Oncogenic role of fusion-circRNAs derived from cancer-associated chromosomal translocations J Guarnerio, M Bezzi, JC Jeong, SV Paffenholz, K Berry, MM Naldini, ... Cell 165 (2), 289-302, 2016 | 739 | 2016 |
The dark matter of the cancer genome: aberrations in regulatory elements, untranslated regions, splice sites, non‐coding RNA and synonymous mutations S Diederichs, L Bartsch, JC Berkmann, K Fröse, J Heitmann, C Hoppe, ... EMBO molecular medicine 8 (5), 442-457, 2016 | 280 | 2016 |
Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging R Bogeska, AM Mikecin, P Kaschutnig, M Fawaz, M Büchler-Schäff, D Le, ... Cell stem cell 29 (8), 1273-1284. e8, 2022 | 106 | 2022 |
Perception of the 2020 SARS-CoV-2 pandemic among medical professionals in Germany: results from a nationwide online survey P Paffenholz, A Peine, M Hellmich, SV Paffenholz, L Martin, M Luedde, ... Emerging microbes & infections 9 (1), 1590-1599, 2020 | 69 | 2020 |
Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants FJ Sánchez-Rivera, BJ Diaz, ER Kastenhuber, H Schmidt, A Katti, ... Nature biotechnology 40 (6), 862-873, 2022 | 58 | 2022 |
Senescence induction dictates response to chemo-and immunotherapy in preclinical models of ovarian cancer SV Paffenholz, C Salvagno, YJ Ho, M Limjoco, T Baslan, S Tian, A Kulick, ... Proceedings of the National Academy of Sciences 119 (5), e2117754119, 2022 | 51 | 2022 |
Game changers in science and technology-now and beyond UAK Betz, L Arora, RA Assal, H Azevedo, J Baldwin, MS Becker, ... Technological Forecasting and Social Change 193, 122588, 2023 | 47 | 2023 |
Safety and activity of selinexor in patients with myelodysplastic syndromes or oligoblastic acute myeloid leukaemia refractory to hypomethylating agents: a single-centre … J Taylor, X Mi, AV Penson, SV Paffenholz, K Alvarez, A Sigler, SS Chung, ... The Lancet Haematology 7 (8), e566-e574, 2020 | 17 | 2020 |
Hematopoietic stem cells fail to regenerate following inflammatory challenge R Bogeska, P Kaschutnig, M Fawaz, AM Mikecin, M Büchler-Schäff, ... Biorxiv, 2020.08. 01.230433, 2020 | 14 | 2020 |
Developing uPAR CAR T Cells for High-Grade Serous Ovarian Cancer Z Zhang, X Fang, Y Ho, S Haubner, F Kogel, C Hinterleitner, S Paffenholz, ... Cancer Research 84 (6_Supplement), 115-115, 2024 | | 2024 |
A Phase II Study of Selinexor, a First-in-Class XPO1 Inhibitor, in Patients with Myelodysplastic Syndromes and Oligoblastic Acute Myeloid Leukaemia Refractory to … J Taylor, X Mi, AV Penson, SV Paffenholz, K Alvarez, A Sigler, SS Chung, ... The Lancet. Haematology 7 (8), e566, 2020 | | 2020 |
No Evidence for Hematopoietic Stem Cell Self-Renewal in-Vivo Following Inflammatory Challenge R Bogeska, P Kaschutnig, SV Paffenholz, J Knoch, JP Mallm, M Fawaz, ... Blood 134, 456, 2019 | | 2019 |
Oncogenic Mutations in XPO1 Promote Lymphoid Transformation By Altering Nuclear/Cytoplasmic Localization of NFκB Signaling Intermediates J Taylor, XJ Zhang, SV Paffenholz, AV Penson, M Chang, C Marcelus, ... Blood, The Journal of the American Society of Hematology 130 (Suppl_1), 879-879, 2017 | | 2017 |
HSCs completely fail to regenerate following inflammatory challenge, leading to aged hematopoiesis R Bogeska, P Kaschutnig, S Paffenholz, J Knoch, D Walter, JP Mallm, ... Experimental Hematology 53, S124, 2017 | | 2017 |
Hematopoietic Stem Cells Fail to Regenerate In Vivo Following Inflammatory Stress R Bogeska, P Kaschutnig, S Paffenholz, J Maassen, JP Mallm, F Wertek, ... Blood, The Journal of the American Society of Hematology 128 (22), 1472-1472, 2016 | | 2016 |
Functional and molecular segregation of in vitro specified hematopoietic stem and progenitor cells using a HOXB4 knock-in reporter P Kaschutnig, I Bayindir-Buchhalter, M Thier, W Nadler, S Hanke, ... Experimental Hematology 44 (9), S84, 2016 | | 2016 |