| Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation H Hashimoto, Y Liu, AK Upadhyay, Y Chang, SB Howerton, PM Vertino, ... Nucleic Acids Research 40 (11), 4841-4849, 2012 | 541 | 2012 |
| The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix H Hashimoto, JR Horton, X Zhang, M Bostick, SE Jacobsen, X Cheng Nature 455 (7214), 826-829, 2008 | 476 | 2008 |
| Molecular coupling of DNA methylation and histone methylation H Hashimoto, PM Vertino, X Cheng Epigenomics 2 (5), 657-669, 2010 | 318 | 2010 |
| Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA H Hashimoto, D Wang, JR Horton, X Zhang, VG Corces, X Cheng Molecular Cell 66 (5), 711-720.e3, 2017 | 241 | 2017 |
| Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylation H Hashimoto, S Hong, AS Bhagwat, X Zhang, X Cheng Nucleic Acids Research 40 (20), 10203-10214, 2012 | 178 | 2012 |
| UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications H Hashimoto, JR Horton, X Zhang, X Cheng Epigenetics 4 (1), 8-14, 2009 | 155 | 2009 |
| Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA H Hashimoto, JE Pais, X Zhang, L Saleh, ZQ Fu, N Dai, IR Corrêa, ... Nature 506 (7488), 391-395, 2014 | 145 | 2014 |
| Independent role for presynaptic FMRP revealed by an FMR1 missense mutation associated with intellectual disability and seizures LK Myrick, PY Deng, H Hashimoto, YM Oh, Y Cho, MJ Poidevin, JA Suhl, ... Proceedings of the National Academy of Sciences 112 (4), 949–956, 2015 | 128 | 2015 |
| Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence H Hashimoto, YO Olanrewaju, Y Zheng, GG Wilson, X Zhang, X Cheng Genes & Development 28 (20), 2304-2313, 2014 | 127 | 2014 |
| Selective Non-Nucleoside Inhibitors of Human DNA Methyltransferases Active in Cancer Including Cancer Stem Cells S Valente, Y Liu, M Schnekenburger, C Zwergel, S Cosconati, C Gros, ... Journal of medicinal chemistry 57 (3), 701-713, 2014 | 125 | 2014 |
| Excision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: structural basis and implications for active DNA demethylation H Hashimoto, X Zhang, X Cheng Nucleic Acids Research 40 (17), 8276-8284, 2012 | 115 | 2012 |
| Human FMRP contains an integral tandem Agenet (Tudor) and KH motif in the amino terminal domain LK Myrick, H Hashimoto, X Cheng, ST Warren Human Molecular Genetics 24 (6), 1733-1740, 2015 | 114 | 2015 |
| Structural basis for Klf4 recognition of methylated DNA Y Liu, YO Olanrewaju, Y Zheng, H Hashimoto, RM Blumenthal, X Zhang, ... Nucleic Acids Research 42 (8), 4859-4867, 2014 | 98 | 2014 |
| MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma D Wang, H Hashimoto, X Zhang, BG Barwick, S Lonial, LH Boise, ... Nucleic Acids Research 45 (5), 2396-2407, 2017 | 83 | 2017 |
| Histone H1 null vertebrate cells exhibit altered nucleosome architecture H Hashimoto, Y Takami, E Sonoda, T Iwasaki, H Iwano, M Tachibana, ... Nucleic acids research 38 (11), 3533-3545, 2010 | 76 | 2010 |
| Structural basis for human PHF2 Jumonji domain interaction with metal ions JR Horton, AK Upadhyay, H Hashimoto, X Zhang, X Cheng Journal of molecular biology 406 (1), 1-8, 2011 | 60 | 2011 |
| Histone H1 variant, H1R is involved in DNA damage response H Hashimoto, E Sonoda, Y Takami, H Kimura, T Nakayama, M Tachibana, ... DNA repair 6 (11), 1584-1595, 2007 | 58 | 2007 |
| The mechanisms of generation, recognition, and erasure of DNA 5-methylcytosine and thymine oxidations H Hashimoto, X Zhang, PM Vertino, X Cheng Journal of biological chemistry 290 (34), 20723-20733, 2015 | 45 | 2015 |
| Structural basis of specific DNA binding by the transcription factor ZBTB24 R Ren, S Hardikar, JR Horton, Y Lu, Y Zeng, AK Singh, K Lin, LD Coletta, ... Nucleic acids research 47 (16), 8388-8398, 2019 | 38 | 2019 |
| Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA H Hashimoto, JE Pais, N Dai, IR Corrêa, X Zhang, Y Zheng, X Cheng Nucleic acids research 43 (22), 10713-10721, 2015 | 38 | 2015 |
