Exercise training remodels human skeletal muscle mitochondrial fission and fusion machinery towards a pro‐elongation phenotype CL Axelrod, CE Fealy, A Mulya, JP Kirwan Acta Physiologica 225 (4), e13216, 2019 | 188 | 2019 |
Mitochondrial dynamics in skeletal muscle insulin resistance and type 2 diabetes CÁE Fealy, A Mulya, CL Axelrod, JP Kirwan Translational Research 202, 69-82, 2018 | 60 | 2018 |
BAM15‐mediated mitochondrial uncoupling protects against obesity and improves glycemic control CL Axelrod, WT King, G Davuluri, RC Noland, J Hall, M Hull, WS Dantas, ... EMBO Molecular Medicine 12 (7), e12088, 2020 | 57 | 2020 |
Lipids activate skeletal muscle mitochondrial fission and quality control networks to induce insulin resistance in humans CL Axelrod, CE Fealy, ML Erickson, G Davuluri, H Fujioka, WS Dantas, ... Metabolism 121, 154803, 2021 | 46 | 2021 |
Exercise-induced increases in insulin sensitivity after bariatric surgery are mediated by muscle extracellular matrix remodeling WS Dantas, H Roschel, IH Murai, S Gil, G Davuluri, CL Axelrod, S Ghosh, ... Diabetes 69 (8), 1675-1691, 2020 | 41 | 2020 |
Blocking ActRIIB and restoring appetite reverses cachexia and improves survival in mice with lung cancer AL Queiroz, E Dantas, S Ramsamooj, A Murthy, M Ahmed, ERM Zunica, ... Nature Communications 13 (1), 4633, 2022 | 37 | 2022 |
β-Hydroxybutyrate is reduced in humans with obesity-related NAFLD and displays a dose-dependent effect on skeletal muscle mitochondrial respiration in vitro JT Mey, ML Erickson, CL Axelrod, WT King, CA Flask, AJ McCullough, ... American Journal of Physiology-Endocrinology and Metabolism 319 (1), E187-E195, 2020 | 37 | 2020 |
Lipids and ketones dominate metabolism at the expense of glucose control in pulmonary arterial hypertension: a hyperglycaemic clamp and metabolomics study JT Mey, A Hari, CL Axelrod, CE Fealy, ML Erickson, JP Kirwan, RA Dweik, ... European Respiratory Journal 55 (4), 2020 | 37 | 2020 |
Mitochondrial uncoupling attenuates sarcopenic obesity by enhancing skeletal muscle mitophagy and quality control WS Dantas, ERM Zunica, EC Heintz, B Vandanmagsar, ZE Floyd, Y Yu, ... Journal of cachexia, sarcopenia and muscle 13 (3), 1821-1836, 2022 | 29 | 2022 |
Sarcopenic obesity: emerging mechanisms and therapeutic potential CL Axelrod, WS Dantas, JP Kirwan Metabolism, 155639, 2023 | 23 | 2023 |
Exercise as a moderator of persistent neuroendocrine symptoms of COVID-19 CJ Rebello, CL Axelrod, CF Reynolds III, FL Greenway, JP Kirwan Exercise and sport sciences reviews 50 (2), 65-72, 2022 | 23 | 2022 |
UCC118 supplementation reduces exercise‐induced gastrointestinal permeability and remodels the gut microbiome in healthy humans CL Axelrod, CJ Brennan, G Cresci, D Paul, M Hull, CE Fealy, JP Kirwan Physiological Reports 7 (22), e14276, 2019 | 23 | 2019 |
CRISPR/Cas9-engineered Drosophila knock-in models to study VCP diseases JM Wall, A Basu, ERM Zunica, OS Dubuisson, K Pergola, JP Broussard, ... Disease models & mechanisms 14 (7), dmm048603, 2021 | 20 | 2021 |
Insulin resistance persists despite a metabolically healthy obesity phenotype KK Hoddy, CL Axelrod, JT Mey, A Hari, RA Beyl, JB Blair, WS Dantas, ... Obesity 30 (1), 39-44, 2022 | 17 | 2022 |
Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano [3, 4-b] pyrazine BAM15 ERM Zunica, CL Axelrod, E Cho, G Spielmann, G Davuluri, ... Cancer & Metabolism 9, 1-20, 2021 | 17 | 2021 |
Gastric bypass surgery improves the skeletal muscle ceramide/S1P ratio and upregulates the AMPK/SIRT1/PGC-1α pathway in Zucker diabetic fatty rats H Huang, A Aminian, M Hassan, O Dan, CL Axelrod, PR Schauer, ... Obesity surgery 29, 2158-2165, 2019 | 16 | 2019 |
Roux-en-Y gastric bypass restores islet function and morphology independent of body weight in ZDF rats JD Mosinski, A Aminian, CL Axelrod, E Batayyah, H Romero-Talamas, ... American Journal of Physiology-Endocrinology and Metabolism 320 (2), E392-E398, 2021 | 15 | 2021 |
Obesity management in the primary prevention of hepatocellular carcinoma ERM Zunica, EC Heintz, CL Axelrod, JP Kirwan Cancers 14 (16), 4051, 2022 | 14 | 2022 |
Rationale and study design for lifestyle intervention in preparation for pregnancy (LIPP): a randomized controlled trial ML Erickson, JT Mey, CL Axelrod, D Paul, L Gordesky, K Russell, ... Contemporary clinical trials 94, 106024, 2020 | 13 | 2020 |
GDF15 mediates the effect of skeletal muscle contraction on glucose-stimulated insulin secretion H Zhang, A Mulya, S Nieuwoudt, B Vandanmagsar, R McDowell, ... Diabetes 72 (8), 1070-1082, 2023 | 12 | 2023 |