MicroRNAs in development and disease D Sayed, M Abdellatif Physiological reviews 91 (3), 827-887, 2011 | 1334 | 2011 |
MicroRNAs play an essential role in the development of cardiac hypertrophy D Sayed, C Hong, IY Chen, J Lypowy, M Abdellatif Circulation research 100 (3), 416-424, 2007 | 1079 | 2007 |
Downregulation of miR-199a derepresses hypoxia-inducible factor-1α and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes S Rane, M He, D Sayed, H Vashistha, A Malhotra, J Sadoshima, ... Circulation research 104 (7), 879-886, 2009 | 722 | 2009 |
MicroRNA-21 targets Sprouty2 and promotes cellular outgrowths D Sayed, S Rane, J Lypowy, M He, IY Chen, H Vashistha, L Yan, ... Molecular biology of the cell 19 (8), 3272-3282, 2008 | 500 | 2008 |
MicroRNA-21 is a downstream effector of AKT that mediates its antiapoptotic effects via suppression of Fas ligand D Sayed, M He, C Hong, S Gao, S Rane, Z Yang, M Abdellatif Journal of Biological Chemistry 285 (26), 20281-20290, 2010 | 419 | 2010 |
miR-206 mediates YAP-induced cardiac hypertrophy and survival Y Yang, DP Del Re, N Nakano, S Sciarretta, P Zhai, J Park, D Sayed, ... Circulation research 117 (10), 891-904, 2015 | 154 | 2015 |
GATA4 expression is primarily regulated via a miR-26b-dependent post-transcriptional mechanism during cardiac hypertrophy M Han, Z Yang, D Sayed, M He, S Gao, L Lin, S Yoon, M Abdellatif Cardiovascular research 93 (4), 645-654, 2012 | 113 | 2012 |
Histone H2A. z is essential for cardiac myocyte hypertrophy but opposed by silent information regulator 2α IY Chen, J Lypowy, J Pain, D Sayed, S Grinberg, RR Alcendor, ... Journal of Biological Chemistry 281 (28), 19369-19377, 2006 | 109 | 2006 |
An antagonism between the AKT and beta-adrenergic signaling pathways mediated through their reciprocal effects on miR-199a-5p S Rane, M He, D Sayed, L Yan, D Vatner, M Abdellatif Cellular signalling 22 (7), 1054-1062, 2010 | 101 | 2010 |
AKT-ing via microRNA D Sayed, M Abdellatif Cell Cycle 9 (16), 3233-3237, 2010 | 64 | 2010 |
Transcriptional regulation patterns revealed by high resolution chromatin immunoprecipitation during cardiac hypertrophy D Sayed, M He, Z Yang, L Lin, M Abdellatif Journal of Biological Chemistry 288 (4), 2546-2558, 2013 | 63 | 2013 |
MicroRNA with a MacroFunction S Rane, D Sayed, M Abdellatif Cell Cycle 6 (15), 1850-1855, 2007 | 54 | 2007 |
GTPase activating protein (Sh3 domain) binding protein 1 regulates the processing of microRNA-1 during cardiac hypertrophy M He, Z Yang, M Abdellatif, D Sayed PLoS One 10 (12), e0145112, 2015 | 39 | 2015 |
Glucocorticoid receptor‐binding and transcriptome signature in cardiomyocytes E Severinova, S Alikunju, W Deng, P Dhawan, N Sayed, D Sayed Journal of the American Heart Association 8 (6), e011484, 2019 | 33 | 2019 |
Acute targeting of general transcription factor IIB restricts cardiac hypertrophy via selective inhibition of gene transcription D Sayed, Z Yang, M He, JM Pfleger, M Abdellatif Circulation: Heart Failure 8 (1), 138-148, 2015 | 26 | 2015 |
Oxoglutarate dehydrogenase and acetyl-CoA acyltransferase 2 selectively associate with H2A. Z-occupied promoters and are required for histone modifications S Choi, J Pfleger, YH Jeon, Z Yang, M He, H Shin, D Sayed, S Astrof, ... Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1862 (10), 194436, 2019 | 18 | 2019 |
Recruitment of RNA polymerase II to metabolic gene promoters is inhibited in the failing heart possibly through PGC-1α (peroxisome proliferator-activated receptor-γ coactivator … S Bhat, A Chin, A Shirakabe, Y Ikeda, S Ikeda, P Zhai, C Hsu, D Sayed, ... Circulation: Heart Failure 12 (3), e005529, 2019 | 16 | 2019 |
Transcriptional regulation mediated by H2A. Z via ANP32e-dependent inhibition of protein phosphatase 2A H Shin, M He, Z Yang, YH Jeon, J Pfleger, D Sayed, M Abdellatif Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1861 (5), 481-496, 2018 | 13 | 2018 |
HIF1α regulates early metabolic changes due to activation of innate immunity in nuclear reprogramming C Liu, H Ruan, F Himmati, MT Zhao, CC Chen, M Makar, IY Chen, ... Stem cell reports 14 (2), 192-200, 2020 | 11 | 2020 |
MicroRNAs challenge the status quo of therapeutic targeting D Sayed, S Rane, M Abdellatif Journal of cardiovascular translational research 2, 100-107, 2009 | 10 | 2009 |