Leveraging the Knorr pyrazole synthesis for the facile generation of thioester surrogates for use in native chemical ligation DT Flood, JCJ Hintzen, MJ Bird, PA Cistrone, JS Chen, PE Dawson Angewandte Chemie 130 (36), 11808-11813, 2018 | 162 | 2018 |
A peptide functionalized nanomotor as an efficient cell penetrating tool F Peng, Y Tu, A Adhikari, JCJ Hintzen, DWPM Löwik, DA Wilson Chemical Communications 53 (6), 1088-1091, 2017 | 56 | 2017 |
Targeting SARS-CoV-2 spike protein by stapled hACE2 peptides MN Maas, JCJ Hintzen, PMG Löffler, J Mecinović Chemical Communications 57 (26), 3283-3286, 2021 | 47 | 2021 |
Native chemical ligation of peptides and proteins PA Cistrone, MJ Bird, DT Flood, AP Silvestri, JCJ Hintzen, DA Thompson, ... Current protocols in chemical biology 11 (1), e61, 2019 | 34 | 2019 |
Rigid peptide macrocycles from on‐resin Glaser stapling PA Cistrone, AP Silvestri, JCJ Hintzen, PE Dawson ChemBioChem 19 (10), 1031-1035, 2018 | 32 | 2018 |
Trimethyllysine: from carnitine biosynthesis to epigenetics MN Maas, JCJ Hintzen, MRB Porzberg, J Mecinović International journal of molecular sciences 21 (24), 9451, 2020 | 29 | 2020 |
Probing lysine posttranslational modifications by unnatural amino acids MN Maas, JCJ Hintzen, J Mecinović Chemical Communications 58 (52), 7216-7231, 2022 | 22 | 2022 |
Installation of trimethyllysine analogs on intact histones via cysteine alkylation BJGE Pieters, JCJ Hintzen, Y Grobben, AHK Al Temimi, JJAG Kamps, ... Bioconjugate Chemistry 30 (3), 952-958, 2019 | 20 | 2019 |
Exploring the histone acylome through incorporation of γ-thialysine on histone tails G Proietti, G Rainone, JCJ Hintzen, J Mecinović Bioconjugate Chemistry 31 (3), 844-851, 2020 | 17 | 2020 |
β‐Actin peptide‐based inhibitors of histidine methyltransferase SETD3 JCJ Hintzen, L Moesgaard, S Kwiatkowski, J Drozak, J Kongsted, ... ChemMedChem 16 (17), 2695-2702, 2021 | 16 | 2021 |
Comparison of molecular recognition of trimethyllysine and trimethylthialysine by epigenetic reader proteins JCJ Hintzen, J Poater, K Kumar, AHK Al Temimi, BJGE Pieters, RS Paton, ... Molecules 25 (8), 1918, 2020 | 12 | 2020 |
Substrate-derived Sortase A inhibitors: targeting an essential virulence factor of Gram-positive pathogenic bacteria H Abujubara, JCJ Hintzen, S Rahimi, I Mijakovic, D Tietze, AA Tietze Chemical Science 14 (25), 6975-6985, 2023 | 9 | 2023 |
Amide-derived lysine analogues as substrates and inhibitors of histone lysine methyltransferases and acetyltransferases JCJ Hintzen, J Merx, MN Maas, SGHA Langens, PB White, TJ Boltje, ... Organic & Biomolecular Chemistry 20 (1), 173-181, 2022 | 6 | 2022 |
γ-Difluorolysine as a 19 F NMR probe for histone lysine methyltransferases and acetyltransferases JCJ Hintzen, Y Luo, MRB Porzberg, PB White, J Jian, G Proietti, ... Chemical Communications 57 (55), 6788-6791, 2021 | 6 | 2021 |
Histidine methyltransferase SETD3 methylates structurally diverse histidine mimics in actin JCJ Hintzen, H Ma, H Deng, A Witecka, SB Andersen, J Drozak, H Guo, ... Protein Science 31 (5), e4305, 2022 | 5 | 2022 |
Selenomethionine as an expressible handle for bioconjugations DT Flood, JCJ Hintzen, KW Knouse, DE Hill, C Lu, PA Cistrone, JS Chen, ... Proceedings of the National Academy of Sciences 118 (8), e2005164118, 2021 | 5 | 2021 |
Investigation of in vitro histone H3 glycosylation using H3 tail peptides J Merx, JCJ Hintzen, G Proietti, H Elferink, Y Wang, MRB Porzberg, ... Scientific Reports 12 (1), 19251, 2022 | 4 | 2022 |
Importance of Ile71 in β-actin on histidine methyltransferase SETD3 catalysis N Bilgin, L Moesgaard, MN Maas, JCJ Hintzen, A Witecka, J Drozak, ... Organic & Biomolecular Chemistry 20 (8), 1723-1730, 2022 | 3 | 2022 |
Substrate selectivity and inhibition of histidine JmjC hydroxylases MINA53 and NO66 VA Türkmen, JCJ Hintzen, A Tumber, L Moesgaard, E Salah, J Kongsted, ... RSC Chemical Biology 4 (3), 235-243, 2023 | 2 | 2023 |
Reading and erasing of histone crotonyllysine mimics by the AF9 YEATS domain and SIRT2 deacylase N Bilgin, VA Türkmen, N Hammami, NR Christensen, JCJ Hintzen, ... Bioorganic & Medicinal Chemistry 95, 117500, 2023 | 1 | 2023 |