Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains CH Emmerich, A Ordureau, S Strickson, JSC Arthur, PGA Pedrioli, ... Proceedings of the National Academy of Sciences 110 (38), 15247-15252, 2013 | 481 | 2013 |
The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system S Strickson, DG Campbell, CH Emmerich, A Knebel, L Plater, MS Ritorto, ... Biochemical Journal 451 (3), 427-437, 2013 | 214 | 2013 |
Dimethyl fumarate blocks pro-inflammatory cytokine production via inhibition of TLR induced M1 and K63 ubiquitin chain formation VA McGuire, T Ruiz-Zorrilla Diez, CH Emmerich, S Strickson, MS Ritorto, ... Scientific reports 6 (1), 31159, 2016 | 115 | 2016 |
Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling S Strickson, CH Emmerich, ETH Goh, J Zhang, IR Kelsall, T Macartney, ... Proceedings of the National Academy of Sciences 114 (17), E3481-E3489, 2017 | 112 | 2017 |
The role of hybrid ubiquitin chains in the MyD88 and other innate immune signalling pathways P Cohen, S Strickson Cell Death & Differentiation 24 (7), 1153-1159, 2017 | 111 | 2017 |
The mechanism of activation of IRAK1 and IRAK4 by interleukin-1 and Toll-like receptor agonists S Vollmer, S Strickson, T Zhang, N Gray, KL Lee, VR Rao, P Cohen Biochemical Journal 474 (12), 2027-2038, 2017 | 94 | 2017 |
Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon β S Bakshi, J Taylor, S Strickson, T McCartney, P Cohen Biochemical Journal 474 (7), 1163-1174, 2017 | 74 | 2017 |
Oxidised IL-33 drives COPD epithelial pathogenesis via ST2-independent RAGE/EGFR signalling complex S Strickson, KF Houslay, VA Negri, Y Ohne, T Ottosson, RB Dodd, ... European Respiratory Journal 62 (3), 2023 | 12 | 2023 |
Oxidised IL-33 signals via RAGE/EGFR to drive a COPD-associated phenotype S Strickson, KF Houslay, VA Negri, Y Ohne, T Ottosson, RB Dodd, ... European Respiratory Journal 60 (suppl 66), 2022 | 7 | 2022 |
Why are the phenotypes of TRAF6 knock-in and TRAF6 knock-out mice so different? T Petrova, K Bennett, S Nanda, S Strickson, CL Scudamore, AR Prescott, ... Plos one 17 (2), e0263151, 2022 | 4 | 2022 |
Proteomic analysis in primary T cells reveals IL-7 alters T cell receptor thresholding via CYTIP/cytohesin/LFA-1 localisation and activation RML Queiroz, SC Piper, JS Rees, S Strickson, E Briend, CP Low, ... Biochemical Journal 479 (3), 225-243, 2022 | 1 | 2022 |
Distinct Pharmacological Profiles of IL-33 Antibodies S Cohen, S Strickson, IC Scott, A Collinson, G Rees, CC Huntington, ... B32. BIOMARKERS AND TRANSLATIONAL STUDIES IN COPD AND CHRONIC AIRWAYS …, 2024 | | 2024 |
Modelling bronchial epithelial-fibroblast cross-talk in idiopathic pulmonary fibrosis (IPF) using a human-derived in vitro air liquid interface (ALI) culture SL Barron, O Wyatt, A O’Connor, D Mansfield, E Suzanne Cohen, ... Scientific Reports 14 (1), 240, 2024 | | 2024 |
Tozorakimab (Anti-IL-33) Rebalances COPD Epithelium Enhancing Club Cell Activities and Reshaping Viral Responses X Romero Ros, S Strickson, V Negri, A O'Connor, O Wyatt, T baker, ... C69. PRECLINICAL COPD MODELS: IN VITRO, EX VIVO, IN VIVO, A5708-A5708, 2023 | | 2023 |
Methods of using il-33 antagonists R Dagher, K Houslay, M Ghaedi, S Strickson, ES Cohen, M Belvisi, ... US Patent App. 17/755,605, 2022 | | 2022 |
Anti il-33 therapeutic agent for treating renal disorders DJ Baker, CPM QUINN, KJ Woollard, S Asha, EL MARIN, B Musial, ... US Patent App. 17/755,604, 2022 | | 2022 |
Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon S Bakshi, J Taylor, S Strickson, T Macartney, P Cohen | | 2017 |
How the ubiquitin system triggers the activation of the MyD88 signalling network S Strickson University of Dundee, 2015 | | 2015 |
Biochemical Journal www. biochemj. org S STRICKSON, DG CAMPBELL, CH EMMERICH, A KNEBEL, L PLATER, ... Biochem. J 451, 427-437, 2013 | | 2013 |