The furan fatty acid metabolite CMPF is elevated in diabetes and induces β cell dysfunction KJ Prentice, L Luu, EM Allister, Y Liu, LS Jun, KW Sloop, AB Hardy, L Wei, ... Cell metabolism 19 (4), 653-666, 2014 | 177 | 2014 |
The functional and molecular characterisation of human embryonic stem cell-derived insulin-positive cells compared with adult pancreatic beta cells CL Basford, KJ Prentice, AB Hardy, F Sarangi, SJ Micallef, X Li, Q Guo, ... Diabetologia 55, 358-371, 2012 | 160 | 2012 |
β-cell uncoupling protein 2 regulates reactive oxygen species production, which influences both insulin and glucagon secretion CA Robson-Doucette, S Sultan, EM Allister, JD Wikstrom, V Koshkin, ... Diabetes 60 (11), 2710-2719, 2011 | 156 | 2011 |
Adipokine FABP4 integrates energy stores and counterregulatory metabolic responses KJ Prentice, J Saksi, GS Hotamisligil Journal of Lipid Research 60 (4), 734-740, 2019 | 143 | 2019 |
A predictive metabolic signature for the transition from gestational diabetes mellitus to type 2 diabetes A Allalou, A Nalla, KJ Prentice, Y Liu, M Zhang, FF Dai, X Ning, ... Diabetes 65 (9), 2529-2539, 2016 | 140 | 2016 |
Elevated medium-chain acylcarnitines are associated with gestational diabetes mellitus and early progression to type 2 diabetes and induce pancreatic β-cell dysfunction B Batchuluun, D Al Rijjal, KJ Prentice, JA Eversley, E Burdett, H Mohan, ... Diabetes 67 (5), 885-897, 2018 | 106 | 2018 |
The loss of Sirt1 in mouse pancreatic beta cells impairs insulin secretion by disrupting glucose sensing L Luu, FF Dai, KJ Prentice, X Huang, AB Hardy, JB Hansen, Y Liu, ... Diabetologia 56, 2010-2020, 2013 | 90 | 2013 |
Characterization of zinc influx transporters (ZIPs) in pancreatic β cells: roles in regulating cytosolic zinc homeostasis and insulin secretion Y Liu, B Batchuluun, L Ho, D Zhu, KJ Prentice, A Bhattacharjee, M Zhang, ... Journal of Biological Chemistry 290 (30), 18757-18769, 2015 | 86 | 2015 |
UCP2 regulates the glucagon response to fasting and starvation EM Allister, CA Robson-Doucette, KJ Prentice, AB Hardy, S Sultan, ... Diabetes 62 (5), 1623-1633, 2013 | 86 | 2013 |
Effects of high-fat diet feeding on Znt8-null mice: differences between β-cell and global knockout of Znt8 AB Hardy, N Wijesekara, I Genkin, KJ Prentice, A Bhattacharjee, D Kong, ... American Journal of Physiology-Endocrinology and Metabolism 302 (9), E1084-E1096, 2012 | 79 | 2012 |
Rapid elevation in CMPF may act as a tipping point in diabetes development Y Liu, KJ Prentice, JA Eversley, C Hu, B Batchuluun, K Leavey, ... Cell reports 14 (12), 2889-2900, 2016 | 60 | 2016 |
A hormone complex of FABP4 and nucleoside kinases regulates islet function KJ Prentice, J Saksi, LT Robertson, GY Lee, KE Inouye, K Eguchi, A Lee, ... Nature 600 (7890), 720-726, 2021 | 50 | 2021 |
New roles of syntaxin-1A in insulin granule exocytosis and replenishment T Liang, T Qin, L Xie, S Dolai, D Zhu, KJ Prentice, M Wheeler, Y Kang, ... Journal of biological chemistry 292 (6), 2203-2216, 2017 | 45 | 2017 |
CMPF, a metabolite formed upon prescription omega-3-acid ethyl ester supplementation, prevents and reverses steatosis KJ Prentice, SG Wendell, Y Liu, JA Eversley, SR Salvatore, H Mohan, ... EBioMedicine 27, 200-213, 2018 | 43 | 2018 |
Zip4 mediated zinc influx stimulates insulin secretion in pancreatic beta cells AB Hardy, KJ Prentice, S Froese, Y Liu, GK Andrews, MB Wheeler PloS one 10 (3), e0119136, 2015 | 42 | 2015 |
Glucolipotoxic conditions induce β-cell iron import, cytosolic ROS formation and apoptosis JB Hansen, LRB Dos Santos, Y Liu, KJ Prentice, F Teudt, M Tonnesen, ... Journal of Molecular Endocrinology 61 (2), 69-77, 2018 | 34 | 2018 |
Synthesis and characterization of urofuranoic acids: in vivo metabolism of 2-(2-Carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic acid (CMPF) and effects on in vitro insulin … E Nagy, Y Liu, KJ Prentice, KW Sloop, PE Sanders, B Batchuluun, ... Journal of Medicinal Chemistry 60 (5), 1860-1875, 2017 | 30 | 2017 |
Incretin hormones and the expanding families of glucagon‐like sequences and their receptors DM Irwin, KJ Prentice Diabetes, Obesity and Metabolism 13, 69-81, 2011 | 28 | 2011 |
Adipocyte function and the development of cardiometabolic disease M Giroud, H Jodeleit, KJ Prentice, A Bartelt The Journal of Physiology 600 (5), 1189-1208, 2022 | 24 | 2022 |
3‐carboxy‐4‐methyl‐5‐propyl‐2‐furanpropanoic acid (CMPF) prevents high fat diet‐induced insulin resistance via maintenance of hepatic lipid homeostasis H Mohan, SL Brandt, JH Kim, F Wong, M Lai, KJ Prentice, D Al Rijjal, ... Diabetes, Obesity and Metabolism 21 (1), 61-72, 2019 | 20 | 2019 |