Multiplexed genome regulation in vivo with hyper-efficient Cas12a LY Guo, J Bian, AE Davis, P Liu, HR Kempton, X Zhang, A Chemparathy, ... Nature cell biology 24 (4), 590-600, 2022 | 45 | 2022 |
NMNAT2 is downregulated in glaucomatous RGCs, and RGC-specific gene therapy rescues neurodegeneration and visual function F Fang, P Zhuang, X Feng, P Liu, D Liu, H Huang, L Li, W Chen, L Liu, ... Molecular Therapy 30 (4), 1421-1431, 2022 | 36 | 2022 |
Single-cell transcriptome analysis of regenerating RGCs reveals potent glaucoma neural repair genes L Li, F Fang, X Feng, P Zhuang, H Huang, P Liu, L Liu, AZ Xu, LS Qi, ... Neuron 110 (16), 2646-2663. e6, 2022 | 32 | 2022 |
Identification and Functional Analysis of a SLC 33 A 1: c. 339 T> G (p. S er113 A rg) Variant in the Original SPG 42 Family F Mao, Z Li, B Zhao, P Lin, P Liu, M Zhai, Q Liu, C Shao, W Sun, Y Gong Human mutation 36 (2), 240-249, 2015 | 21 | 2015 |
Chronic mild and acute severe glaucomatous neurodegeneration derived from silicone oil-induced ocular hypertension F Fang, J Zhang, P Zhuang, P Liu, L Li, H Huang, HC Webber, Y Xu, L Liu, ... Scientific reports 11 (1), 9052, 2021 | 20 | 2021 |
S113R mutation in SLC33A1 leads to neurodegeneration and augmented BMP signaling in a mouse model P Liu, B Jiang, J Ma, P Lin, Y Zhang, C Shao, W Sun, Y Gong Disease Models & Mechanisms 10 (1), 53-62, 2017 | 16 | 2017 |
Differential effects of SARM1 inhibition in traumatic glaucoma and EAE optic neuropathies P Liu, W Chen, H Jiang, H Huang, L Liu, F Fang, L Li, X Feng, D Liu, ... Molecular Therapy-Nucleic Acids 32, 13-27, 2023 | 11 | 2023 |
Longitudinal in vivo Ca2+ imaging reveals dynamic activity changes of diseased retinal ganglion cells at the single-cell level L Li, X Feng, F Fang, DA Miller, S Zhang, P Zhuang, H Huang, P Liu, J Liu, ... Proceedings of the National Academy of Sciences 119 (48), e2206829119, 2022 | 9 | 2022 |
Maprotiline restores ER homeostasis and rescues neurodegeneration via Histamine Receptor H1 inhibition in retinal ganglion cells W Chen, P Liu, D Liu, H Huang, X Feng, F Fang, L Li, J Wu, L Liu, ... Nature Communications 13 (1), 6796, 2022 | 8 | 2022 |
RGC-specific ATF4 and/or CHOP deletion rescues glaucomatous neurodegeneration and visual function F Fang, P Liu, H Huang, X Feng, L Li, Y Sun, RJ Kaufman, Y Hu Molecular Therapy-Nucleic Acids 33, 286-295, 2023 | 7 | 2023 |
Neuronal NMNAT2 overexpression does not achieve significant neuroprotection in experimental autoimmune encephalomyelitis/optic neuritis P Liu, H Huang, F Fang, L Liu, L Li, X Feng, W Chen, R Dalal, Y Sun, Y Hu Frontiers in cellular neuroscience 15, 754651, 2021 | 6 | 2021 |
Proteomic analysis of the cullin 4B interactome using proximity‐dependent biotinylation in living cells H Zhang, S Li, P Liu, FHF Lee, AHC Wong, F Liu Proteomics 17 (8), 1600163, 2017 | 5 | 2017 |
The UPR maintains proteostasis and the viability and function of hippocampal neurons in adult mice P Liu, MR Karim, A Covelo, Y Yue, MK Lee, W Lin International journal of molecular sciences 24 (14), 11542, 2023 | 3 | 2023 |
Multiplex CRISPR genome regulation in mouse retina with hyper-efficient Cas12a LY Guo, J Bian, AE Davis, P Liu, HR Kempton, X Zhang, A Chemparathy, ... | 1 | 2022 |
A novel function of optineurin in axonal mitochondria transport for axon integrity and regeneration Y Hu, D Liu, H Webber, F Bian, M Prakash, L Li, IJ You, X Feng, H Yang, ... Investigative Ophthalmology & Visual Science 65 (7), 944-944, 2024 | | 2024 |
Optineurin-facilitated axonal mitochondria delivery promotes neuroprotection and axon regeneration D Liu, HC Webber, F Bian, Y Xu, M Prakash, X Feng, M Yang, H Yang, ... bioRxiv, 2024 | | 2024 |
Neuroprotection of RGC-specific ATF4 Deletion in Mouse Glaucoma Model L Li, F Fang, P Liu, H Huang, X Feng, Y Hu Investigative Ophthalmology & Visual Science 64 (8), 1903-1903, 2023 | | 2023 |
In Vivo Evaluation of Naïve and Diseased RGC Activities at Single-Cell Level L Li, F Fang, X Feng, S Zhang, DA Miller, P Zhuang, H Huang, P Liu, J Liu, ... Investigative Ophthalmology & Visual Science 63 (7), 1849-1849, 2022 | | 2022 |
NMNAT2 and NAD+ are Downregulated in Glaucomatous RGCs and Overexpression of NMNAT2 Rescues Glaucomatous Neurodegeneration D Liu, F Fang, P Zhuang, X Feng, P Liu, H Huang, L Li, W Chen, L Liu, ... Investigative Ophthalmology & Visual Science 63 (7), 1135-1135, 2022 | | 2022 |
Neuroprotection of SARM1 Inhibition in Traumatic and Glaucomatous but not in EAE Optic Neuropathies P Liu, H Huang, W Chen, F Fang, L Li, X Feng, L Liu, D Liu, R Dalal, ... Investigative Ophthalmology & Visual Science 63 (7), 1136-1136, 2022 | | 2022 |