Xu, J Huo, M Gunawan, IH Su, KP Lam Journal of Biological Chemistry 284 (33), 22005-22011, 2009 | 96 | 2009 |
Antibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ameliorates autoimmunity Z Huang, J Wang, X Xu, H Wang, Y Qiao, WC Chu, S Xu, L Chai, F Cottier, ... Nat.Microbiol. 4 (5), 766-773, 2019 | 88 | 2019 |
IL-10 Enhances Human Natural Killer Cell Effector Functions via Metabolic Reprogramming Regulated by mTORC1 Signaling SXKPL Zixi Wang, Di Guan, Jianxin Huo, Subhra K. Biswas, Yuhan Huang ... Frontiers in Immunology, 2021 | 66 | 2021 |
Dok-3 plays a nonredundant role in negative regulation of B-cell activation CH Ng, S Xu, KP Lam Blood, The Journal of the American Society of Hematology 110 (1), 259-266, 2007 | 60 | 2007 |
Mir-17–92 regulates bone marrow homing of plasma cells and production of immunoglobulin G2c S Xu, X Ou, J Huo, K Lim, Y Huang, S Chee, KP Lam Nature Communications 6 (1), 6764, 2015 | 56 | 2015 |