Molecular architecture of the human caveolin-1 complex JC Porta, B Han, A Gulsevin, JM Chung, Y Peskova, S Connolly, ... Science advances 8 (19), eabn7232, 2022 | 63 | 2022 |
Benchmarking AlphaFold2 on peptide structure prediction EF McDonald, T Jones, L Plate, J Meiler, A Gulsevin Structure 31 (1), 111-119. e2, 2023 | 45 | 2023 |
Modeling immunity with Rosetta: methods for antibody and antigen design CT Schoeder, S Schmitz, J Adolf-Bryfogle, AM Sevy, JA Finn, MF Sauer, ... Biochemistry 60 (11), 825-846, 2021 | 32 | 2021 |
Allosteric agonism of α7 nicotinic acetylcholine receptors: Receptor modulation outside the orthosteric site A Gulsevin, RL Papke, C Stokes, S Garai, GA Thakur, M Quadri, ... Molecular pharmacology 95 (6), 606-614, 2019 | 26 | 2019 |
Macroscopic and microscopic activation of α7 nicotinic acetylcholine receptors by the structurally unrelated allosteric agonist-positive allosteric modulators (ago-PAMs) B-973B … M Quadri, S Garai, GA Thakur, C Stokes, A Gulsevin, NA Horenstein, ... Molecular pharmacology 95 (1), 43-61, 2019 | 22 | 2019 |
Sulfonium as a surrogate for ammonium: a new α7 nicotinic acetylcholine receptor partial agonist with desensitizing activity M Quadri, C Stokes, A Gulsevin, ACJ Felts, KA Abboud, RL Papke, ... Journal of medicinal chemistry 60 (18), 7928-7934, 2017 | 17 | 2017 |
Silent agonists for α7 nicotinic acetylcholine receptors RL Papke, M Quadri, A Gulsevin Pharmacological Research 190, 106736, 2023 | 10 | 2023 |
In silico modeling of the α7 nicotinic acetylcholine receptor: new pharmacological challenges associated with multiple modes of signaling A Gulsevin, RL Papke, N Horenstein Mini reviews in medicinal chemistry 20 (10), 841-864, 2020 | 10 | 2020 |
Nicotinic receptor pharmacology in silico: Insights and challenges A Gulsevin Neuropharmacology 177, 108257, 2020 | 9 | 2020 |
An investigation of three-finger toxin—nAChR Interactions through Rosetta protein docking A Gulsevin, J Meiler Toxins 12 (9), 598, 2020 | 8 | 2020 |
Template-free prediction of a new monotopic membrane protein fold and assembly by AlphaFold2 A Gulsevin, B Han, JC Porta, HS Mchaourab, J Meiler, AK Kenworthy Biophysical Journal 122 (11), 2041-2052, 2023 | 7 | 2023 |
Prediction of amphipathic helix-membrane interactions with Rosetta A Gulsevin, J Meiler Biophysical Journal 120 (3), 19a, 2021 | 7 | 2021 |
The allosteric activation of α7 nAChR by α-conotoxin MrIC is modified by mutations at the vestibular site A Gulsevin, RL Papke, C Stokes, HNT Tran, AH Jin, I Vetter, J Meiler Toxins 13 (8), 555, 2021 | 6 | 2021 |
Structural analysis of the P132L disease mutation in caveolin-1 reveals its role in the assembly of oligomeric complexes B Han, A Gulsevin, S Connolly, T Wang, B Meyer, J Porta, A Tiwari, ... Journal of Biological Chemistry 299 (4), 2023 | 5 | 2023 |
Benchmarking peptide structure prediction with AlphaFold2 A Gulsevin, J Meiler bioRxiv, 2022.02. 17.480937, 2022 | 4 | 2022 |
Template-free prediction of a new monotopic membrane protein fold and oligomeric assembly by Alphafold2 A Gulsevin, B Han, J Porta, H Mchaourab, J Meiler, AK Kenworthy Biophysical Journal 122 (3), 194a, 2023 | 3 | 2023 |
Design principles of caveolins across metazoa and beyond B Han, LFL Wilson, A Gulsevin, J Meiler, E Karakas, AK Kenworthy bioRxiv, 2022.11. 15.516482, 2022 | 3 | 2022 |
Veratridine Can Bind to a Site at the Mouth of the Channel Pore at Human Cardiac Sodium Channel NaV1.5 A Gulsevin, AM Glazer, T Shields, BM Kroncke, DM Roden, J Meiler International Journal of Molecular Sciences 23 (4), 2225, 2022 | 3 | 2022 |
The novel non-hallucinogenic compound DM506 (3-methyl-1, 2, 3, 4, 5, 6-hexahydroazepino [4, 5-b] indole) induces sedative-and anxiolytic-like activity in mice by a mechanism … HR Arias, D Rudin, DJ Hines, A Contreras, A Gulsevin, D Manetti, ... European Journal of Pharmacology 966, 176329, 2024 | 2 | 2024 |
Structural characterization of a breast cancer-associated mutation in caveolin-1 B Han, A Gulsevin, S Connolly, T Wang, J Porta, A Tiwari, A Deng, ... bioRxiv, 2022.05. 23.493104, 2022 | 2 | 2022 |